Molecular Insight into Antimicrobial Resistance
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pharmacology".
Deadline for manuscript submissions: 30 December 2025 | Viewed by 261
Special Issue Editors
Interests: molecular microbiology; bacteriology; antimicrobial resistance; enterococcus; VRE
Special Issue Information
Dear Colleagues,
Antimicrobial resistance (AMR) remains a critical global health threat, driven by complex molecular mechanisms. This Special Issue aims to explore recent advances in understanding the genetic and biochemical basis of resistance in major pathogens, including methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus (VRE), extended-spectrum β-lactamase (ESBL)-producing bacteria, and carbapenem-resistant Enterobacterales (CRE). Of particular interest are emerging resistances such as linezolid resistance in enterococci and reduced susceptibility of Enterobacterales to novel agents and antibiotic combinations. We also welcome studies on resistance to last-resort antimicrobials, horizontal gene transfer, resistance evolution under selective pressure, and molecular surveillance approaches. Contributions involving genomic, transcriptomic, proteomic, or structural insights into AMR mechanisms are encouraged. By shedding light on these molecular underpinnings, this Special Issue aims to inform better therapeutic strategies and guide the development of innovative antimicrobial agents.
Dr. Dan-Alexandru Țoc
Dr. Carmen Costache
Guest Editors
Manuscript Submission Information
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Keywords
- antimicrobial resistance
- MRSA
- ESBL-producing bacteria
- carbapenem-resistant enterobacterales (CRE)
- vancomycin-resistant enterococci (VRE)
- linezolid resistance
- novel antibiotic combinations
- resistance mechanisms
- horizontal gene transfer
- molecular epidemiology
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