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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Computational Approaches for Medical Diagnosis and Healthcare Settings

edited by

Chenkun Liaw

submission deadline 30 Jan 2027 | Viewed by 152 | Submission Open

Keywords: computer-aided diagnosis; computer-aided healthcare system; overly large healthcare computer system; innovation in health care algorithm

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Deep Learning in Biomedical Image and Signal Processing: Recent Advancements and Applications

edited by Narinder Singh Punn

submission deadline 31 Jan 2027 | 9 articles | Viewed by 13640 | Submission Open

Keywords: deep learning; biomedical image; signal processing; multimodal data fusion; explainable AI

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

AI-Driven Precision Medicine: Innovations in Diagnosis, Prognosis, and Management Response

edited by

Feng Gao

submission deadline 31 Jan 2027 | 5 articles | Viewed by 5776 | Submission Open

Keywords: precision medicine; artificial intelligence; clinical decision support; deep learning; large language models (LLMs); prognosis prediction; medical imaging

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Current Concepts in Fetal and Placental Pathology

edited by

Ovidiu Simion Cotoi

and

Diana-Maria Chiorean

submission deadline 31 Jan 2027 | 2 articles | Viewed by 5199 | Submission Open

Keywords: fetal pathology; placental pathology; perinatal outcomes; perinatal autopsy; maternal-fetal interface; intrauterine growth restriction; preeclampsia; stillbirth; villitis; chorioamnionitis; histopathology; molecular pathology; case reports

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Collaborative Robotics and Total Laboratory Automation in Clinical Diagnostics

edited by

Robert S. Ohgami

submission deadline 31 Jan 2027 | 2 articles | Viewed by 4273 | Submission Open

Keywords: collaborative robotics; total laboratory automation (TLA); diagnostic medicine; clinical validation ; robotic liquid handling ; digital pathology ; clinical microbiology

(This special issue belongs to the Section Clinical Laboratory Medicine)

New Insights into the Diagnosis of Pediatric Cholestasis

edited by Paola Francalanci

submission deadline 31 Jan 2027 | 3 articles | Viewed by 4265 | Submission Open

Keywords: extrahepatic cholestasis; intrahepatic cholestasis; biliary atresia; genetic liver disease; inborn errors of metabolism; jaundice; monogenic liver disease

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advancements in Diagnosis of Colorectal Cancer

edited by

Piero Boraschi

submission deadline 31 Jan 2027 | 3 articles | Viewed by 3730 | Submission Open

Keywords: colorectal cancer; metastatic disease; colorectal liver metastases; chemotherapy; surgery; therapeutic response assessment; biomarkers; tumor regression grading; computed tomography; MRI; PET; intraoperative ultrasound; multidisciplinary management

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Beyond the Tipping Point: Advances in the Diagnosis and Management of Acute-on-Chronic Liver Failure and End-Stage Liver Disease

edited by Jonathan Soldera

submission deadline 31 Jan 2027 | 2 articles | Viewed by 2488 | Submission Open

Keywords: liver cirrhosis; hepatorenal syndrome; acute-on-chronic liver failure; liver transplan-tation; biomarkers; diagnostic imaging; artificial intelligence; inflammation media-tors; prognosis; end-stage liver disease

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Applications of Machine Learning in Obstetrics and Gynecology

edited by Valentina Emilia Balas

submission deadline 31 Jan 2027 | 1 articles | Viewed by 1962 | Submission Open

Keywords: machine learning; obstetrics and gynecology; pregnancy; pregnancy-related complications; reproductive medicine

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Disease Prediction—2nd Edition

edited by

Chi-Chang Chang

and Chalong Cheewakriangkrai

submission deadline 31 Jan 2027 | 3 articles | Viewed by 1314 | Submission Open

Keywords: early diagnostics; medical big data analytics; intelligent diagnostic models in public health; survival analysis and health hazard evaluations; machine learning and generative intelligence; intelligent digital twins; automated/intelligent laboratory recommendation systems

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Diagnosis and Management of Liver Tumors

edited by

Marija Radmilović-Radjenović

submission deadline 31 Jan 2027 | 2 articles | Viewed by 1138 | Submission Open

Keywords: liver tumors; hepatocellular carcinoma; immunotherapy; imaging; oncology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Brain Radiation Necrosis: Emerging Insights in Pathophysiology, Diagnosis, and Management

edited by

Nam P. Nguyen

and Gokoulakrichenane Loganadane

submission deadline 31 Jan 2027 | 1 articles | Viewed by 1039 | Submission Open

Keywords: brain radiation necrosis; radiation therapy; multimodal imaging; differential diagnosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Lung Cancer Diagnosis and Prognosis Prediction

edited by

Jieke Liu

and

Zhigang Chu

submission deadline 31 Jan 2027 | 1 articles | Viewed by 774 | Submission Open

Keywords: lung cancer; CT; artificial intelligence; deep learning; radiomics; habitat imaging; early detection; precision diagnosis; risk stratification; treatment response; prognosis

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Management of Contemporary Issues in Maternal-Fetal Medicine, 2nd Edition

edited by

Ioannis Tsakiridis

submission deadline 31 Jan 2027 | 1 articles | Viewed by 763 | Submission Open

Keywords: maternal-fetal medicine; high-risk pregnancy; pregnancy outcome; pregnancy complications

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Sudden Unexpected Death in Infancy: Advances in Diagnostics and Multidisciplinary Investigation

edited by Maria P. Bonasoni

submission deadline 31 Jan 2027 | 1 articles | Viewed by 693 | Submission Open

Keywords: sudden unexpected death in infancy (SUDI); sudden infant death syndrome (SIDS); post‑mortem diagnostics; multidisciplinary investigation; medicolegal assessment

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Ultrasound and Multimodal Diagnostics in Personalized Medicine

edited by

Ştefan Cristian Vesa

submission deadline 31 Jan 2027 | 2 articles | Viewed by 638 | Submission Open

Keywords: ultrasound; imaging; diagnostics; elastography; contrast-enhanced ultrasound; multimodal imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Molecular Mechanisms in Ophthalmology

edited by Deepshikha Tewari

submission deadline 31 Jan 2027 | Viewed by 491 | Submission Open

Keywords: ophthalmology; molecular mechanisms; cellular processes; pathophysiology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Innovations in Tuberculosis Diagnostics

edited by

Kanagavel Murugesan

submission deadline 31 Jan 2027 | Viewed by 366 | Submission Open

Keywords: whole genome sequencing (WGS); targeted NGS; computer-aided detection (CAD); digital radiography; exosomes; volatile organic compounds; loop-mediated isothermal amplification (LAMP); NAAT; transcriptomics; proteomics; lateral flow assays

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Precision Diagnostics in Lung and Respiratory Diseases

edited by

Evgeni Gershman

submission deadline 31 Jan 2027 | Viewed by 328 | Submission Open

Keywords: obstructive airway disease; interstitial lung disease; molecular diagnosis; thoracic imaging; biopsy of lung lesion

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Breakthroughs in Advanced Medical X-Ray and CT Imaging: From Technology to Clinical Application

edited by Joyoni Dey

submission deadline 31 Jan 2027 | Viewed by 321 | Submission Open

Keywords: advanced X-ray CT imaging; X-ray CT interferometry; phase-contrast X-ray; photon-counting detectors

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advanced Meta-Analytical Approaches and Novel Diagnostic Technologies in Cardiovascular Medicine

edited by

Raheel Ahmed

submission deadline 31 Jan 2027 | Viewed by 288 | Submission Open

Keywords: meta-analysis; evidence synthesis; cardiovascular diagnosis; clinical evidence; evidence-based medicine; diagnostic accuracy; systematic review

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Updated in Endocrine Pathology: From New Diagnosis Tools to Cross-Disciplinary Teams

edited by

Mara Carsote

submission deadline 31 Jan 2027 | Viewed by 223 | Submission Open

Keywords: adrenal; adrenalectomy; thyroid; thyroid cancer; thyroidectomy; pituitary gland; prolactin; hormone; endocrine; dynamic testing; biomarker; computer tomography; magnetic resonance imaging; scintigraphy; DXA; osteoporosis; bone; muscle

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Cardiovascular Diseases: Diagnosis and Management, Second Edition

edited by Hezzy Shmueli

submission deadline 31 Jan 2027 | Viewed by 222 | Submission Open

Keywords: real-time imaging; cardiovascular disease; cardiovascular imaging; echocardiography; cardiac CT; cardiac MRI; cardiac nuclear scan; acute cardiac care; artificial intelligence; cardiomyopathy

(This special issue belongs to the Section Medical Imaging and Theranostics)

Kidney Disease: Biomarkers, Diagnosis, and Prognosis—4th Edition

edited by

Akito Maeshima

submission deadline 31 Jan 2027 | Viewed by 167 | Submission Open

Keywords: primary/secondary glomerulonephritis; rapidly progressive glomerulonephritis; nephrotic syndrome; acute kidney injury; chronic kidney disease; diabetic nephropathy/diabetic kidney disease; chronic renal failure; kidney transplantation; renal fibrosis; polycystic kidney

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Machine Learning for Computer-Aided Diagnosis in Biomedical Imaging—3rd Edition

edited by

Farhan Akram

submission deadline 31 Jan 2027 | Viewed by 162 | Submission Open

Keywords: cancer diagnosis; medical images; electronic health records; machine learning; deep learning; artificial intelligence; explainable AI models; multi-modal analysis; federated learning; CAD systems

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Oral and Maxillofacial Tumors and Salivary Gland Diseases

edited by

Maria Cristofaro

submission deadline 31 Jan 2027 | Viewed by 155 | Submission Open

Keywords: salivary gland tumors; oral squamous cell carcinoma; maxillofacial surgery; intraoperative nerve monitoring; prognostic biomarkers

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

AI and Explainable Intelligence for Medical Diagnosis: Emerging Trends and Future Directions

edited by

Olamilekan Shobayo

submission deadline 31 Jan 2027 | Viewed by 155 | Submission Open

Keywords: artificial intelligence; deep learning; vision transformers (ViTs); generative AI (GANs; VAEs; diffusion models); multimodal learning; radiology AI; image segmentation and classification; explainable AI (XAI); clinical decision support; medical image analysis

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Biomarkers and Biodiagnostics in Neurodegenerative Diseases

edited by

Ludmilla Morozova-Roche

submission deadline 31 Jan 2027 | Viewed by 111 | Submission Open

Keywords: neurodegenerative diseases; biomarkers; biodiagnostics; protein misfolding

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Imaging‑Guided Oral and Maxillofacial Diagnosis

edited by Aleksa Janović

submission deadline 31 Jan 2027 | Viewed by 39 | Submission Open

Keywords: cone-beam computed tomography; dental MRI; ultrasound; computed tomography; image-based 3D modeling; artificial intelligence; digital image analysis

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Laboratory Diagnosis: Biomarker Validation and Diagnostic Performance

edited by

Ivana Lapić

submission deadline 31 Jan 2027 | Viewed by 29 | Submission Open

Keywords: biomarkers; validation; diagnostic accuracy; clinical performance; patient safety

(This special issue belongs to the Section Clinical Laboratory Medicine)

Diagnosis and Management of Adverse Drug Reactions in Precision Medicine and Big Data

edited by

Elena Ramírez

submission deadline 28 Feb 2027 | 1 articles | Viewed by 17559 | Submission Open

Keywords: adverse drug reactions; pharmacovigilance; drug safety; risk factors; causality assessment; big data; precision medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Ultrasound Diagnosis and Guided Intervention of Musculoskeletal/Neuromuscular Pathology, Second Edition

edited by

Ke-Vin Chang

submission deadline 28 Feb 2027 | 6 articles | Viewed by 16340 | Submission Open

Keywords: diagnosis; ultrasound; pain; muscle; tendon; nerve; rehabiltation

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advanced Role of Endoscopic Ultrasound in Clinical Medicine

edited by

Germana De Nucci

submission deadline 28 Feb 2027 | 3 articles | Viewed by 7407 | Submission Open

Keywords: endoscopic ultrasound (EUS); diagnostic imaging; fine needle aspiration (FNA); contrast-enhanced EUS; elastography techniques

(This special issue belongs to the Section Medical Imaging and Theranostics)

Artificial Intelligence in Diagnosis and Management of Cardiovascular Diseases

edited by

Corina Maria Vasile

and Xavier Iriart

submission deadline 28 Feb 2027 | 4 articles | Viewed by 7116 | Submission Open

Keywords: cardiovascular diseases; artificial intelligence; deep learning; machine learning; wearable devices; imaging techniques; personalized medicine; risk prediction; telemedicine; remote monitoring; ethical considerations

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Application of Ultrasound Imaging in Clinical Diagnosis

edited by

Jinbum Kang

submission deadline 28 Feb 2027 | 6 articles | Viewed by 5995 | Submission Open

Keywords: diagnostic ultrasound imaging and systems; doppler ultrasound techniques and applications; elastography for tissue characterization; contrast-enhanced ultrasound (CEUS); artificial intelligence in diagnostic ultrasound; point-of-care ultrasound (POCUS); ultrasound-guided interventions

(This special issue belongs to the Section Medical Imaging and Theranostics)

Clinical Anatomy and Diagnosis of Peripheral Nervous System—2nd Edition

edited by

Alexandra Diana Vrapciu

submission deadline 28 Feb 2027 | 2 articles | Viewed by 5404 | Submission Open

Keywords: anatomy; peripheral nervous system; imaging

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Endoscopy in Gynecology and Gynecologic Oncology

edited by

Rudolf Lampé

submission deadline 28 Feb 2027 | 1 articles | Viewed by 4276 | Submission Open

Keywords: gynecology; endoscopy; operative gynecology

(This special issue belongs to the Section Medical Imaging and Theranostics)

Precise Diagnosis, Classification, and Monitoring of Pulmonary Diseases

edited by

Barbara Ruaro

Paola Confalonieri

and

Francesco Salton

submission deadline 28 Feb 2027 | 2 articles | Viewed by 3071 | Submission Open

Keywords: lung diseases; pulmonary diseases; imaging techniques; causal biological pathways; clinical biomarkers

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Artificial Intelligence in Biomedical Signal and Imaging Processing

edited by

Ankush D. Jamthikar

submission deadline 28 Feb 2027 | 2 articles | Viewed by 2127 | Submission Open

Keywords: artificial intelligence; biomedical imaging; signal processing; unsupervised learning; generative artificial intelligence; image reconstruction; image segmentation; data augmentation; physiological signal analysis; personalized medicine; artificial intelligence-driven diagnostics; self-supervised learning

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Inflammation and Infection Imaging: 2nd Edition

edited by

Giorgio Treglia

submission deadline 28 Feb 2027 | 2 articles | Viewed by 1837 | Submission Open

Keywords: imaging; infection; inflammation; radiology; nuclear medicine; molecular imaging; hybrid imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Advances in Clinical Biochemical Testing: 2nd Edition

edited by

Tar-Choon Aw

submission deadline 28 Feb 2027 | Viewed by 781 | Submission Open

Keywords: clinical chemistry; diagnostic testing; biomarkers; point-of-care testing; mass spectrometry; immunoassays; microfluidics

(This special issue belongs to the Section Clinical Laboratory Medicine)

Imaging of Long-COVID (Post-Acute Sequelae of COVID, PASC) and Post-Infectious Syndromes

edited by

Eric Guedj

submission deadline 28 Feb 2027 | 1 articles | Viewed by 730 | Submission Open

Keywords: long COVID; post-acute sequelae of COVID (PASC); COVID-19; SARS-CoV-2; post-infectious syndromes; myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS); medical imaging; nuclear medicine; PET; SPECT; MRI; CT; ultrasound; imaging biomarkers; metabolism; neuroinflammation; microvascular dysfunction; multisystem involvement; diagnosis; prognosis; rehabilitation; functional impairment

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in the Diagnosis of Skin Disease: 2nd Edition

edited by

Gerardo Cazzato

submission deadline 28 Feb 2027 | 1 articles | Viewed by 699 | Submission Open

Keywords: dermatology; dermatopathology; skin diseases; neoplastic diseases; inflammatory dermatopathology; CTCL; melanoma; squamous cell carcinoma; basal cell carcinoma; infectious diseases

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Quantitative Imaging of Respiratory Diseases: Techniques and Clinical Applications

edited by Chenwang Jin and

Yanrong Chen

submission deadline 28 Feb 2027 | Viewed by 637 | Submission Open

Keywords: quantitative imaging; HRCT; radiomics; machine learning; respiratory diseases; imaging biomarkers

(This special issue belongs to the Section Medical Imaging and Theranostics)

Multimodal Assessment of Musculoskeletal Conditions

edited by

Stanley K. H. Lam

and Bradley Dean Fullerton

submission deadline 28 Feb 2027 | Viewed by 606 | Submission Open

Keywords: musculoskeletal disorders; multimodal assessment; biotensegrity; diagnostic ultrasound; imaging; biomechanics; rehabilitation monitoring; patient-reported outcomes

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advanced Imaging and Artificial Intelligence in Emergency Body Radiology

edited by

Francesco Verde

and

Francesca Iacobellis

submission deadline 28 Feb 2027 | Viewed by 587 | Submission Open

Keywords: emergency radiology; advanced imaging; artificial intelligence; dual-energy CT; photon-counting CT; MRI acceleration; contrast-enhanced ultrasound; deep learning; radiomics; workflow optimisation; clinical validation

(This special issue belongs to the Section Medical Imaging and Theranostics)

Innovative Biomarkers and Diagnostic Strategies in Immune-Mediated Diseases

edited by

Marcos López Hoyos

submission deadline 28 Feb 2027 | Viewed by 476 | Submission Open

Keywords: immune-mediated diseases; innovative biomarkers; diagnostic strategies; classification criteria; laboratory techniques

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Clinical Diagnosis and Management in Anesthesia and Pain Medicine: 2nd Edition

edited by Jamal Hasoon

submission deadline 28 Feb 2027 | Viewed by 342 | Submission Open

Keywords: anesthesia and pain medicine; interventional pain management; regional anesthesia; neuromodulation; treatment outcomes; clinical practice patterns; diagnosis; management

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Emerging Diagnostic Technologies in Orthopedics: Advancing Personalized Implant Design and Therapeutics

edited by

Neil Ashwood

submission deadline 28 Feb 2027 | Viewed by 266 | Submission Open

Keywords: patient-specific implant design; advanced diagnostic technologies; computational biomechanics; surgical navigation systems; implant manufacturing; intraoperative monitoring; postoperative evaluation; biomedical engineering; clinical implant optimization; precision medicine

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Diagnosis and Treatment of Digestive System Diseases

edited by

Zhendong Jin

submission deadline 28 Feb 2027 | Viewed by 234 | Submission Open

Keywords: digestive system diseases; endoscopic diagnostic techniques; AI-assisted endoscopy; gastrointestinal malignancy; molecular biomarkers; minimally invasive therapy; precision diagnosis; clinical translational research

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Displaying special issue 551-600 on page 12 of 13.

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