Natural Compounds: An Adjuvant Strategy in Cancer Management
A special issue of Current Issues in Molecular Biology (ISSN 1467-3045). This special issue belongs to the section "Bioorganic Chemistry and Medicinal Chemistry".
Deadline for manuscript submissions: 30 June 2025 | Viewed by 1616
Special Issue Editors
Interests: dysregulated metabolic pathways; cancer; inflammation; epigenetic modifications
Special Issues, Collections and Topics in MDPI journals
Interests: oxidative and nitrosative stress; bioactive compunds; NCDs; ageing; taste recognition
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
According to the World Health Organization (WHO)’s latest estimates, in 2022, there were 20 million new cancer diagnoses and 9.7 million cancer deaths globally. The therapeutic strategy against cancer depends on several factors, including the type and stage of cancer, a patient’s general health status and their tolerance to chemotherapy treatment (if needed). In fact, adverse drug reactions often force doctor’s to reduce the dose of treatment. As a consequence, patients risk being undertreated, resulting in worsen oncologic outcomes. Phytochemicals (as well phenolics, flavonoids, and carotenoids) are dietary bioactive compounds present in fruits and vegetables known to act, under certain conditions, as pro-oxidant and cytotoxic agents in certain tissues, including tumour cells. Due to their properties, dietary phytochemicals are used to supplement conventional chemotherapy drugs to increase anti-tumor efficacy, or they can be modified to synthesize novel anti-cancer formulations less cytotoxic to normal tissue cells and more effective against cancer. In this Special Issue, we invite authors to submit original research and review articles investigating different metabolic changes in cancer cells due to the administration of natural compounds and their derivatives. Also, we gratefully appreciate all contributions focused on the identification of new therapeutic approaches using vegetable bioactive compounds in patients for improving positive outcomes in cancer treatment.
Dr. Monia Cecati
Dr. Arianna Vignini
Guest Editors
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Keywords
- cancer
- phytochemicals
- bioactive compounds
- anti-tumor
- cancer treatment
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