Advances in Plasmonic Biosensors: From Single to Multiplex Sensing

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Optical and Photonic Biosensors".

Deadline for manuscript submissions: closed (30 April 2024) | Viewed by 2601

Special Issue Editors


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Guest Editor
Integrated Photonics and Applications Centre (InPAC), School of Engineering, RMIT University, Melbourne, VIC 3001, Australia
Interests: optics; nanophotonics; dielectric/plasmonic metasurfaces; optical sensors; photonic crystal fiber; optical devices

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Guest Editor
Integrated Photonics and Applications Centre (InPAC), School of Engineering, RMIT University, Melbourne, VIC 3001, Australia
Interests: silicon photonics; photonic biosensors; CMOS; integrated circuits

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Guest Editor
School of Medicine, Stanford University, Palo Alto, CA 94304, USA
Interests: nanofabrication; bio-inspired photonics; photonic crystal fiber; surface plasmon resonance; biosensing

Special Issue Information

Dear Colleagues,

The development of highly-sensitive miniaturized sensors that allow the real-time quantification of analytes is highly desirable in medical diagnostics, veterinary testing, food safety, and environmental monitoring. Over the last three decades, surface plasmon resonance (SPR) has been considered a key technology for numerous sensing applications. SPR sensors are powerful and effective tools that have been widely used in biosensing, bioimaging, chemical detection, water testing, aqueous sample detection, food safety, environment monitoring, biological analyte detection and gas detection. SPR-based sensors have received extreme interest as they offer high sensitivity and better detection accuracy of unknown analytes. At present, avoiding false-positive responses is another important issue. Due to their highly sensitive responsiveness, plasmonic-sensor-based multi-analyte detection is another important direction which can significantly reduce false-positive responses and accelerate the detection process. 

Dr. Rifat Ahmmed Aoni
Dr. Guanghui Ren
Dr. Rajib Ahmed
Guest Editors

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Keywords

  • plasmonic biosensors
  • nanophotonic biosensors
  • metasurfaces/metamaterials for biochemical sensors
  • optical biosensors
  • SERS
  • thermoplasmonics
  • microfluidics for biosensors
  • biophotonics
  • multiplex sensors
  • multi-analyte detection
  • two-dimensional plasmonic materials for biochemical sensing
  • artificial-intelligence-enabled biochemical sensors

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Published Papers (1 paper)

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Research

11 pages, 4145 KiB  
Article
A SERS Composite Hydrogel Device for Point-of-Care Analysis of Neurotransmitter in Whole Blood
by Lei Wu, Xuefeng Liu, Shenfei Zong, Zhuyuan Wang and Yiping Cui
Biosensors 2023, 13(6), 611; https://doi.org/10.3390/bios13060611 - 2 Jun 2023
Cited by 4 | Viewed by 1673
Abstract
Point-of-care analysis of neurotransmitters in body fluids plays a significant role in healthcare improvement. Conventional approaches are limited by time-consuming procedures and usually require laboratory instruments for sample preparation. Herein, we developed a surface enhanced Raman spectroscopy (SERS) composite hydrogel device for the [...] Read more.
Point-of-care analysis of neurotransmitters in body fluids plays a significant role in healthcare improvement. Conventional approaches are limited by time-consuming procedures and usually require laboratory instruments for sample preparation. Herein, we developed a surface enhanced Raman spectroscopy (SERS) composite hydrogel device for the rapid analysis of neurotransmitters in whole blood samples. The PEGDA/SA composite hydrogel enabled fast separation of small molecules from the complex blood matrix, while the plasmonic SERS substrate allowed for the sensitive detection of target molecules. 3D printing was employed to integrate the hydrogel membrane and the SERS substrate into a systematic device. The sensor achieved highly sensitive detection of dopamine in whole blood samples with a limit of detection down to 1 nM. The whole detection process from sample preparation to SERS readout can be finished within 5 min. Due to the simple operation and rapid response, the device shows great potential in point-of-care diagnosis and the monitoring of neurological and cardiovascular diseases and disorders. Full article
(This article belongs to the Special Issue Advances in Plasmonic Biosensors: From Single to Multiplex Sensing)
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