Environmental Genomics and Low-Dose Induced Adaptive Response: Underlying Mechanisms from Cells to Organisms
A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Genes & Environments".
Deadline for manuscript submissions: 20 July 2026 | Viewed by 19
Special Issue Editors
Interests: low-dose adaptive response (AR); the contribution of DNA repair; antioxidant and chaperone systems for the formation of an AR; genotypes and induced resistance; screening of genotoxics; mutagenic effects of environmental pollutants; lower eukaryotes; higher plants; anti-mutagenesis
Interests: small mammals; eco-toxicology; eco-physiology; adaptive responses at different levels of biological organization to various environmental pollutants
Interests: mutagenesis/antimutagenesis; anticarcinogenesis; oxidative stress; natural products; low-dose adaptive response; mechanisms of DSBs induction and repair; Ty1 retrotransposition; genome stability
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Special Issue Information
Dear Colleagues,
We are pleased to announce the launch of the Special Issue "Environmental Genomics and Low-Dose Induced Adaptive Response: Underlying Mechanisms from Cells to Organisms". This Special Issue calls for original research and reviews that explore the genomic and molecular foundations of adaptive responses triggered by low-dose exposure to environmental stressors, including radiation and genotoxic chemicals. The central focus is on the phenomenon of induced resistance (the adaptive response), a critical radio-protective mechanism formally recognized by the International Atomic Energy Agency and the World Health Organization for its implications in human and environmental health. We welcome contributions that use cutting-edge environmental genomics, mutagenesis screening, epigenomics, and molecular techniques to decipher the signaling pathways that enable this protection—from activation of DNA repair, as well as antioxidant and chaperone defenses, to systemic organismal resilience. At higher levels of biological organization, the submission of eco-toxicological research is encouraged, particularly research focused on how low-dose environmental stressors shape whole organisms’ physiology, fitness, and adaptive resilience in natural or experimental populations. This collection aims to synthesize knowledge about the dual aspects of environmental mutagenesis and the low-dose induced adaptive response, ultimately improving our understanding of the mechanisms of biological defense and informing environmental risk assessment and public health strategies.
Prof. Dr. Stephka Chankova
Dr. Michaela Beltcheva
Dr. Teodora Todorova
Guest Editors
Manuscript Submission Information
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Keywords
- environmental genomics
- ecotoxicology
- low-dose induced adaptive response
- low-dose radiation
- genomic instability
- environmental mutagenesis
- DNA repair
- radio-protection
- stress response
- toxicogenomics
- antioxidant system
- chaperone system
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