Mitochondrial Biology in Health and Disease

Dear Colleagues,

Best known as the site of respiratory ATP production, the mitochondria have been revealed over the past quarter-century as being deeply embedded in all aspects of the life of the eukaryotic cell. They are the product of two genomes whose expression must be coordinated by information shared in both directions between them and the nucleus. They participate in critical central metabolic pathways and they are fully integrated into the intracellular signalling networks that regulate diverse cellular functions. It is not surprising then that mitochondrial defects or dysregulation have emerged as having key roles in ageing and in the cytopathological mechanisms underlying cancer, neurodegenerative and other diseases.

This Special Issue of Cells is devoted to all aspects of mitochondrial function and dysfunction in healthy and diseased cells. It will contain articles that collectively provide a balanced, state-of-the-art view of mitochondrial biology. We seek submissions of high quality articles on including, but not limited to, mitochondrial biogenesis, metabolism, regulation, gene expression, signalling and roles in ageing and disease. Because of the vital and powerful contributions made by model organisms to understanding human biology and disease, we encourage manuscripts that describe or include the use of simple model systems to explore mitochondrial biology in health and disease.

Prof. Paul Robert Fisher
Dr. Sarah Annesley
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.