Special Issue "Bacterial RNA Polymerase"
A special issue of Biomolecules (ISSN 2218-273X).
Deadline for manuscript submissions: closed (31 January 2015).
Interests: bacterial RNA polymerase; transcription regulation; bacteriophages; bacterial stress response; bacterial virulence gene expression and regulation
Interests: RNA polymerase; transcription initiation and activation; bacteriophage; bacterial virulence gene expression; response regulators
A single, large, and multi-subunit enzyme called RNA polymerase (RNAP) accomplishes all RNA syntheses in bacteria. Therefore, the bacterial RNAP represents a nexus for the regulation of bacterial gene expression and is frequently the target of sophisticated signal transduction pathways that serve to link environmental, metabolic and developmental cues to the regulation of gene expression at the transcriptional level. The bacterial RNAP is also a validated antibiotic target and is inhibited by the rifampicin-class of antibiotics. This Special Issue of Biomolecules contains invited reviews from leading scientists in the field on recent advances on the crystallographic, biochemical, single-molecule biophysical and systems level descriptions of the bacterial RNAP and on efforts to develop novel antibiotic-like compounds to inhibit this essential bacterial enzyme.
Prof. Dr. Sivaramesh Wigneshweraraj
Dr. Deborah M. Hinton
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- RNA polymerase
- transcription regulation
- sigma factors
- transcription regulators