Extracellular Vesicles and Their Roles in Cancer Progression
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 116
Special Issue Editors
Interests: extracellular vesicles; tumor microenvironment; microRNAs; cancer genetics; cancer-associated cachexia
Special Issues, Collections and Topics in MDPI journals
Interests: computational biology; ncRNAs; epitranscriptomics; noncoding RNA editing; cancer informatics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Extracellular vesicles (EVs) have emerged as key mediators of intercellular communication in cancer, playing crucial roles in tumor progression, metastasis, and response to therapy. EVs carry a diverse cargo of bioactive molecules, including proteins, lipids, and nucleic acids, which can influence the tumor microenvironment and serve as potential biomarkers for early detection and disease monitoring.
This Research Topic aims to explore the multifaceted roles of EVs in cancer biology, integrating molecular and computational approaches to deepen our understanding of their function and translational potential. We welcome original research, reviews, and methodological studies on, but not limited to, the following topics:
- EV cargo profiling: The characterization of coding and non-coding RNAs, proteins, and other biomolecules within EVs.
- Multi-omics approaches: The integration of transcriptomics, proteomics, metabolomics, and epigenomics to dissect EV-mediated regulatory mechanisms in cancer.
- EVs in tumor microenvironment interactions: Functional studies on how EVs modulate immune responses, stromal remodeling, and metastasis.
- EV-based biomarkers: The development and validation of EV-derived molecular signatures for cancer diagnosis, prognosis, and therapeutic response prediction.
- Bioinformatics and statistical modeling: Computational strategies for EV data analysis, biomarker discovery, and functional annotation.
With expertise in molecular oncology, RNA biology, and bioinformatics, we aim to curate a collection of high-quality contributions that advance the field of EV research and foster innovative perspectives on their role in cancer progression and clinical applications.
Dr. Federica Calore
Dr. Giovanni Nigita
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- extracellular vesicles
- tumor microenvironment
- biomolecule profiling
- multi-omics
- cancer biomarkers
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
