Advances in Molecular Research on Antibacterial Nanoparticles
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Nanoscience".
Deadline for manuscript submissions: closed (30 March 2024) | Viewed by 228
Special Issue Editor
Special Issue Information
Dear Colleagues,
The development of multi-drug resistance (MDR) in different bacterial strains (Enterococci, Staphylococci, Klebsiella, Acinetobacter, Pseudomonas, and Enterobacter species) has become a serious threat over the globe. Numerous antibacterial agents have been developed; however, with the rise of MDR in bacteriological species, the therapeutic efficacy of currently available antibiotics and antibacterial agents is at risk. According to the World Health Organization (WHO), bacterial infections now cause 0.7 million lives each year. If we do not discover effective treatments to manage or eliminate these MDR bacteria, this figure might climb to ten million by 2050. Therefore, this has become obligatory to find alternate routes to tackle these MDR pathogenic microbes.
Nanotechnology, a promising and revolutionary field, has garnered much interest for its potential to address these issues. Nanotechnology is an interdisciplinary field of study that leverages fundamental concepts from many areas, such as biology, physics, engineering, and chemistry, to create unique approaches for manipulating minute particles, culminating in the fabrication of nanoparticles (NAPs). NAPs (metal, metal oxides, polymer-based, etc.) synthesized by various methods (chemical, physical, green, etc.) are widely used as antibacterial agents in catheter coatings, medical equipment disinfection, filters, dental hygiene, eye care, and topical ointments.
Antibacterial NAPs function by circumventing bacterial MDR mechanisms and reducing biofilm formation or other vital processes associated with their pathogenicity potential. Antibacterial NAPs are capable of penetrating the bacterial cell wall and membrane and interrupting vital molecular pathways. In conjunction with suitable antibiotics, they may exhibit synergy and aid in preventing the escalating MDR threat on a worldwide scale.
We invite researchers to contribute reviews, original research articles, and communications on molecular research on antibacterial nanoparticles, which will highlight the most innovative and exciting advancements in this area.
Dr. Shakeel Ahmad Khan
Guest Editor
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Keywords
- nanoparticles
- antibacterial
- biofilm inhibition
- multi-drug resistance
- nanomedicine
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