Diagnosis and Treatment of Primary and Secondary Lung Cancers

Dear Colleagues,

Both primary and secondary tumors of the chest are major issues for clinicians; in fact, on the one hand, primary lung cancer is one of the most frequently diagnosed cancers and is the leading cause of cancer-related death worldwide. On the other hand, the lung is the second most common site of metastases, and pulmonary metastasectomy is the most frequent surgical resection undertaken by thoracic surgeons. Significant developments have recently been shown in clinical settings, both in terms of diagnosis and treatment: for example, the early diagnosis of lung nodules by computed tomography screening, circulating miRNA detection, minimally invasive diagnostic and therapeutic approaches such as endobronchial ultrasound, video-assisted thoracic surgery and robot-assisted thoracic surgery, immunotherapy, TKI inhibitors, and stereotactic body radiation therapy (SBRT) represent only some of the most significant and recent goals.

Moreover, other thoracic malignancies such as chest wall tumors, mediastinal tumors, and mesothelioma, although rare, represent the most advanced frontier of modern oncology.

In this Topical Collection, we would like to focus on the most significant cornerstones in the diagnosis and therapy of both primary and secondary thoracic cancers.

It is our pleasure to lead such a comprehensive Topical Collection, and we look forward to receiving your valuable contributions.

Prof. Francesco Petrella
Collection Editor

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