Biological Biomaterials for Regenerative Medicine

Dear Colleagues,

Biologically derived biomaterials present unique and well-designed molecular structures with intrinsic affinities to the complex networks involved in tissue homeostasis. Consequently, biomaterial-based engineering approaches hold tremendous potential to regenerate tissues and organs damaged by trauma or disease. The rational design of those biomaterial substrates with adequate structural (e.g., surface topography, size, and shape) and/or chemical (e.g., drugs and cell signaling molecules) cues will allow driving homeostasis and functional tissue regeneration. Indeed, the ability of the engineered substrates to combine the function and fate of endogenous (e.g., endothelial and immune cells) and exogenous stem or progenitor cells can advance tissue engineering therapies into routine clinical practice.

The aim of this Special Issue is to publish original research articles in advanced and effective regenerative medicine strategies. Review articles critically and systematically treating the published research and forecasting future avenues in the field and highlighting the current challenges that hinder the translation of regenerative medicine strategies into clinical practice will be considered for inclusion in this Special Issue.

Prof. Dr. Antonella Motta
Prof. Dr. Rui L. Reis
Prof. Dr. Nuno M. Neves
Dr. Helena Ferreira
Guest Editors

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