Special Issue "Cancer Modeling and Network Biology"
Deadline for manuscript submissions: closed (31 August 2021).
Interests: machine learning; mathematical modeling in biology; single cell data analysis; cancer systems biology
Interests: mathematical modeling in biology; boolean network models; biological networks; cancer systems biology
Cancer progression is believed to be driven by abnormal dynamical behavior of signaling and metabolic pathways, transcriptional, or intercellular communication networks. Our knowledge about the structure and the complexity of molecular networks is rapidly growing, allowing the creation of larger-scale mathematical models of cancer-related processes. Modeling cancer networks and using them in multi-omics data analysis can drastically improve our understanding of inter-patient and intra-tumoral heterogeneity at the genetic and epigenetic levels and contribute to prognosis and individualized treatment suggestions. Current challenges in achieving this goal include constructing tissue-specific and high confidence network maps, automating mathematical model creation, choosing the appropriate level of abstraction andand integrating into modeling increasing amounts of omics data related to the cancer biology field, including multi-omics single-cell profiles.
This Special Issue focuses on the latest advances in modeling cancer-related networks and molecular mechanisms, including formalizing the knowledge of molecular networks involved in cancer progression, creating mechanistic and statistical models, and performing network-based analyses of cancer data.
Dr. Andrei Zinovyev
Dr. Laurence Calzone
Dr. Inna Kuperstein
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- comprehensive maps of cancer networks
- dynamical modeling of cancer mechanisms
- multi-scale models in cancer
- single-cell models in cancer
- network-based cancer data analysis
- networks and single-cell omics profiles
- multilayer networks of cancer
- molecular interaction and pathway databases in cancer
- machine learning and network biology in studying cancer