New Insights into β-Subunits of the Sodium-Pump
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: closed (30 April 2024) | Viewed by 282
Special Issue Editor
Interests: Na+/K+-ATPase; β2/AMOG; β1-subunit; cell–cell interaction; protein–protein interaction
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
We would like to invite you to participate in a Special Issue of the International Journal of Molecular Sciences entitled “New Insights into β-Subunits of the Sodium-Pump”.
Na+/K+-ATPases have been studied intensively for nearly 70 years. Nonetheless, they are still at the center of research in various disciplines. In addition to its central role related to the pumping activity of the α-subunit, a wide range of functions are related to the β-subunit of the pump. Initially, the role of the β-subunit of animal Na+/K+-ATPases has been shown as supporting protein folding and stability, as well as serving to occlude bound K+. Both old and emerging information at the molecular level strongly suggest that at least two isoforms of the β-subunit function as cell-adhesion molecules in the epithelia (β1) and as an adhesion molecule on the plasma membrane of astrocytes (β2/AMOG). In this Special Issue, our aim is to publish research and review articles describing the current knowledge and data on the structure–function relationship of the β-subunits of the Na+ pump and on protein–protein interactions that involve β1 and β2 isoforms in homotypic and heterotypic interactions. We are looking for articles that explore the roles played by β-subunits at the molecular, biochemical, physiological, pharmacological, and genetic levels and how they impact the development, normal structure and function, and pathology of epithelial and cerebral tissues.
The scope of this call for papers includes, but is not limited to:
- The structure of β-subunits as components of Na/K-ATPase.
- The role of the β-subunits in modulating the ion transport of Na/K-ATPase.
- The role of β-subunits in targeting the pump to the plasma membrane.
- The adhesive properties of β-subunits in the epithelia and nervous system.
- The participation of β-subunits in neuronal development.
- The relationship between the β-subunits of Na/K-ATPase and cancer.
- Disorders related to the β-subunits of Na/K-ATPase.
- The evolution of β-subunits in P-type ATPases.
Dr. Shoshani Liora
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Na+/K+-ATPase
- β2/AMOG
- β1-subunit
- cell–cell interaction
- protein–protein interaction
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
