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Genes publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Genetic Mutations and Molecular Mechanisms in Human Diseases

edited by Ying Chen Claire Hou and Mariam Mathew

submission deadline 25 May 2026 | Viewed by 75 | Submission Open

Keywords: genetics; cytogenetics; genome sequencing; RNA sequencing; functional genomics; precision medicine; epigenetics; DNA methylation; single-cell technologies; spatial omic technologies; human diseases

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Plant Responses to Abiotic Stress: Genetics, Transcription, Noncoding RNAs, and Epigenetics

edited by Runlai Hang

submission deadline 25 May 2026 | Viewed by 73 | Submission Open

Keywords: abiotic stress responses; LncRNA; RNA biology; translation; miRNA; siRNA; rRNA; epigenetics; DNA methylation; RNA modification

(This special issue belongs to the Section Plant Genetics and Genomics)

Genetics of Head and Neck Disorders

edited by Christos Yapijakis

submission deadline 25 May 2026 | Viewed by 47 | Submission Open

Keywords: head and neck pathology; craniofacial genetics; orofacial genetics; developmental genetics; neurogenetics; cancer genetics; genomics and gene variation; epigenetics; personalized medicine and dentistry; genetic counseling and ethics

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Genetic, Epigenetic and Environmental Factors in Dental Development and Pathologies: Genes, Interactions and Dental Development

edited by

Alan H. Brook

submission deadline 5 Jun 2026 | 17 articles | Viewed by 57477 | Submission Open

Keywords: dental development; genetics; epigenetics; complex adaptive systems; interactive networks

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Genes and Pediatrics

edited by

Giorgia Ceravolo

and

Roberto Chimenz

submission deadline 5 Jun 2026 | 2 articles | Viewed by 3160 | Submission Open

Keywords: pediatric disease; genetic variant; clinical observation; diagnosis; patient care

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Genetic Biomarkers in Cancer: From Discovery to Clinical Application

edited by

Evangelos Koustas

submission deadline 5 Jun 2026 | 1 articles | Viewed by 1225 | Submission Open

Keywords: cancer; tumor biology; biomarkers; cancer therapy; targeted therapy

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

The Genetics of Male Infertility and Clinical Implications

edited by

Gianmaria Salvio

submission deadline 5 Jun 2026 | 1 articles | Viewed by 843 | Submission Open

Keywords: genetics; male infertility; azoospermia; next generation sequencing; genetic variants

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Genetic Mechanisms of Plant Resistance to Biotic Stress

edited by

Zhuo Chen

submission deadline 5 Jun 2026 | Viewed by 151 | Submission Open

Keywords: plant diseases; biotic stress; resistance genes; genetics; genomics; plant hosts

(This special issue belongs to the Section Plant Genetics and Genomics)

Genetics and Epidemiology of Parasites

edited by

Joanna Da̧browska

submission deadline 10 Jun 2026 | 1 articles | Viewed by 925 | Submission Open

Keywords: parasite genetics; parasite genomics; WGS; molecular epidemiology; zoonoses; virulence and pathogenesis; transmission dynamics; genetic diversity

(This special issue belongs to the Section Microbial Genetics and Genomics)

Genetic Basis of Pig Breeding and Regulation of Meat Production Efficiency and Quality Control

edited by

Mailin Gan

and Liyuan Shen

submission deadline 10 Jun 2026 | Viewed by 92 | Submission Open

Keywords: pig; meat; molecular mechanism; multi-omics; production efficiency

(This special issue belongs to the Section Animal Genetics and Genomics)

Genetics of Substance Use and Addictions

edited by

Eric R. Braverman

submission deadline 10 Jun 2026 | Viewed by 28 | Submission Open

Keywords: genetics of addiction; substance use disorders; dopamine; catecholamines; polygenic risk; epigenetics; neuroendocrine regulation; deep phenotyping; reward deficiency syndrome; GARS; gene– phenotype classification

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Genetics and Genomics of Autism Spectrum Disorders

edited by

Roberto Canitano

and

Marco Carotenuto

submission deadline 15 Jun 2026 | 1 articles | Viewed by 1290 | Submission Open

Keywords: autism spectrum disorders; genetics; new techniques for diagnosis

(This special issue belongs to the Section Neurogenomics)

Research Updates in Forensic Genetics

edited by Massimo Lancia

submission deadline 15 Jun 2026 | 2 articles | Viewed by 1117 | Submission Open

Keywords: next generation sequencing; single cell analysis; time since deposition; time since death; DNA phenotyping; biogeographic ancestry; age prediction; familial search; disaster victim identification; trace DNA contextualisation

(This special issue belongs to the Section Molecular Genetics and Genomics)

Targeting RNA Coding Mechanisms in Disease Molecular Pathways

edited by

Wangyong Yang

submission deadline 15 Jun 2026 | Viewed by 173 | Submission Open

Keywords: RNA therapeutics; RNA modifications (epitranscriptomics); non-coding RNA (ncRNA); alternative splicing; RNA-binding proteins (RBPs); RNA-targeted small molecules; gene therapy; molecular pathways; disease biomarkers; RNA vaccines

(This special issue belongs to the Section RNA)

Genetics and Breeding of Forage—2nd Edition

edited by Maofeng Chai

submission deadline 15 Jun 2026 | Viewed by 30 | Submission Open

Keywords: forage genetic improvement; molecular breeding; abiotic stress; biotic stress; population genetics; multi-omics analysis; nutrition absorption

(This special issue belongs to the Section Plant Genetics and Genomics)

Genetics and Genomics in Cancer

edited by

Rina Kansal

submission deadline 20 Jun 2026 | Viewed by 218 | Submission Open

Keywords: solid tumors; breast cancer; colon cancer; lung cancer; prostate cancer; gastrointestinal; gynecologic cancer; genitourinary cancers; brain tumors; hematolymphoid neoplasms; myeloid neoplasms; lymphoid neoplasms; hereditary cancer; precision medicine

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Research on Genetics and Breeding of Rice

edited by Xiaojin Luo

submission deadline 20 Jun 2026 | Viewed by 208 | Submission Open

Keywords: rice breeding; molecular genetics; rice germplasm; QTL identification and gene cloning; genetic function and genetic network; breeding technologies

(This special issue belongs to the Section Plant Genetics and Genomics)

Advancements in Pharmacogenomics for Precision Medicine

edited by

Óscar Teijido Hermida

submission deadline 20 Jun 2026 | Viewed by 82 | Submission Open

Keywords: pharmacogenomics; precision medicine; pharmacoepigenomics; epidrugs; genomic biomarkers; drug response variability; personalized therapy; multi-omics integration; pharmacogenetic testing; clinical implementation; artificial intelligence in pharmacogenomics; genetic polymorphisms; translational genomics

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Advances in Genomic Surveillance of Pathogens

edited by Rachel R. Spurbeck

submission deadline 20 Jun 2026 | Viewed by 2 | Submission Open

Keywords: biosurveillance; pathogen detection; host response; epigenomics; genomics; transcriptomics; viromics; microbiome analysis; shotgun metagenomics

(This special issue belongs to the Section Microbial Genetics and Genomics)

The CranioFacial Biology Group at the University of Adelaide Collection: Genetic, Epigenetic and Environmental Factors in Complex Adaptive Systems, Multilayer Complex Interactive Networks, and Multiple Models During Oral Development

edited by

Alan H. Brook

and Matthew Brook O'Donnell

submission deadline 25 Jun 2026 | 2 articles | Viewed by 3197 | Submission Open

Keywords: oral development; genetics; epigenetics; complex adaptive systems; multilayer complex interactive networks; multiple models

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Insights into the Genomic and Genetic Basis of Cardiovascular Disease

edited by Marzia de Biasio and

Donato Gemmati

submission deadline 25 Jun 2026 | 2 articles | Viewed by 1319 | Submission Open

Keywords: recurrent idiopathic pericarditis and perimyocarditis; spontaneous coronary dissection; sudden idiopathic cardiac death; idiopathic atrial fibrillation; cardio-oncology and cardio toxicity of anti anti-cancer drugs

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Plant Pathogenic Fungi: Molecular Systematics, Genomics and Evolution

edited by

Shengxiong Huang

submission deadline 25 Jun 2026 | Viewed by 85 | Submission Open

Keywords: plant pathogenic fungi; pathogen isolation and identification; molecular evolution; multi-omics analysis; genome sequencing; comparative genomics; RNA-seq

(This special issue belongs to the Section Plant Genetics and Genomics)

Genomic and Transcriptomic Advances in Amyotrophic Lateral Sclerosis (ALS) and Motor Neuron Diseases (MND)

edited by

Francesca Dragoni

and

Stella Gagliardi

submission deadline 5 Jul 2026 | Viewed by 178 | Submission Open

Keywords: ALS ; transcriptomic studies ; motor neuron diseases ; biomarkers assessment ; pathomechanisms ; genetics ; genotype– phenotype correlation

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Advances in Molecular Genetics of Rare Disorders

edited by Miriam Lucia Carriero

submission deadline 10 Jul 2026 | Viewed by 33 | Submission Open

Keywords: rare diseases; molecular genetics; gene– disease associations; genotype– phenotype correlation; targeted gene therapy; next-generation sequencing; whole-genome sequencing; genome-wide association studies; functional genomics

(This special issue belongs to the Section Molecular Genetics and Genomics)

Genetic and Molecular Insights into Migraine

edited by Maria Papasavva and Vasileios Siokas

submission deadline 15 Jul 2026 | Viewed by 101 | Submission Open

Keywords: neurosciences; neurology; neurogenetics; molecular neurology; neurodegeneration; neurorehabilitation; rTMS

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Genetic and Epigenetic Mechanisms in Animal Reproduction

edited by Ming Shen

submission deadline 15 Jul 2026 | Viewed by 41 | Submission Open

Keywords: animal reproduction; genetic regulation; epigenetic modification; DNA methylation; histone modification; noncoding rna; chromatin remodeling; gametogenesis; fertilization; embryonic development; reproductive efficiency; reproductive disorders; gene expression; livestock breeding; reproductive biotechnology

(This special issue belongs to the Section Animal Genetics and Genomics)

Genetics and Genomics of Plant Reproductive Development

edited by

Pingli Lu

submission deadline 20 Jul 2026 | Viewed by 103 | Submission Open

Keywords: genetics; genomics; meiosis; anther development; gametophyte development; fertilization; seed; fruit

(This special issue belongs to the Section Plant Genetics and Genomics)

Fetal Genetic Disorders: Diagnosis and Therapy

edited by Gianluca Campobasso

submission deadline 20 Jul 2026 | Viewed by 103 | Submission Open

Keywords: fetal medicine; malformations; ; genetic anomalies; ; genomic sequencing; ; syndromes; artificial intelligence

(This special issue belongs to the Section Genetic Diagnosis)

Environmental Genomics and Low-Dose Induced Adaptive Response: Underlying Mechanisms from Cells to Organisms

edited by Stephka Chankova, Michaela Beltcheva and

Teodora Todorova

submission deadline 20 Jul 2026 | Viewed by 19 | Submission Open

Keywords: environmental genomics; ecotoxicology; low-dose induced adaptive response; low-dose radiation; genomic instability; environmental mutagenesis; DNA repair; radio-protection; stress response; toxicogenomics; antioxidant system; chaperone system

(This special issue belongs to the Section Genes & Environments)

Genetics and Diagnosis of Colorectal Cancer

edited by

Shiki Fujino

submission deadline 10 Aug 2026 | Viewed by 95 | Submission Open

Keywords: colorectal cancer; genetics; diagnosis; biomarkers; molecular profiling; cancer stem cell

(This special issue belongs to the Section Genetic Diagnosis)

Buffalo Genetics and Genomics

edited by

Qingyou Liu

and Laiba Shafique

submission deadline 15 Aug 2026 | 4 articles | Viewed by 7637 | Submission Open

Keywords: buffaloes; ruminant; genomics; genetics; evolution; structural characterization

(This special issue belongs to the Section Animal Genetics and Genomics)

Genomic and Molecular Determinants of HPV-Related Reproductive Health

edited by

Nektaria Zagorianakou

and

Efthalia Moustakli

submission deadline 15 Aug 2026 | Viewed by 92 | Submission Open

Keywords: human papillomavirus (HPV); viral genomics; epigenomics; proteomics; vaginal microbiome; intestinal microbiome; metabolic pathways; oxidative stress; infertility genetics; reproductive health; personalized medicine; precision medicine; AI-driven diagnostics

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Hereditary Traits and Diseases in Companion Animals

edited by

Lucie Chevallier

and

Marie Abitbol

submission deadline 25 Sep 2026 | 3 articles | Viewed by 3063 | Submission Open

Keywords: genetic traits; hereditary diseases; companion animals; spontaneous disease models; veterinary genetics; genetic selection; breed-specific diseases

(This special issue belongs to the Section Animal Genetics and Genomics)

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