Development and Application of Biosensors in the Food Field

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Food Analytical Methods".

Deadline for manuscript submissions: 25 May 2025 | Viewed by 1984

Special Issue Editors


E-Mail Website
Guest Editor
School of Food Science and Engineering, Hainan University, No. 58 Renmin Avenue, Haikou, China
Interests: flexible sensor; textiles; funtional polymer composites
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, China
Interests: molecular imprinting technology; surface-enhanced Raman scattering; membranes
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor Assistant
Analysis and Testing Center, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China
Interests: food analysis; biosensor; food safety; analytical methods

Special Issue Information

Dear Colleagues,

In the field of food science and safety, the advent of biosensors has revolutionized the way we detect and monitor contaminants, nutrients, and other critical analytes. Foods is pleased to introduce this Special Issue, which aims to present the latest advancements, innovative applications, and future perspectives of biosensors in the food industry. This compilation of research articles and reviews will provide a comprehensive overview of innovations in biosensor development and their implementation in the enhancement of food safety, quality, and nutrition.

Biosensors, due to their high sensitivity, specificity, and rapid response, have become indispensable tools for real-time monitoring and on-site testing in the food sector. They offer a viable alternative to traditional analytical methods, which are often labor-intensive, time-consuming, and require sophisticated equipment. The integration of biological recognition elements with transducing components has enabled the creation of portable devices that can detect a wide array of targets, from mycotoxins and pesticides to nutrients and pathogens, with unparalleled precision.

This Special Issue compiles a diverse array of contributions that highlight the multidisciplinary nature of biosensor research. We welcome the submission of original research articles that present groundbreaking findings regarding the development of novel biosensors for the detection of foodborne pathogens and toxins, as well as review articles that provide in-depth analyses of existing technologies and their applications. This Special Issue also features perspectives on challenges and opportunities in the field, including discussions on sensor stability, reproducibility, and the integration of biosensors with digital platforms for data analysis and interpretation.

We invite you to explore the cutting-edge research and thought-provoking discussions within this Special Issue, and we hope that the insights gained will inspire further advancements in the field of biosensor technology for the food sector. Manuscripts should be submitted through the journal's online submission system and will undergo rigorous peer review.

Scope of the Special Issue:

The scope of this Special Issue includes, but is not limited to, the following topics:

  • Novel Biosensor Technologies: Innovations in biosensor design, including the use of new materials, nanotechnology, and microfluidics for enhanced sensitivity and specificity.
  • Detection of Foodborne Pathogens: The development of biosensors for the rapid detection and identification of bacteria, viruses, and other pathogens in food products.
  • Mycotoxin and Pesticide Detection: Biosensors for monitoring mycotoxins and pesticide residues in agricultural products and foodstuffs.
  • Food Allergen Detection: Innovative biosensors for the detection of allergenic substances in food to ensure safety for consumers with allergies.
  • Nutrient Analysis: Applications of biosensors in the analysis of nutrients, such as vitamins, minerals, and macronutrients, for quality control and nutritional labeling.
  • Food Adulteration and Authentication: The use of biosensors to detect adulteration and authenticate the origin of food products, including detection of counterfeit ingredients.
  • Environmental Monitoring in Food Production: Biosensors for monitoring environmental parameters in food production areas, such as water quality and air contaminants.
  • Food Safety and Quality Control: The implementation of biosensors in food processing facilities for real-time monitoring of safety and quality parameters.
  • Portable and On-Site Biosensors: Development of portable biosensing devices for on-site testing in field conditions, such as farms, processing plants, and retail environments.
  • Data Integration and Digital Platforms: The integration of biosensors with digital platforms for data collection, analysis, and real-time decision-making in the food supply chain.
  • Regulatory Aspects and Standards: Discussion on the regulatory frameworks, standards, and guidelines that govern the use of biosensors in food safety and quality assessment.
  • Challenges and Future Perspectives: Analysis of current challenges faced in the field, such as sensor stability, reproducibility, and cost-effectiveness, along with future directions for research and development.
  • Interdisciplinary Approaches: The use of interdisciplinary approaches that combine expertise from fields such as biology, chemistry, engineering, data science, and food science.

Foods is committed to providing a platform that enables researchers, industry practitioners, and policymakers to share their findings, discuss challenges, and explore collaborative opportunities in the field of biosensors for the food industry. We look forward to receiving your groundbreaking work and to presenting the innovative research that will be featured in this Special Issue.

Dr. Long Wu
Dr. Sihang Zhang
Dr. Hongji Li
Guest Editors

Dr. Rui Chen
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Foods is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biosensors
  • food safety
  • mycotoxin detection
  • pesticide residue analysis
  • pathogen detection
  • food allergen screening
  • nutrient analysis
  • food authentication
  • environmental monitoring
  • quality control
  • portable biosensors
  • on-site testing
  • nanotechnology
  • microfluidics
  • digital integration
  • data analytics
  • foodborne illness prevention
  • aptasensors
  • electrochemical biosensors
  • optical biosensors
  • immunosensors

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (3 papers)

Order results
Result details
Select all
Export citation of selected articles as:

Research

Jump to: Review

13 pages, 1697 KiB  
Article
Study of Lysozyme Activity in Bird Egg Whites by Fluorescence Polarization Assay Using Chitooligosaccharide Tracer
by Liliya I. Mukhametova, Dmitry O. Zherdev, Anton N. Kuznetsov, Olga N. Yudina, Sergei A. Eremin, Vadim B. Krylov and Nikolay E. Nifantiev
Foods 2025, 14(8), 1365; https://doi.org/10.3390/foods14081365 - 15 Apr 2025
Viewed by 178
Abstract
The storage duration and hatchability of eggs largely depend on the lysozyme content in egg whites; therefore, determining the lysozyme status is important for characterizing their quality. For the first time, a fast and accurate method for determining the active lysozyme in egg [...] Read more.
The storage duration and hatchability of eggs largely depend on the lysozyme content in egg whites; therefore, determining the lysozyme status is important for characterizing their quality. For the first time, a fast and accurate method for determining the active lysozyme in egg whites has been proposed to establish the lysozyme status of eggs using the fluorescence polarization assay and synthetic chitooligosaccharide conjugates with a fluorescent label without sample preparation. The egg whites of hens, black hens, chukars, quails, ducks, geese, turkeys, peacocks, and ostriches were studied. Samples of egg whites from hens, black hens, chukars, and quails demonstrate the possibility of measuring the lysozyme activity. Samples of hen and black hen eggs from a farm showed approximately the same enzymatic activity of lysozyme. A relatively higher enzymatic activity was demonstrated by the samples from quail egg whites; however, a wide range of data was observed among the eggs. Chitooligosaccharide conjugates demonstrate that they bind only to C-type lysozyme, and no interaction with G-type lysozyme has been shown. Lysozyme activity in the egg whites of duck, goose, turkey, peacock, and ostrich eggs has not been detected by using the obtained chitooligosaccharide tracers, which may be related to the structural features of lysozyme in different bird species. Thus, the method of fluorescence polarization (FP), using fluorescently labeled chitopentaoside to determine the lysozyme status, can be used to characterize hen, black hen, chukar, and quail eggs, which will allow for the selection of a batch of eggs with a high content of active lysozyme, for example, for long-term storage. Full article
(This article belongs to the Special Issue Development and Application of Biosensors in the Food Field)
Show Figures

Figure 1

12 pages, 2828 KiB  
Article
An Aptamer Sensor Based on Alendronic Acid-Modified Upconversion Nanoparticles Combined with Magnetic Separation for Rapid and Sensitive Detection of Thiamethoxam
by Qian Huang, Lu Han, Hui Ma, Weijie Lan, Kang Tu, Jing Peng, Jing Su and Leiqing Pan
Foods 2025, 14(2), 182; https://doi.org/10.3390/foods14020182 - 9 Jan 2025
Viewed by 829
Abstract
The widespread use of thiamethoxam has led to pesticide residues that have sparked global concerns regarding ecological and human health risks. A pressing requirement exists for a detection method that is both swift and sensitive. Herein, we introduced an innovative fluorescence biosensor constructed [...] Read more.
The widespread use of thiamethoxam has led to pesticide residues that have sparked global concerns regarding ecological and human health risks. A pressing requirement exists for a detection method that is both swift and sensitive. Herein, we introduced an innovative fluorescence biosensor constructed from alendronic acid (ADA)-modified upconversion nanoparticles (UCNPs) linked with magnetic nanoparticles (MNPs) via aptamer recognition for the detection of thiamethoxam. Through base pairing, thiamethoxam-specific aptamer-functionalized MNPs (apt-MNPs) were integrated with complementary DNA-functionalized UCNPs (cDNA-UCNPs) to create the MNPs@UCNPs fluorescence biosensor. Thiamethoxam specifically attached to apt-MNPs, leading to their separation from cDNA-UCNPs, which in turn led to a reduction in fluorescence intensity at 544 nm following separation by an external magnetic field. The change in fluorescence intensity (ΔI) was directly correlated with the concentration of thiamethoxam, enabling the quantitative analysis of the pesticide. With optimized detection parameters, the biosensor was capable of quantifying thiamethoxam within a concentration span of 0.4–102.4 ng·mL−1, and it achieved a detection limit as minute as 0.08 ng·mL−1. Moreover, leveraging the swift magnetic concentration properties of MNPs, the assay duration could be abbreviated to 25 min. The research exhibited a swift and precise sensing platform that yielded promising results in samples of cucumber, cabbage, and apple. Full article
(This article belongs to the Special Issue Development and Application of Biosensors in the Food Field)
Show Figures

Figure 1

Review

Jump to: Research

27 pages, 6601 KiB  
Review
Advances in Detection Technologies for Pesticide Residues and Heavy Metals in Rice: A Comprehensive Review of Spectroscopy, Chromatography, and Biosensors
by Yu Han, Ye Tian, Qingqing Li, Tianle Yao, Jie Yao, Zhengmao Zhang and Long Wu
Foods 2025, 14(6), 1070; https://doi.org/10.3390/foods14061070 - 20 Mar 2025
Viewed by 594
Abstract
Pesticide residues and heavy metals, originating from diverse sources such as agricultural practices and industrial activities, pose substantial risks to human health and the ecological environment. For instance, residues of organophosphorus pesticides may damage the human nervous system, while heavy metals such as [...] Read more.
Pesticide residues and heavy metals, originating from diverse sources such as agricultural practices and industrial activities, pose substantial risks to human health and the ecological environment. For instance, residues of organophosphorus pesticides may damage the human nervous system, while heavy metals such as mercury and cadmium accumulate in living organisms, potentially leading to severe organ damage. The contamination of rice with these pollutants has become a critical concern, necessitating the development of innovative detection techniques that are sensitive, accurate, rapid, portable, and intelligent. This review offers an in-depth analysis of the types, sources, health risks, and ecological impacts of pesticide residues and heavy metals in rice, providing a comprehensive understanding of the challenges and solutions associated with these contaminants. It further provides the fundamental principles, comparative advantages, and technical constraints of both conventional and emerging detection methodologies. These encompass traditional analytical techniques such as spectroscopy and chromatography, well-established immunoassay systems, as well as innovative biosensing technologies. This discussion is substantiated with representative case studies demonstrating their practical applications in rice quality assessment and safety testing. In addition, this review envisions future directions for the development of detection technologies, emphasizing the importance of miniaturization, multiplexed detection, integration with nanotechnology, and real-time monitoring systems. By providing a theoretical foundation for advancing food safety innovation, this review aims to contribute to the ongoing efforts to ensure rice quality and safety, protect public health, and preserve ecological balance. Full article
(This article belongs to the Special Issue Development and Application of Biosensors in the Food Field)
Show Figures

Figure 1

Back to TopTop