Future Perspectives and Challenges in Molecular Research of Glioma
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 30 June 2025 | Viewed by 367
Special Issue Editor
Special Issue Information
Dear Colleagues,
Gliomas, distinguished by their intricate molecular profiles and heterogeneity, represent the most prevalent primary malignant brain tumors in adults, frequently resulting in unfavorable prognoses and reduced quality of life for patients. Advancements in immunotherapy and imaging techniques have dramatically influenced the study landscape for glioma, especially for the identification of genetic alterations and the enhancement of treatment regimens. Bibliometric analysis has demonstrated that the most cited studies usually signify pioneering contributions to the discipline, especially in glioma immunotherapy.
Notwithstanding these achievements, numerous difficulties persist. The intricacy of gliomas, characterized by their heterogeneity and the existence of a suppressive tumor microenvironment, hampers therapeutic approaches. Moreover, the incorporation of novel medicines into established treatment frameworks necessitates meticulous evaluation of any adverse effects and the overall welfare of patients. Ongoing research, therapeutic trials, and collaboration among oncologists, researchers, and patient advocacy organizations will be crucial in addressing these problems and progressing the field. The integration of modern therapeutic tactics and tailored approaches signifies a new era in glioma molecular research and glioma therapy, promising enhanced patient outcomes and quality of life.
We invite original research, reviews, and preclinical studies that address these topics and help link laboratory discoveries to practical treatments for glioma.
Dr. Shanchun Guo
Guest Editor
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Keywords
- gliomas
- genetic and epigenetic changes
- molecular mechanisms
- immunotherapy
- innovative therapeutic strategies
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