Genetics and Diagnosis of Colorectal Cancer
A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Genetic Diagnosis".
Deadline for manuscript submissions: 10 August 2026
Special Issue Editor
Interests: colorectal cancer; cancer stem cell; biomarker; prediction model; CTC; liquid biopsy; tumor microenvironment; early-onset colorectal cancer; treatment outcomes
Special Issue Information
Dear Colleagues,
Colorectal cancer remains one of the leading causes of cancer-related mortality worldwide and continues to challenge clinicians and researchers due to its marked biological and clinical heterogeneity. Advances in sequencing technologies and molecular profiling have significantly expanded our understanding of the genetic determinants of colorectal tumor initiation and progression. At the same time, efforts to integrate tumor biology with innovative diagnostic strategies have highlighted the importance of identifying biomarkers that capture both genetic alterations and functional phenotypes shaped by tumor heterogeneity, stem cell dynamics, and microenvironmental influences. As precision medicine evolves, translational research that connects molecular discoveries with clinically actionable diagnostic tools is essential.
This Special Issue of Genes, titled “Genetics and Diagnosis of Colorectal Cancer”, aims to bring together high-quality work across the spectrum of genetic research and diagnostic development. We welcome original studies, reviews, commentaries, and methodological innovations focused on gene mutations, genomic and transcriptomic profiling, liquid biopsy applications, molecular pathology, early detection technologies, AI-assisted diagnostics, and multiomics approaches with clinical relevance. Submissions addressing early-onset colorectal cancer, hereditary syndromes, and preclinical models that inform diagnostic practice are also encouraged.
Dr. Fujino Shiki
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- colorectal cancer
- genetics
- diagnosis
- biomarkers
- molecular profiling
- cancer stem cell
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