Late-Preterm and Early-Term Newborns: Risk Factors, Outcomes and New Challenges

A special issue of Children (ISSN 2227-9067).

Deadline for manuscript submissions: 10 January 2026 | Viewed by 328

Special Issue Editor


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Guest Editor
II Department of Neonatology, Poznan University of Medical Sciences, Poznan, Poland
Interests: newborns' infectious diseases; congenital and acqyired CMV infection; postnatal growth faltering; newborns of diabetic mothers; late-preterm and early-term infants
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Special Issue Information

Dear Colleagues,

Late-preterm (born between 340/7 and 366/7 weeks of gestation) and early-term (370/7-386/7) infants are the fastest-growing subgroups of neonates. In Western countries, late-preterm and early-term birth rates range from 3% to 6% and from 15% to 30%, respectively, and over the past decade, they have increased by around 10%.

Late-preterm infants generally appear to be relatively mature and healthy; however, emerging evidence identifies them as being at a significant risk of several neonatal morbidities. Recent research shows that early-term newborns, who usually look like full-term infants, are more likely to experience adverse neonatal outcomes than those born after 39 weeks.

As the Guest Editor of this Special Issue, ‘Late-Preterm and Early-Term Newborns: Risk Factors, Outcomes and New Challenges’, I cordially invite you to submit reviews, research articles, or case reports, which will undoubtedly broaden our knowledge on health challenges posed by late-preterm and early-term infants.

Dr. Katarzyna Wroblewska-Seniuk
Guest Editor

Manuscript Submission Information

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Keywords

  • late-preterm newborns
  • early-term newborns
  • neonatal morbidity
  • prematurity risk factors
  • respiratory disease
  • neurodevelopmental outcomes
  • neonatal infections

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Published Papers (1 paper)

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Review

23 pages, 1023 KiB  
Review
Short- and Long-Term Consequences of Late-Preterm and Early-Term Birth
by Muhammad Arham and Katarzyna Wróblewska-Seniuk
Children 2025, 12(7), 907; https://doi.org/10.3390/children12070907 - 9 Jul 2025
Viewed by 60
Abstract
Late-preterm (340/7–366/7 weeks) and early-term (370/7–386/7 weeks) newborns were, up until recently, erroneously categorized as low-risk and were conflated with full-term (390/7–406/7 weeks) deliveries. However, emerging evidence refuted this notion and demonstrated that late-preterm [...] Read more.
Late-preterm (340/7–366/7 weeks) and early-term (370/7–386/7 weeks) newborns were, up until recently, erroneously categorized as low-risk and were conflated with full-term (390/7–406/7 weeks) deliveries. However, emerging evidence refuted this notion and demonstrated that late-preterm and, to a lesser extent, early-term newborns have a significantly higher risk of experiencing various neonatal morbidities, including respiratory distress syndrome, transient tachypnea of the newborn, pneumonia, jaundice, hypoglycemia, and breastfeeding difficulties, compared to their full-term counterparts—reflecting their relative physiologic and developmental immaturity. Recent evidence also unravels the lingering adverse effects of late-preterm and early-term delivery up until mid-adulthood, with the increased susceptibility of these newborns to neurodevelopmental delays, behavioral and neuropsychiatric problems, and adult chronic diseases. Moreover, apart from increased neonatal and infant mortality rates, these newborns continue to encounter a heightened risk of mortality even up to mid-adulthood. As the full spectrum of the complications these newborns face is gradually being unveiled, this review presents and discusses the current knowledge base, identifies gaps in the literature, and highlights future research implications. Full article
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