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Particles, Vesicles and Small Structures

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".

Deadline for manuscript submissions: closed (25 May 2024) | Viewed by 265

Special Issue Editor

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Guest Editor
1. Department of Medicine and Immunology, Division of Rheumatology and Immunology, Duke University Medical Center, Durham, NC 27710, USA
2. Medical Research Service, Veterans Administration Medical Center, Durham, NC 27705, USA
Interests: immune properties of DNA; immunochemical properties of anti-DNA antibodies; the properties of antinuclear antibodies; the role of DNA in the pathogenesis of systemic lupus erythematosus; the role of microparticles as a source of extracellular DNA; immune properties of HMGB1
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Special Issue Information

Dear Colleagues,

An important focus of current research concerns the unique biological and immunological properties of small structures, also termed particles or vesicles. These structures have diverse origins and can be natural as well as synthetic. Natural particles include bacteria, viruses and fungi as well as extracellular vesicles that emanate from activated and dying cells; natural particles in general have nucleic acid components and provide a vector for transmission of genetic information. In addition, natural particles can contain immunostimulatory molecules such as cytokines. In all cases, small structures that occur naturally concentrate information or bioactive molecules to achieve greater potency, transmissibility and resistance to degradation. Synthetic particles (often called nanoparticles) can vary in biochemical composition and have been designed for in vivo application as novel therapeutic agents where drugs may be encapsulated or displayed on the surface. Like natural particles, synthetic particles have increased biological activity compared to free molecules. Synthetic particles can be "tuned" in terms of their chemistry to have particular activity in the clinical setting, including the ability to target specific cell types.

A special issue will be developed to encompass natural and synthetic nanostructures and include papers on the biology, chemistry, biophysics and pharmacology of small structures. Important cross-cutting themes concern the impact of a particulate structure on extracellular and intracellular trafficking, cell uptake and cell signaling, all of which pertain to both natural and synthetic small structures.

Prof. Dr. David Stephen Pisetsky
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers

There is no accepted submissions to this special issue at this moment.
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