Pediatric Asthma: Advances in Diagnosis, Novel Therapies, and Long-Term Outcomes

A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Pediatric Pulmonary and Sleep Medicine".

Deadline for manuscript submissions: 25 December 2025 | Viewed by 55

Special Issue Editor


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Guest Editor
National Centre for Respiratory Pharmacoeconomics and Pharmacoepidemiology, 37124 Verona, Italy
Interests: asthma; cough; inhalation devices and their usability; pharmacoeconomics of respiratory diseases
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Special Issue Information

Dear Colleagues,

I warmly invite you to contribute your expertise and research to the Children Special Issue on Pediatric Asthma: Advances in Diagnosis, Novel Therapies, and Long-Term Outcomes.

Background and history of this topic: Bronchial asthma is the most common chronic respiratory disorder affecting both children and adolescents. Despite advances in care, its morbidity and mortality still remains significant, with some regional differences. A natural history of asthma is difficult to predict in individuals. In general, life expectancy is positive in the absence of severe comorbidities, and fatalities are infrequent when asthma is properly managed. From its onset, asthma is an inflammatory disease of the airways that affects all components of the bronchial wall, such as the epithelium, the muscle, and the vasculature, to varying degrees. Unfortunately, asthma is often diagnosed only after several years of symptoms in young people, as it is usually only recognized after the first severe respiratory crisis. When accurate and timely diagnosis is missing, appropriate therapeutic strategies are delayed, and progressive structural damage to the airways becomes difficult to prevent.

The clinical presentation of asthma can frequently change from childhood to adolescence, with many patients experiencing a spontaneous decline of respiratory symptoms that can lead to mistaken conclusions that asthma has been cured, resulting in the premature discontinuation of preventive treatments. The psychological profile of adolescents and their relationship with their families are also crucial factors.  any adolescents perceive asthma as an episodic condition that exists only during exacerbations and may resist regular treatment during asymptomatic periods. Their adherence to regular treatment is partially influenced by the complexity of the therapeutic regimen and the types of inhalation devices prescribed. However, with proper education and support, asthmatic adolescents tend to develop a self-focused cognitive style and a high sense of personal responsibility for themselves and their future. The upcoming Special Issue will aim to highlight novel aspects of pediatric asthma, including pathogenesis, early diagnosis, triggers, timely treatment, inhalation systems and devices, and the importance of educational and psychological support.

Aim and scope of the Special Issue: Asthma is a multifaceted condition that is difficult to recognize and manage, particularly in young people, as several factors (genetic, environmental, occupational, hormonal and psychological) can influence its evolution over time. For these reasons, a new Special Issue has been dedicated to innovations in pediatric asthma, with the aim of updating and optimizing each step of the diagnostic pathway and therapeutic approach, thus avoiding preventing asthma from evolving into a disabling condition.

Cutting-edge research: Whichever report on innovation research concerning pediatric asthma

What kind of papers we are soliciting: Papers concerning updating knowledge in biological factors and mediators involved in pediatric asthma; Papers concerning innovation in the clinical aspect, diagnostic approach, and management of pediatric asthma, AI included.

Dr. Roberto W. Dal Negro
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • pediatric asthma
  • advances in diagnosis
  • novel therapies
  • long-term outcomes
  • AI in asthma

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Published Papers

This special issue is now open for submission.
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