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Special Issue "Mitochondrial Biology in Health and Disease"
Deadline for manuscript submissions: closed (31 December 2018).
Interests: mitochondrial biology and disease; neurodegenerative disease; AMPK; TOR complex I; cellular stress signalling
Special Issues and Collections in MDPI journals
Best known as the site of respiratory ATP production, the mitochondria have been revealed over the past quarter-century as being deeply embedded in all aspects of the life of the eukaryotic cell. They are the product of two genomes whose expression must be coordinated by information shared in both directions between them and the nucleus. They participate in critical central metabolic pathways and they are fully integrated into the intracellular signalling networks that regulate diverse cellular functions. It is not surprising then that mitochondrial defects or dysregulation have emerged as having key roles in ageing and in the cytopathological mechanisms underlying cancer, neurodegenerative and other diseases.
This Special Issue of Cells is devoted to all aspects of mitochondrial function and dysfunction in healthy and diseased cells. It will contain articles that collectively provide a balanced, state-of-the-art view of mitochondrial biology. We seek submissions of high quality articles on including, but not limited to, mitochondrial biogenesis, metabolism, regulation, gene expression, signalling and roles in ageing and disease. Because of the vital and powerful contributions made by model organisms to understanding human biology and disease, we encourage manuscripts that describe or include the use of simple model systems to explore mitochondrial biology in health and disease.Prof. Paul Robert Fisher
Dr. Sarah Annesley
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- mitochondrial biogenesis
- mitochondrial metabolism
- mitochondrial replication
- mitochondrial gene expression
- mitochondrial cell death
- mitochondrial signalling
- mitochondrial membrane transporters
- mitochondrial respiration
- neurodegenerative disease
- cellular stress responses
- ER-mitochondria interactions
- Parkinson’s disease
- Alzheimer’s disease
- Huntington’s disease