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Cellular Damage: Protection and Induction

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biophysics".

Deadline for manuscript submissions: closed (10 March 2024) | Viewed by 811

Special Issue Editors

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Guest Editor
Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410013, China
Interests: pharmaceutical engineering; pharmaceutical excipients; crystallization; functional foods; spray drying; micro- and nano-encapsulation
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410013, China
Interests: new drug development; nucleic acid aptamers; disease diagnosis; transdermal drug delivery; multifunctional nanocarriers; pathological mechanism of diseases
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The cell, the essential building block of life, faces a diverse range of molecular biophysical disturbances, including those encountered through chemical and biophysical approaches to cryopreservation. Delving deep into cellular damage and understanding its underlying mechanisms is of utmost importance. At the same time, there is an imperative need to recognize the duality of our approaches: on one hand, safeguarding cells through protective measures, and on the other, purposefully inducing damage, particularly evident in clinical scenarios such as cancer treatments. In this Special Issue, "Cellular Damage: Protection and Induction", we strive to unravel the multifaceted nature of the biophysical damage cells face. Our focus extends to the protective strategies employed via regenerative medicine, pharmacological means, and the nuances of cryopreservation, contrasting them against the deliberate harms, characteristic of treatments like radiation and chemotherapy. We warmly welcome scholars to enrich this issue with their pioneering research and insightful reviews that span across two critical domains: the intricate molecular pathways leading to biophysical cellular disruption and the evolving strategies that either bolster cellular defenses or purposefully target them.

Prof. Dr. Songwen Tan
Prof. Dr. Wenhu Zhou
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • chemical and biophysical approaches to cryopreservation
  • molecular mechanisms of biophysical damage
  • regenerative medicine for cellular protection
  • radiation-induced cellular injuries
  • chemotherapy and targeted cellular damage
  • cellular resilience and recovery pathways
  • intentional cellular disruptions in therapeutic settings
  • environmental and internal triggers of biophysical strain
  • strategies for cellular protection and repair
  • innovations in therapeutic cellular targeting

Published Papers (1 paper)

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3 pages, 200 KiB  
Starting Editorial of “Cellular Damage: Protection and Induction” Addressing Hot Topics in Cellular Damage, Protection of Cells and Therapy Targeting Bad Cells
by Songwen Tan and Wenhu Zhou
Int. J. Mol. Sci. 2023, 24(18), 13702; https://doi.org/10.3390/ijms241813702 - 5 Sep 2023
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The cell, the fundamental unit of life, is constantly subjected to a myriad of molecular biophysical disturbances [...] Full article
(This article belongs to the Special Issue Cellular Damage: Protection and Induction)
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