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Structural Biology of Bacterial RNA Polymerase
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Biomolecules 2015, 5(2), 1012-1019;

A Perspective on the Enhancer Dependent Bacterial RNA Polymerase

Department of Life Sciences, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, London SW7 2AZ, UK
Author to whom correspondence should be addressed.
Academic Editors: Sivaramesh Wigneshweraraj and Deborah M. Hinton
Received: 2 April 2015 / Accepted: 15 May 2015 / Published: 21 May 2015
(This article belongs to the Special Issue Bacterial RNA Polymerase)
Full-Text   |   PDF [941 KB, uploaded 21 May 2015]   |  


Here we review recent findings and offer a perspective on how the major variant RNA polymerase of bacteria, which contains the sigma54 factor, functions for regulated gene expression. We consider what gaps exist in our understanding of its genetic, biochemical and biophysical functioning and how they might be addressed. View Full-Text
Keywords: RNA polymerase; Sigma54; transcription; AAA+ ATPase RNA polymerase; Sigma54; transcription; AAA+ ATPase

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Zhang, N.; Buck, M. A Perspective on the Enhancer Dependent Bacterial RNA Polymerase. Biomolecules 2015, 5, 1012-1019.

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