Peripheral Neuropathies: Molecular Research and Novel Therapy—2nd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 20 September 2025 | Viewed by 603
Special Issue Editor
Interests: biomarkers; therapeutic targets and compounds for Parkinson's disease and other neurodegenerative diseases
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Special Issue Information
Dear Colleagues,
The quality of life of those with peripheral neuropathies is undermined by their various symptoms, such as pain and numbness of the extremities, muscle weakness, and autonomic disorders. The neuropathies are caused by gene mutations, immune system disorders, metabolic abnormalities, cancers and anti-cancer drugs, and other systemic diseases; however, the onset and progression mechanisms remain largely unclear and the efficacious remedies against them have not yet been developed. This Special Issue provides a platform for researchers pursuing the molecular pathogenesis of peripheral neuropathies and novel therapeutic approaches toward them. Detailed information is available from the findings of recent research on inherited neuropathy (e.g., Charcot–Marie–Tooth disease, hereditary ATTR amyloidosis, and Fabry disease), diabetic polyneuropathy, immune-mediated neuropathy (e.g., Guillain–Barré syndrome, chronic inflammatory demyelinating polyneuropathy, and autoimmune autonomic ganglionopathy), and drug-induced neuropathy (e.g., anti-cancer drugs including immune checkpoint inhibitors, amiodarone, and tumor necrosis factor-a antagonists). Basic studies regarding axonal degeneration, demyelination, and neuron–Schwann cell interplay under physiological and pathophysiological conditions are also welcome for submission.
Dr. Zhidong Zhou
Guest Editor
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Keywords
- axonal degeneration
- demyelination
- schwann cells
- dorsal root ganglia
- diabetic neuropathy
- chemotherapy-induced peripheral neuropathies
- immune-mediated neuropathies
- immune checkpoint inhibitors
- charcot-marie-tooth disease
- autonomic neuropathies
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