Topic Editors

Dipartimento di Scienze e Tecnologie Biologiche, Chimiche, Farmaceutiche (STEBICEF), Edificio 16, Università di Palermo, Viale delle Scienze, 90128 Palermo, Italy
Department of Life Sciences and Systems Biology, University of Torino, Torino, Italy

Molecular and Cellular Aspects of the Beneficial Effects of Natural Products on Chronic Diseases

Abstract submission deadline
31 August 2024
Manuscript submission deadline
31 October 2024
Viewed by

Topic Information

Dear Colleagues,

Chronic diseases account for more than 80% of deaths across the globe. They include hypertension, diabetes, cancer, and cardiovascular, kidney, respiratory, and liver diseases and are often characterized by long-term, low-grade inflammation. Chronic diseases share several common risk factors and underlying determinants, such as low physical activity, obesity, poor diet, disturbed sleep patterns, and stress. These common determinants represent opportunities for effective intervention to improve the disease trajectory toward a more favorable course. Natural products are the oldest forms of medication in human history, and bioactive molecules from natural products can still contribute to new drug development today thanks to their broad chemical and functional diversity. Over the past few decades, several studies have demonstrated that the dietary intake of vegetables, fruits, grains, and legumes rich in bioactive compounds such as flavonoids, anthocyanins, procyanidins, and several others can help combat and prevent various chronic conditions. Considering that oxidative stress and chronic inflammation are the hallmarks of several chronic diseases, promising cellular effects of various bioactive molecules are their antioxidant and anti-inflammatory actions. Other promising properties are the anti-lipogenic and anti-diabetic activities for the treatment of metabolic diseases. However, the detailed effects of bioactive natural compounds at the cellular and molecular levels remain largely unknown. The scope of this Topic is to highlight the recent advances and progress made in the mechanisms of action of bioactive natural compounds against chronic diseases. We welcome original research, reviews, and perspective articles describing in vivo, in vitro, and in silico studies. We look forward to receiving your contributions.

Prof. Dr. Claudio Luparello
Dr. Patrizia Bovolin
Topic Editors


  • chronic diseases
  • bioactive natural compounds
  • cancer
  • metabolic syndrome
  • cardiovascular diseases
  • liver diseases
  • anti-lipogenic
  • antioxidant
  • anti-inflammatory
  • metabolomics/proteomics/transcriptomics

Participating Journals

Journal Name Impact Factor CiteScore Launched Year First Decision (median) APC
5.5 8.3 2011 16.9 Days CHF 2700 Submit
5.2 7.4 2009 17.9 Days CHF 2900 Submit
3.7 - 2013 18.8 Days CHF 1800 Submit
International Journal of Molecular Sciences
5.6 7.8 2000 16.3 Days CHF 2900 Submit
5.9 9.0 2009 14.5 Days CHF 2900 Submit is a multidiscipline platform providing preprint service that is dedicated to sharing your research from the start and empowering your research journey.

MDPI Topics is cooperating with and has built a direct connection between MDPI journals and Authors are encouraged to enjoy the benefits by posting a preprint at prior to publication:

  1. Immediately share your ideas ahead of publication and establish your research priority;
  2. Protect your idea from being stolen with this time-stamped preprint article;
  3. Enhance the exposure and impact of your research;
  4. Receive feedback from your peers in advance;
  5. Have it indexed in Web of Science (Preprint Citation Index), Google Scholar, Crossref, SHARE, PrePubMed, Scilit and Europe PMC.

Published Papers

This Topic is now open for submission.
Back to TopTop