Molecular and Translational Research in Cardiovascular Endocrinology, Cardio-Metabolic Diseases and Non-alcoholic Fatty Liver Disease (NAFLD)

Dear Colleagues, 

Cardiovascular tissues have been recognized as dynamic endocrine organs, with vital stimuli that affect the cardiovascular system by acting in an endocrine manner through hormone receptors. Many of these signaling systems are complex and so interconnected that, in many cases, the interlinked components are hard to separate.

Thus, cardiovascular disease, endocrinology, diabetes and metabolism represent closely linked disciplines, giving rise to the field of cardiovascular endocrinology. Moreover, pituitary, adrenal, parathyroid, thyroid and gender hormone excesses or deficiencies, as well as glucose and lipid metabolism disorders, may further impact the risk of cardiovascular disease (e.g., directly or indirectly through atherosclerosis, heart failure and non-alcoholic fatty liver disease (NAFLD)).

Despite the important advances in the field of cardiovascular endocrinology through recent molecular and translational research, there are still open issues regarding the underlying pathogenetic mechanisms, as well as the exact effects/impact of various interventions/treatments, such as lifestyle modification interventions (e.g., dietary and exercise interventions) or pharmacological therapies (e.g., antihypertensive lipid-lowering treatments, antidiabetic drugs , etc.), which may target more than one aspect/factor of cardiometabolic diseases.

This Special Issue, which is edited by Prof. Dr. E. Kassi, As. Prof. Dr. I. Kyrou and Prof. Dr. H.S. Randeva with the aid of our Topical Advisory Panel Member Dr. Narjes Nasiri-Ansari (Department of Biochemistry, Medical School, National and Kapodistrian University of Athens, Greece), focuses on cardiometabolic diseases and endocrine-related cardiovascular diseases, including atherosclerosis, heart failure, arterial hypertension, metabolic syndrome, obesity, diabetes mellitus, chronic kidney disease, NAFLD and dyslipidemia, with topics ranging from the molecular and cellular pathogenetic pathways to novel pharmacological and molecular targets for relevant treatments. Original research articles and reviews on these and related topics are welcome in this Special Issue.

Prof. Dr. Eva Kassi
Dr. Ioannis Kyrou
Prof. Dr. Harpal S. Randeva
Guest Editors

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