Molecular Mechanisms of Chronic Intestinal Diseases in Response to Microbiota
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Immunology".
Deadline for manuscript submissions: closed (15 May 2022) | Viewed by 48435
Special Issue Editor
Interests: gastroenterology; intestine; intestinal microbiota; intestinal inflammation; TLR signaling; serotoninergic system; intestinal motility; colon cancer; metallodrugs; nanomolecules
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Inflammatory bowel diseases (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), are chronic inflammatory disorders of the intestine, involving complex interactions between host and microbiota.
The composition of the microbiota can be influenced by a variety of environmental factors, including diet, antibiotics, stress, etc. An intestinal dysbiosis may induce aberrant interactions between gut epithelium and microbiota and result in inflammatory responses to commensal microbes. Among the action mechanisms implicated in these inflammatory responses are those involved in intestinal barrier function, innate immune recognition of microbial ligands (TLR, NOD receptors), antigen presentation, T-cell immunity, autophagy, reactive oxygen generation, goblet cell/mucin production, antimicrobial peptides, Paneth cells or inflammatory mediator production.
In this Special Issue of Cells, I invite you to contribute original research articles, reviews, or shorter perspective articles on all aspects related to the theme of “Molecular Mechanisms Involved in Chronic Intestinal Diseases in Response to Microbiota”. Expert articles describing mechanistic, functional, cellular, biochemical, or general aspects of intestinal inflammation in response to microbiota are highly welcome. Relevant topics include but are not limited to:
Microbiota;
Immunology in IBD;
Intestinal inflammation;
Cytokine signaling;
Pattern recognition receptors (TLR, NOD, RLR, CLR);
Oxidative stress;
Autophagy;
Antimicrobial peptides;
Mucin production;
Paneth cells;
Prebiotics;
Probiotics;
In vitro and in vivo models.
Dr. Laura Grasa
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue policies can be found here.