A Perspective on the Enhancer Dependent Bacterial RNA Polymerase
by
Nan Zhang and Martin Buck *
Nan Zhang and Martin Buck *
Department of Life Sciences, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, London SW7 2AZ, UK
*
Author to whom correspondence should be addressed.
Academic Editors: Sivaramesh Wigneshweraraj and Deborah M. Hinton
Biomolecules 2015, 5(2), 1012-1019; https://doi.org/10.3390/biom5021012
Received: 2 April 2015 / Accepted: 15 May 2015 / Published: 21 May 2015
(This article belongs to the Special Issue Bacterial RNA Polymerase)
Here we review recent findings and offer a perspective on how the major variant RNA polymerase of bacteria, which contains the sigma54 factor, functions for regulated gene expression. We consider what gaps exist in our understanding of its genetic, biochemical and biophysical functioning and how they might be addressed.
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Keywords:
RNA polymerase; Sigma54; transcription; AAA+ ATPase
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MDPI and ACS Style
Zhang, N.; Buck, M. A Perspective on the Enhancer Dependent Bacterial RNA Polymerase. Biomolecules 2015, 5, 1012-1019.
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