Dental Pulp Stem Cells and Regenerative Medicine

Dear Colleagues,

Dental pulp stem cells (DPSCs), a type of mesenchymal stem cells isolated from dental pulp, have higher cell proliferative ability than and mostly comparable differentiation capacity to other types of stem cells, such as bone-marrow-derived mesenchymal stem cells and adipose-tissue-derived mesenchymal stem cells. Moreover, DPSCs are easy to collect without severe impairment in their donor site because they are easily obtained from extracted teeth. Furthermore, it has been suggested in animal studies that DPSCs may be efficacious even for the treatment of spinal cord injury, Alzheimer’s disease, Parkinson’s disease, and so forth. Consequently, DPSCs are considered to be a good, realistic, and prospective candidate for cell sources for various cell-based therapies including regenerative medicine for damaged organs and tissues.

In this Special Issue of Cells, I invite you to contribute, in the form of original research articles, reviews, or shorter perspective articles, on all aspects related to the theme of “Dental Pulp Stem Cells and Regenerative Medicine”. Expert articles describing cellular and/or molecular aspects of proliferation and/or differentiation of DPSCs are highly welcome. Methodological articles describing the propagation and differentiation induction of DPSCs are also welcomed. Relevant topics include, but are not limited to:

• Mesenchymal stem cells;
• Neural crest cells;
• Bone marrow;
• Adipose tissue;
• Cell proliferation;
• Cell differentiation;
• Signal transduction;
• Extracellular matrix;
• Growth factors;
• Cell culture;
• Scaffolds;
• Cell sheets;
• Preservation;
• Transplantation;
• Bone;
• Dentin;
• Cartilage;
• Tooth;
• Tissue engineering;

Prof. Dr. Kazuhito Satomura
Dr. Masaki Honda
Guest Editor

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