Advancements in Research on hiPSC-Derived Cells
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Stem Cells".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 344
Special Issue Editor
Interests: human induced pluripotent stem cells; hematopoietic stem cells; hematopoietic progenitors; hemogenic endothelial cells; endothelial cells; T cells; NK cells; macrophages; B cells
Special Issue Information
Dear Colleagues,
Induced pluripotent stem cells (iPSCs) have transformed regenerative medicine by providing a sustainable source of numerous cell types and enabling researchers to generate patient-specific cells for drug testing and transplantation. These cells have significant applications in neurological disorders, immunotherapy, and precision medicine and can differentiate into neurons, cardiomyocytes, and immune cells (mainly T cells, NK cells, B cells, and macrophages), allowing personalized treatment.
Recent advancements in genetic engineering, particularly the introduction of CRISPR-Cas9, have enhanced iPSC-derived cell applications. By correcting genetic mutations, this gene-editing tool refines disease modeling, drug screening, and cell-based therapies. Cancer and autoimmune disease treatment has improved due to the generation of immune cells such as T and NK cells. These breakthroughs make cell-based immunotherapies more accessible and practical. As genetic engineering and cell differentiation progress, iPSCs have the potential to revolutionize disease treatment and improve human health, particularly in neurological, cardiac, and immune disorders.
We invite researchers and scientists to contribute to this growing field by submitting their original research articles and review papers on hiPSC-derived cells. Topics of interest include but are not limited to the following:
- Advances in iPSC technology and differentiation methods.
- Genetic engineering in iPSCs using the CRISPR-Cas9 system and its applications.
- iPSC-derived cells for cardiac disorders and hematological, neurological, and regenerative medicine.
- Immune cell generation from iPSCs and their role in immunotherapy.
- Translational challenges in iPSC applications.
We encourage you to submit your manuscript for consideration if you are currently conducting related research. We look forward to your contributions to advancing this dynamic field.
Dr. Akhilesh Kumar
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- hiPSCs
- hematopoietic progenitors
- T cells
- NK cells
- cardiac cells
- B cells
- macrophages
- neutrophiles
- CRISPR/Cas9 technology
- genetic engineering
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
