Food Microbiome-Driven Personalized Nutrition: Mechanisms, Biomarkers, and Product Development
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".
Deadline for manuscript submissions: 28 February 2026 | Viewed by 3
Special Issue Editor
Interests: intestinal disease; bioactive molecules; gut health; homeostasis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Personalized nutrition is rapidly emerging as a transformative paradigm for promoting optimal health by tailoring dietary recommendations to individual biological, genetic, and lifestyle profiles. Central to this approach is the gut microbiome, a complex and dynamic ecosystem of microorganisms that interacts intimately with dietary components to modulate metabolism, immune function, and systemic health. Growing evidence highlights the microbiome’s critical role in shaping individual responses to foods. This presents a powerful avenue for precision dietary interventions. This Special Issue seeks to advance understanding of the mechanistic pathways linking diet, microbiome composition and activity, and health outcomes, while identifying innovative biomarkers that can guide personalized nutritional strategies. We aim to highlight research spanning fundamental mechanistic studies to translational applications, including the development of microbiome-targeted foods, nutraceuticals, and functional products designed to harness microbial activity for optimizing individual health.
We welcome both original research articles and comprehensive reviews that advance our understanding of microbiome-driven nutrition and its applications. Potential topics for submission include, but are not limited to, the following:
- Mechanistic studies on diet–microbiome–host interactions;
- Identification and validation of microbiome- or metabolite-based biomarkers for personalized nutrition;
- Nutritional interventions targeting microbiome modulation for health benefits;
- Development of functional foods, nutraceuticals, and microbiome-targeted dietary products;
- Advances in -omics technologies (metagenomics, metabolomics, metatranscriptomics) for personalized nutrition;
- Host–microbe interactions influencing metabolic, immune, and cognitive outcomes;
- Microbiome-informed strategies for disease prevention and management;
- Computational and predictive models integrating microbiome and dietary data.
By integrating mechanistic insights with practical applications, this collection seeks to advance the field of microbiome-driven personalized nutrition and support the translation of scientific discoveries into tailored, evidence-based dietary solutions.
Prof. Dr. Wolfram Manuel Brück
Guest Editor
Manuscript Submission Information
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Keywords
- personalized nutrition
- gut microbiome
- health outcomes
- biomarkers
- functional foods
- metagenomics
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