Pollution Effects on Aquatic Life

A special issue of Fishes (ISSN 2410-3888).

Deadline for manuscript submissions: closed (30 December 2018) | Viewed by 5385

Special Issue Editor


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Guest Editor
Department of Zoology, University of Johannesburg, Auckland Park, South Africa
Interests: aquatic toxicology, biomarkers of pollution, aquatic animal health, endocrine disrupting chemicals, reproduction

Special Issue Information

Dear Colleagues,

This Special Issue will focus on the adverse effects of environmental toxicants that are continuously being released into the aquatic environment and the response of aquatic animals.

This Special Issue is associated with contributions in histomorphological effects, immunological, biochemical and physiological mechanisms of toxicity. Additionally, contributions considering the responses of aquatic animals at species, tissue, cellular and molecular level which may serve to identify biological markers that can be used to study the effects of the toxic exposure will also be considered.

Prof. Dr. Ina Wagenaar
Guest Editor

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Keywords

  • aquatic animal health 
  • aquatic toxicology 
  • bioaccumulation 
  • biomarkers of pollution 
  • chronic effects 
  • crude oil 
  • ecotoxicology 
  • endocrine disrupting chemicals 
  • exposure risk and impacts 
  • fish health 
  • haematology effects 
  • heavy metals 
  • histology 
  • histopathology 
  • organochlorine pesticides 
  • pharmaceuticals 
  • polychlorinated biphenyls 
  • reproduction

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Published Papers (1 paper)

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Research

15 pages, 2177 KiB  
Article
Anti-Osteogenic Activity of Cadmium in Zebrafish
by Marco Tarasco, João Cardeira, Michael N. Viegas, Joana Caria, Gil Martins, Paulo J. Gavaia, M. Leonor Cancela and Vincent Laizé
Fishes 2019, 4(1), 11; https://doi.org/10.3390/fishes4010011 - 15 Feb 2019
Cited by 18 | Viewed by 5023
Abstract
Among the many anthropogenic chemicals that end up in the aquatic ecosystem, heavy metals, in particular cadmium, are hazardous compounds that have been shown to affect developmental, reproductive, hepatic, hematological, and immunological functions in teleost fish. There is also evidence that cadmium disturbs [...] Read more.
Among the many anthropogenic chemicals that end up in the aquatic ecosystem, heavy metals, in particular cadmium, are hazardous compounds that have been shown to affect developmental, reproductive, hepatic, hematological, and immunological functions in teleost fish. There is also evidence that cadmium disturbs bone formation and skeletal development, but data is scarce. In this work, zebrafish was used to further characterize the anti-osteogenic/osteotoxic effects of cadmium and gain insights into underlying mechanisms. Upon exposure to cadmium, a reduction of the opercular bone growth was observed in 6-days post-fertilization (dpf) larvae and an increase in the incidence of skeletal deformities was evidenced in 20-dpf post-larvae. The extent and stiffness of newly formed bone was also affected in adult zebrafish exposed to cadmium while regenerating their caudal fin. A pathway reporter assay revealed a possible role of the MTF-1 and cAMP/PKA signaling pathways in mechanisms of cadmium osteotoxicity, while the expression of genes involved in osteoblast differentiation and matrix production was strongly reduced in cadmium-exposed post-larvae. This work not only confirmed cadmium anti-osteogenic activity and identified targeted pathways and genes, but it also suggested that cadmium may affect biomechanical properties of bone. Full article
(This article belongs to the Special Issue Pollution Effects on Aquatic Life)
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