Acute Myeloid Leukemia in Pediatrics

Dear Colleagues,

Given the still limited prognosis for children suffering from AML, I would like to propose a comprehensive Special Issue in Children entitled “Acute Myeloid Leukemia in Pediatrics”.
Although some cooperative childhood AML study groups have achieved survival rates of more than 70%, the prognosis in most parts of the world is still terribly low.
Therefore, continuous efforts in research, diagnostics and therapy are necessary to improve the outcome and cure rates in pediatric AML.
Merging the most recent results from basic and translational research with innovative treatment approaches, this Special Issue will give an excellent overview and may provide standards within a broad community.
The most recent developments in global cooperative projects highlight the urgent need to update and align the knowledge on all levels of research, diagnostics and therapy in pediatric AML.
This Special Issue should cover the latest results and standards regarding leukemic stem cell hierarchy and evolution, diagnostics, prognostic factors and successful treatment approaches in childhood AML. The encouraging results of cellular and immune therapies should be discussed. In addition, the current treatment options in relevant subgroups such as treatment-related AML or AML associated with predisposition syndromes should be included.
I believe that this will provide not only a valuable update on this topic but also a unique guideline for pediatricians worldwide.

Prof. Dr. Dirk Reinhardt
Guest Editor

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