Genetics and Genomics in Cancer
A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Human Genomics and Genetic Diseases".
Deadline for manuscript submissions: 20 June 2026 | Viewed by 1031
Special Issue Editor
2. Department of Pathology and Anatomical Sciences, The University at Buffalo, Buffalo, NY, USA
Interests: hematopathology; hematology; molecular genetics; anatomic pathology; clinical pathology; cancer
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Scientific advances in genetics and genomics related to cancer are among the most important achievements of the 21st century, impacting how we diagnose and treat human diseases. These breakthroughs primarily led to the era of precision medicine in cancer, enabling accurate diagnosis, prognosis assessment, and targeted therapies for both hematologic and non-hematologic cancers. Cancer has been the second leading cause of death worldwide from 1990 to 2023, except in 2021, when respiratory infections caused more deaths. According to the Global Burden of Cancer 2023 study, an estimated 18.5 million new cancer cases and 10.4 million cancer-related deaths occurred in 2023, including non-melanoma skin cancers. These numbers are expected to increase through 2050, especially in low-resource regions experiencing disproportionate rises in new cases and fatalities. In both males and females combined, the highest burden of new cancer cases was due to (1) breast cancer, (2) tracheal, bronchial, and lung cancers, and (3) colon and rectal cancers, each with about 2.3 million cases, followed by prostate cancer (1.41 million) and stomach cancer (1.26 million). Tracheal, bronchus, and lung cancers accounted for the highest number of deaths (2.04 million), followed by colon and rectum cancers (1.11 million), stomach cancer (935,000), breast cancer (778,000), and esophageal cancer (577,000). Between 1990 and 2023, age-standardized mortality rates from cancer decreased by 23%. However, this decline was only observed in upper-middle-income and high-income groups, while lower-income groups saw an increase in age-standardized mortality rates, emphasizing the need for global healthcare equity. This Special Issue invites articles on any aspect of genetics and genomics related to any cancer.
Dr. Rina Kansal
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- solid tumors
- breast cancer
- colon cancer
- lung cancer
- prostate cancer
- gastrointestinal, gynecologic cancer
- genitourinary cancers
- brain tumors
- hematolymphoid neoplasms
- myeloid neoplasms
- lymphoid neoplasms
- hereditary cancer
- precision medicine
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