Special Issue "Simple Organisms for Complex Problems: Modeling Human Disease in Yeast and Dictyostelium"
Deadline for manuscript submissions: closed (31 December 2019).
We all know that the use of simple models is fundamental in basic research. The molecular mechanisms that regulate most cellular processes are highly conserved between mammals and simple eukaryotes, which justify the use of these experimental models to more rapidly advance and open up new avenues of research. However, does it make sense for example to use a brainless organism to study neurodegenerative diseases or any other complex human disease? The answer is definitively “yes”, and we have plenty of examples in the scientific literature showing the importance of using these simple models for dissecting complex disease-related pathways. Common and rare neurodegenerative diseases, infection, metabolic and mitochondrial diseases and many others diseases may benefit from the use of these models to gain a better understanding of the molecular bases of disease and find new therapeutic opportunities.
This Special Issue will welcome contributions focused on simple organisms, such as Saccharomyces cerevisiae and Dictyostelium discoideum to unravel the bases of human disease.
Dr. Ricardo Escalante
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Dictyostelium discoideum
- Saccharomyces cerevisiae
- human disease
- model organisms