New Insights into Neurofibromatosis
A special issue of Cancers (ISSN 2072-6694).
Deadline for manuscript submissions: closed (31 August 2019) | Viewed by 57645
Special Issue Editors
2. Academic Alliance for Skull Base Pathology, Maastricht and Radboud University Medical Centers, 6229 ER Maastricht, The Netherlands
Interests: chordoma; meningioma; vestibular schwannoma; deep brain stimulation for movement and psychiatric disorders
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The neurofibromatosis family of hereditary tumor predisposition disorders significantly impair quality-of-life and lead to early mortality through the development of innumerable nervous system tumors. In the context of neurofibromatosis type 1 (NF-1), the management of neurofibromas, malignant peripheral nerve sheath tumors (MPNSTs), and gliomas is challenging due to the limited therapeutic options. Similarly, neurofibromatosis type 2 (NF-2) and schwannomatosis lead to the development of multiple schwannomas and meningiomas within the cranial vault, spinal canal, and extremities. Over the past decade, there has been significant progress in our understanding of the molecular drivers of these tumors and the identification of potential targeted therapies. Here, we welcome papers reviewing the current state of management of these disorders and the advances in characterization of the molecular landscape of the different subtypes afflicting this population.
Prof. Dr. Yasin Temel
Dr. Koos Hovinga
Guest Editors
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Keywords
- neurofibromatosis
- peripheral nerve sheath tumors
- glioblastomas
- meningiomas
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