Novel Extracellular Vesicle-Based Therapy for Central Nervous System Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 20 October 2025 | Viewed by 5762
Special Issue Editor
Interests: extracellular vesicles; biomarker; inflammation; neurological impairment; metabolic dysfunction; intercellular and interorgan crosstalk
Special Issue Information
Dear Colleagues,
The central nervous system (CNS) plays a pivotal role in regulating bodily functions, making the study and treatment of CNS diseases a critical area of research. Extracellular vesicles, including exosomes and microvesicles, have emerged as key players in intercellular communication and the delivery of bioactive molecules. This Special Issue aims to explore the innovative use of EVs as therapeutic agents to target CNS disorders, including neurodegenerative diseases, encephalopathies, mild cognitive impairment, traumatic brain injuries, and neurological cancers.
We welcome submissions of original research manuscripts, short communications, and reviews focusing on the latest advancements in the following areas (the list is not exhaustive): the isolation and characterization of EVs, the cargo of bioactive molecules, mechanisms of action, preclinical and clinical studies, EVs from mesenchymal stem cells (MSCs) and future directions for EV-based therapies in the CNS.
Dr. Andrea Cabrera-Pastor
Guest Editor
Manuscript Submission Information
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Keywords
- extracellular vesicles (EVs)
- exosomes
- therapy
- CNS disorders
- neuroinflammation
- signal transduction
- mechanism
- interorgan crosstalk
- biomarker
- EVs from MSCs
- drug delivery
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