Genomic and Transcriptomic Advances in Amyotrophic Lateral Sclerosis (ALS) and Motor Neuron Diseases (MND)

A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Human Genomics and Genetic Diseases".

Deadline for manuscript submissions: 5 July 2026 | Viewed by 110

Special Issue Editors


E-Mail Website
Guest Editor
Molecular Biology and Transcriptomics Unit, IRCCS Mondino Foundation, 27100 Pavia, Italy
Interests: neurosciences; molecular biology; transcriptomics; neuromuscular disease; biomarkers

E-Mail Website
Guest Editor
Molecular Biology and Transcriptomics Unit, IRCCS Mondino Foundation, 27100 Pavia, Italy
Interests: amyotrophic lateral sclerosis (ALS); coding and non-coding RNA; gene expression; neurodegenerative diseases; genetic
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues, 

Amyotrophic Lateral Sclerosis (ALS) and other Motor Neuron Diseases (MNDs) are devastating neurodegenerative conditions characterized by progressive motor neuron loss. Despite significant advancements, the underlying pathomechanisms remain largely elusive, hindering the development of effective treatments and reliable biomarkers. This Special Issue aims to gather cutting-edge research to illuminate these complex diseases.

Building upon recent breakthroughs in molecular biology and high-throughput technologies, we invite submissions focusing on transcriptomics, methylation analysis, genotype–phenotype characterization, biomarker discovery, and the elucidation of disease pathomechanisms in ALS and MNDs. We welcome both original research articles and comprehensive review articles that contribute to a deeper understanding of these conditions. Our goal is to foster a collaborative platform for disseminating novel findings and accelerating therapeutic strategies.

Dr. Francesca Dragoni
Dr. Stella Gagliardi
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • ALS 
  • transcriptomic studies 
  • motor neuron diseases 
  • biomarkers assessment 
  • pathomechanisms 
  • genetics 
  • genotype–phenotype correlation

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers

This special issue is now open for submission.
Back to TopTop