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Antimicrobial, Anti-biofilm and Anti-virulence Activities of Novel Compounds

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".

Deadline for manuscript submissions: 25 July 2024 | Viewed by 444

Special Issue Editors

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Guest Editor
Department of Pharmacy, University “G. d’Annunzio” Chieti-Pescara, 66100 Chieti, Italy
Interests: antimicrobial, anti-biofilm and anti-virulence activities of bioactive substances of natural origin; semi-synthesis and innovative biomaterials; the research activity has concerned oral cavity microorganisms
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Pharmacy, University “G. d’Annunzio” Chieti-Pescara, 66100 Chieti, Italy
Interests: antimicrobial; anti-biofilm and anti-virulence activities of natural compounds alone and combined with antibiotics against multi drug-resistant strains (Helicobacter pylori, Staphylococcus spp., Pseudomonas aeruginosa, Candida albicans, Mycobacterium abscessus and other fast-growing mycobacteria)
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The global prevalence of antibiotic-resistant bacteria has become a very significant concern. Natural products are increasingly investigated as they possess a large array of chemical compounds capable of exhibiting several biological activities such as potent antibacterial and antimicrobial properties.

Natural products also have the capability to affect distinct stages of biofilm formation, such as adhesion, motility, EPS maturation and targeting, as well as microbial virulence factors.

Natural compounds from plants, microbes and animals must be investigated to uncover their full potential as valuable sources to tackle persistent microbial infection.

The aim of this Special Issue is to collect important contributions in the field of natural and synthetic compounds via the investigation of novel antimicrobial, anti-biofilm and anti-virulence activities.

Research areas may include, but not limited to, the following:

  • Study of natural compounds against microorganisms and ones that are multidrug-resistant;
  • Study of anti-biofilm and anti-virulence activities of natural and/or semisynthetic/ synthetic products;
  • Study of combinations of natural compounds and conventional antibiotics/antimicrobials;
  • Study of an innovative delivery system to improve the bioavailability of natural compounds.

In this Special Issue, original research articles and reviews are welcome. I look forward to receiving your contributions.

Dr. Mara Di Giulio
Dr. Silvia Di Lodovico
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • antimicrobial natural compound
  • resistant strains
  • mono- and polymicrobial biofilm
  • synergisms
  • antivirulence natural compounds

Published Papers

This special issue is now open for submission.
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