Web-Based and/or Family-Focused Interventions Facilitating Cancer Predisposition Cascade Genetic Screening

Dear Colleagues,

In many countries around the world, privacy laws for the protection of information regarding genetic testing dictate that communication of test results and predisposition to hereditary cancer syndromes (i.e., HBOC and Lynch syndrome) is initiated solely by the person identified with the pathogenic variant and never from the medical clinic. An essentially medical task, i.e., communication of cancer risk and possible testing, relies on mutation carriers as primary communicators with their at-risk relatives. This strategy has significant limitations in both ensuring contact with the appropriate people and the transmission of accurate information and hinders the potential for cancer predisposition cascade genetic testing.

Technology could play a significant role in facilitating communication and access to genetic information and services for families with hereditary predisposition to cancer. This Special Issue of Cancers gives an opportunity to describe recent and original research and/or reviews regarding cancer predisposition cascade genetic screening. We are particularly interested in the development or application of new platforms, and in approaches that address reaching at-risk relatives and facilitating their access to genetic services. (If you would like to discuss an idea for a paper before committing, please contact the Guest Editor or the Editorial Office.)

Prof. Dr. Maria C. Katapodi
Guest Editor

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