Genetic, Epigenetic, and Epitranscriptomic Changes in Lung Cancer
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Pathophysiology".
Deadline for manuscript submissions: 31 March 2025 | Viewed by 8021
Special Issue Editors
Interests: computational biology; ncRNAs; epitranscriptomics; noncoding RNA editing; cancer informatics
Special Issues, Collections and Topics in MDPI journals
Interests: ncRNAs; epitranscriptomics; lung cancer; circulating biomarkers
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Lung cancer remains the leading cause of cancer death worldwide. The World Health Organization (WHO) confirmed that lung cancer occurred in more than two million people in 2020. Lung cancer is mainly classified as non-small cell lung cancer (NSCLC), which represents approximately 85% of all lung cancers, and small cell lung cancer (SCLC), which represents about 15%. Despite advancements in diagnosing and treating lung cancer, patients continue to have a poor prognosis with an overall 5-year survival of ~18%. Despite numerous advances in early detection, targeted therapeutics, and immunotherapy, as well as the employment of new technologies such as next-generation sequencing and bioinformatics resources, the molecular drivers that lead to poor outcomes have yet to be fully understood.
The aim of this Special Issue is to present recent advances in the genomic characterization, epigenetics, and epitranscriptomics of lung cancer. These concepts will be presented in the context of databases and bioinformatics resources to study lung cancer, non-invasive lung cancer biomarkers, molecularly targeted therapies, and immunotherapy.
Dr. Giovanni Nigita
Dr. Mario Acunzo
Dr. Patrick Nana-Sinkam
Guest Editors
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Keywords
- non-small cell lung cancer
- small cell lung cancer
- biology and genomic characterization
- epigenetics and epitranscritomics
- databases and bioinformatics resources
- target drugs
- immunotherapy
- diagnosis and prognosis
- non-invasive biomarkers
- translational research
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