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Special Issue "Drug Delivery and Scaffolding in the Era of 3D-Printing and Microfluidic Techniques: Challenges and Opportunities 2.0"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Materials Science".

Deadline for manuscript submissions: 20 September 2021.

Special Issue Editors

Prof. Dr. Ida Genta
E-Mail Website1 Website2
Guest Editor
Department of Drug Sciences, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy
Interests: drug delivery; polymer nanoparticles; microspheres; biodegradable polymers; thermosensitive hydrogel; 3D bioprinting; tissue regeneration
Special Issues and Collections in MDPI journals
Prof. Dr. Bice Conti
E-Mail Website
Guest Editor
Department of Drug Sciences, Lab. Pharmaceutical Technology and Law (PT&L), University of Pavia, Pavia, Italy
Interests: drug delivery; polymer nanoparticles; microspheres; biodegradable polymers; thermosensitive hydrogels; 3D bioprinting; tissue regeneration
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue is a continuation of our previous Special Issue “Drug Delivery and Scaffolding in the Era of 3D-Printing and Microfluidic Techniques: Challenges and Opportunities” (https://www.mdpi.com/journal/ijms/special_issues/3D_printing_tech).

In the era of precision medicine, the development of new diagnostic and therapeutic approaches is being reached through the development of even more sophisticated pharmaceutical systems. In combination with the explosion of biomolecule discoveries and the knowledge of physiological and pathological pathways, pharmaceutical system applications have extended to the selective delivery of drugs and genetic materials (i.e. selective nanocarriers, manipulated with multifunctionality, also exploitable for theranostic purposes, and polymeric scaffolds used to tune drug or biomolecule delivery) and to cell delivery (i.e. polymeric scaffolds where the scaffold material and structure, cells and bioactive molecules interact for tissue engineering or regenerative medicine). To date, there has been a discrepancy between the amount of research devoted to the topic and its translation to patients, due to the fact that pharmaceutical systems are often quite sophisticated in their design, difficult both to reliably and reproducibly manufacture and to characterize from a pharmaceutical and toxicological viewpoint.

Confident in the utility of new technological approaches in helping the clinical translation of innovative drug delivery systems, this Special Issue is aimed at highlighting the impact and challenges of the most recent technology in the development of more cost-effective, as well as patient-friendly, drug delivery systems.

Suggested topic are: 3D-printing; 3D-bio-printing; electrospinning; injection molding and combinations thereof for scaffold development or for formulative development; microfluidics techniques for nanocarrier preparation; continuous manufacturing of pharmaceuticals; regulatory approaches to innovative technologies.

Prof. Dr. Ida Genta
Prof. Dr. Bice Conti
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • 3D printing
  • 3D bio-printing
  • electrospinning
  • microfluidics
  • injection molding
  • continuous manufacturing
  • regulatory approaches to innovative technologies in pharmaceutical field

Published Papers (1 paper)

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Review

Review
Fabrication and Applications of Microfluidic Devices: A Review
Int. J. Mol. Sci. 2021, 22(4), 2011; https://doi.org/10.3390/ijms22042011 - 18 Feb 2021
Cited by 4 | Viewed by 1291
Abstract
Microfluidics is a relatively newly emerged field based on the combined principles of physics, chemistry, biology, fluid dynamics, microelectronics, and material science. Various materials can be processed into miniaturized chips containing channels and chambers in the microscale range. A diverse repertoire of methods [...] Read more.
Microfluidics is a relatively newly emerged field based on the combined principles of physics, chemistry, biology, fluid dynamics, microelectronics, and material science. Various materials can be processed into miniaturized chips containing channels and chambers in the microscale range. A diverse repertoire of methods can be chosen to manufacture such platforms of desired size, shape, and geometry. Whether they are used alone or in combination with other devices, microfluidic chips can be employed in nanoparticle preparation, drug encapsulation, delivery, and targeting, cell analysis, diagnosis, and cell culture. This paper presents microfluidic technology in terms of the available platform materials and fabrication techniques, also focusing on the biomedical applications of these remarkable devices. Full article
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