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Special Issue "Advances in Proteomic Research for the Characterization of Bioactive Molecules"
Deadline for manuscript submissions: closed (30 November 2017).
Institut des Biomolécules Max Mousseron, UMR 5247, Université Montpellier - CNRS, Place Eugène Bataillon, 34095 Montpellier Cedex 5, France
Interests: venoms; peptides; proteomics; transcriptomics; drug discovery; integrated bioinformatics
Special Issues and Collections in MDPI journals
Bioactive molecules produced by some plants, microbes, and animals constitute a large reservoir of natural products with potential as new therapeutics, agrochemicals and cosmetics. Whereas small molecules (<500 Da) represent the majority of characterized biologically-active components, larger molecules, such as neuropeptides, hormones, toxins, and enzymes, are also of interest. However, until recently, the amount of starting material required for characterization limited the number of species that could be investigated. With the advent of more sensitive mass spectrometry instruments, coupled to transcriptomics and bioinformatics tools, researchers can, nowadays, interrogate virtually any species, from the smallest to the rarest. In addition, a deeper understanding of the biology/ecology of these species, as well as their evolution, can be inferred from such integrated approach, while providing a framework for the rational discovery of novel biomolecules. This Special Issue will contain articles describing new advances in proteomic research for the characterization of such bioactive molecules.
Topics of this Special Issue include, but are not limited to:
- Peptides and peptidomimetic drugs
- Imaging and analytical techniques
- Peptide-based proteomics databases
- New Bioinformatics approaches for the integration of proteomic and transcriptomic datasets
- Sample preparation for two-dimensional electrophoresis
- Sample preparation for protein mass spectrometry
- Enrichment for sub-proteomes
- Organelle proteomics
- Clinical applications of proteomics, such as biomarker discovery
- Proteomics of non-model organisms
Prof. Dutertre Sebastien
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.