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Molecular Mechanisms of Immunotherapy in Cancer

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".

Deadline for manuscript submissions: 31 August 2025 | Viewed by 52

Special Issue Editor


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Guest Editor
Center of Cellular Immunotherapy, Warsaw University of Life Sciences, J. Ciszewskiego 8, b. 23, 02-786 Warsaw, Poland
Interests: macrophage cells; cell-based therapies; immunology; tumor microenvironment
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Special Issue Information

Dear Colleagues,

Immunotherapy has revolutionized cancer treatment by harnessing the power of the immune system to recognize and eliminate tumor cells. Various immunotherapeutic approaches, including immune checkpoint inhibitors, chimeric antigen receptor (CAR) T-cell therapy, monoclonal antibodies, and adoptive macrophage therapies, have demonstrated remarkable pre-clinical and clinical success. However, challenges such as immune evasion, tumor microenvironment modulation, and therapy resistance still need to be addressed to improve treatment efficacy. 

This Special Issue focuses on the molecular mechanisms underlying immunotherapy in cancer. Understanding the interactions between immune cells, tumor cells, and the surrounding microenvironment will provide insights into novel therapeutic strategies and biomarkers for predicting treatment response. We invite researchers to submit original research articles and reviews covering topics such as immune cell engineering, cytokine signaling, metabolic regulation in the tumor microenvironment, and innovative combination therapies. 

We look forward to your valuable contributions to advancing the field of cancer immunotherapy.

Prof. Dr. Magdalena Król
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cancer immunotherapy
  • tumor microenvironment
  • immune checkpoint inhibitors
  • monoclonal antibodies
  • cytokine signaling
  • tumor immune evasion
  • metabolic regulation in cancer
  • cell-based therapies

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Published Papers

This special issue is now open for submission.
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