Pediatric Neurocritical Care: Diagnosis, Neuromonitoring and Outcomes

A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Pediatric Neurology & Neurodevelopmental Disorders".

Deadline for manuscript submissions: 25 February 2026 | Viewed by 1

Special Issue Editors


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Guest Editor
Section Neurology, Department of Pediatrics, Cumming School of Medicine, Alberta Children’s Hospital, University of Calgary, 28 Oki Drive NW, Calgary, AB T3B 6A8, Canada
Interests: neuro-critical monitoring; EEG; pediatric neurodevelopment

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Guest Editor
1. Hotchkiss Brain Institute (HBI), University of Calgary, Calgary, AB, Canada
2. Alberta Children's Hospital Research Institute (ACHRI), University of Calgary, Calgary, AB, Canada
3. Department of Pediatrics, Section of Neurology, University of Calgary, Calgary, AB, Canada
Interests: pediatric brain injury; neurocritical care; translational biology; determinants of health; health outcomes; knowledge translation; novel therapeutics

Special Issue Information

Dear Colleagues, 

Over the past two decades, pediatric neurocritical care has emerged as a distinct, multidisciplinary field focused on improving survival and neurodevelopment in critically ill children with acute brain injury. Advances in neuroimaging, electrophysiology, and multimodal neuromonitoring have transformed bedside diagnosis and informed targeted interventions, yet major challenges remain in translating physiologic data into outcome-changing therapies.

Currently, cutting-edge research is focused on integrating continuous multimodal data streams—EEG, cerebral oxygenation, intracranial pressure, and advanced neuroimaging—into predictive models for individualized care. Biomarker discovery, automated seizure detection, and AI-driven analytics are expanding our ability to detect injury earlier, guide interventions in real time, and forecast recovery trajectories. Parallel work is refining neuroprotective strategies, optimizing sedation and seizure management, and expanding outcome measures beyond survival to capture functional and quality-of-life endpoints.

This Special Issue seeks original research, clinical trials, translational studies, and high-quality reviews addressing diagnosis, monitoring, and prognostication in pediatric neurocritical care. Topics of interest include novel monitoring technologies, biomarker validation, predictive modeling, neuroprotective interventions, and multidisciplinary care models. Global health perspectives and ethical considerations are also welcome.

By uniting diverse expertise, this Special Issue aims to accelerate innovation and shape future standards that improve the lives of children with acute brain injury.

Dr. Kristine Woodward
Prof. Dr. Michael J. Esser
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • pediatric neurocritical care
  • acute brain injury
  • traumatic brain injury
  • hypoxic–ischemic encephalopathy
  • status epilepticus
  • central nervous system infections
  • stroke in children
  • multimodal neuromonitoring
  • continuous EEG monitoring
  • intracranial pressure monitoring
  • cerebral oxygenation
  • advanced neuroimaging
  • biomarkers
  • neuroprotection
  • prognostic modeling
  • artificial intelligence in critical care
  • seizure detection
  • outcome prediction
  • neurodevelopmental outcomes
  • multidisciplinary critical care

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Published Papers

This special issue is now open for submission.
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