Special Issue "Hormone Involvement in Tissue Development, Physiology, and Oncogenesis"

A special issue of Cancers (ISSN 2072-6694).

Deadline for manuscript submissions: 31 March 2021.

Special Issue Editor

Prof. Dr. Claudio Luparello
Guest Editor
Dipartimento di Scienze e Tecnologie Biologiche, Chimiche, Farmaceutiche (STEBICEF), Edificio 16, Università di Palermo, Viale delle Scienze, Palermo 90128, Italy
Interests: breast cancer cells; hormones; extracellular matrix; enzyme inhibitors; cell proliferation; apoptosis; autophagy; gene expression
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Special Issue Information

Dear Colleagues,

It is well-known that hormones, products of specialized endocrine cells that are spread throughout the body via the bloodstream, control the normal development and growth of a variety of tissues interacting with either surface or intracellular receptors thereby activating signalization pathways. In adult individuals, hormones regulate, integrate, and coordinate a range of different physiological processes that concern virtually all body tissues. On the other hand, excessive or impaired hormonal activities have been proven to increase the risk of oncogenesis in various tissues, such as breast, prostate, uterus, and bone, among others, acting on both the initiation and the promotion stages of cancer etiology. In addition, as result of their de-differentiation, tumor cells themselves can ectopically release hormones and induce the occurrence of paraneoplastic syndromes that can determine the abnormal behavior of organ systems and lead to permanent damages. In this Special issue, researchers are invited to contribute original articles or reviews that report the latest findings on a 360 degree perspective about the molecular and biochemical effects of hormones in developing, developed, and onco-transformed tissues, with a particular focus, although not exclusive, on the comparative analysis of paired tumoral and normal histotypes that might unveil novel metabolic reprogramming routes and potential prognostic biomarkers.

Prof. Dr. Claudio Luparello
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • hormones
  • molecular mechanisms
  • molecular signatures
  • physiological regulation
  • tissue development
  • cell growth
  • cell differentiation
  • tissue oncogenesis
  • metabolic reprogramming
  • prognostic biomarkers
  • hormone pharmacology

Published Papers (1 paper)

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Open AccessEditorial
Hormone Involvement in Tissue Development, Physiology and Oncogenesis: A Preface to the Special Issue
Cancers 2020, 12(9), 2642; https://doi.org/10.3390/cancers12092642 - 16 Sep 2020
Hormones, i [...] Full article
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