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Pluripotent Nucleic Acids and Nanomaterials
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Pluripotent Nucleic Acids and Nanomaterials

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".

Deadline for manuscript submissions: closed (30 June 2024) | Viewed by 8771

Special Issue Editors

Dr. Longjiao Zhu

E-Mail Website
Guest Editor
Department of Nutrition and Health, China Agricultural University, No. 10, Tianxiu Road, Beijing 100193, China
Interests: functional nucleic acids; nanomaterial; food safety; nutrition
Special Issues, Collections and Topics in MDPI journals
Dr. Nan Cheng

E-Mail Website
Guest Editor
College of Food Science and Nutritional Engineering, China Agricultural University, No. 17, Tsinghua East Road, Beijing 100083, China
Interests: biosensing technology for rapid and sensitive detection of food safety risk factors; nanotechnology for bio-applications; intelligent and 3D-printed devices integration
Special Issues, Collections and Topics in MDPI journals
Dr. Jingjing Tian

E-Mail Website
Guest Editor
Key Laboratory of Food Processing and Quality Control, College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China
Interests: synthesis biology; molecular biology; functional nucleic acids; biosensor
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Structure determines function. Due to the richness of sequence composition and the complexity of chemical bonds and forces between microscopic atoms and molecules, a variety of nucleic acid structures and their conformations have been discovered, which give the nucleic acid-specific recognition, stimulus response, assembly controllability, luminous properties, antibacterial properties, enzyme catalysis and other pluripotent. Additionally, the components and sequences of nucleic acids also provide these with programmability, tailoring, modifiability, and biocompatibility. Due to their special size effect, nanomaterials also show rich interfacial properties, enzyme-like activities, fluorescence and other forms of pluripotency. The cross-fusion of the two is of great significance for the co-detection of multiple types of food safety risk factors and nutritional efficacy factors, as well as the efficient, stable encapsulation and targeted delivery of food nutritional efficacy components. In addition, other new cross innovation fields and topics, such as bacteriostasis, imaging, diagnosis, and therapy are also very welcome for submission to this Special Issue.

Dr. Longjiao Zhu
Dr. Nan Cheng
Dr. Jingjing Tian
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nucleic acids
  • nanomaterial
  • food safety
  • nutrition
  • biosensing
  • encapsulation
  • delivery
  • diagnosis
  • therapy
  • imaging
  • bacteriostasis

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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Review

39 pages, 7864 KiB  
Review
Recent Advances in Nanozyme-Mediated Strategies for Pathogen Detection and Control
by Tianyi Ma, Kunlun Huang and Nan Cheng
Int. J. Mol. Sci. 2023, 24(17), 13342; https://doi.org/10.3390/ijms241713342 - 28 Aug 2023
Cited by 14 | Viewed by 3934
Abstract
Pathogen detection and control have long presented formidable challenges in the domains of medicine and public health. This review paper underscores the potential of nanozymes as emerging bio-mimetic enzymes that hold promise in effectively tackling these challenges. The key features and advantages of [...] Read more.
Pathogen detection and control have long presented formidable challenges in the domains of medicine and public health. This review paper underscores the potential of nanozymes as emerging bio-mimetic enzymes that hold promise in effectively tackling these challenges. The key features and advantages of nanozymes are introduced, encompassing their comparable catalytic activity to natural enzymes, enhanced stability and reliability, cost effectiveness, and straightforward preparation methods. Subsequently, the paper delves into the detailed utilization of nanozymes for pathogen detection. This includes their application as biosensors, facilitating rapid and sensitive identification of diverse pathogens, including bacteria, viruses, and plasmodium. Furthermore, the paper explores strategies employing nanozymes for pathogen control, such as the regulation of reactive oxygen species (ROS), HOBr/Cl regulation, and clearance of extracellular DNA to impede pathogen growth and transmission. The review underscores the vast potential of nanozymes in pathogen detection and control through numerous specific examples and case studies. The authors highlight the efficiency, rapidity, and specificity of pathogen detection achieved with nanozymes, employing various strategies. They also demonstrate the feasibility of nanozymes in hindering pathogen growth and transmission. These innovative approaches employing nanozymes are projected to provide novel options for early disease diagnoses, treatment, and prevention. Through a comprehensive discourse on the characteristics and advantages of nanozymes, as well as diverse application approaches, this paper serves as a crucial reference and guide for further research and development in nanozyme technology. The expectation is that such advancements will significantly contribute to enhancing disease control measures and improving public health outcomes. Full article
(This article belongs to the Special Issue Pluripotent Nucleic Acids and Nanomaterials)
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23 pages, 2626 KiB  
Review
Research Progress of Nucleic Acid Detection Technology for Genetically Modified Maize
by Tongyun Luo, Lujing Li, Shirui Wang and Nan Cheng
Int. J. Mol. Sci. 2023, 24(15), 12247; https://doi.org/10.3390/ijms241512247 - 31 Jul 2023
Cited by 8 | Viewed by 3714
Abstract
Genetically modified (GM) maize is one of the earliest GM crops to have achieved large-scale commercial cultivation globally, and it is of great significance to excel in the development and implementation of safety policy regarding GM, and in its technical oversight. This article [...] Read more.
Genetically modified (GM) maize is one of the earliest GM crops to have achieved large-scale commercial cultivation globally, and it is of great significance to excel in the development and implementation of safety policy regarding GM, and in its technical oversight. This article describes the general situation regarding genetically modified maize, including its varieties, applications, relevant laws and regulations, and so on. From a technical point of view, we summarize and critically analyze the existing methods for detecting nucleic acid levels in genetically modified maize. The nucleic acid extraction technology used for maize is explained, and the introduction of traditional detection techniques, which cover variable-temperature and isothermal amplification detection technology and gene chip technology, applications in maize are described. Moreover, new technologies are proposed, with special attention paid to nucleic acid detection methods using sensors. Finally, we review the current limitations and challenges of GM maize nucleic acid testing and share our vision for the future direction of this field. Full article
(This article belongs to the Special Issue Pluripotent Nucleic Acids and Nanomaterials)
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