Announcements

As all of the articles published in our journal are open access, you have free and unlimited access to the full text. We welcome you to read our most highly cited papers published in 2022 and 2023, which are listed below.

1. “NAFLD: Mechanisms, Treatments, and Biomarkers”
by Fatiha Nassir
Biomolecules 2022, 12(6), 824; https://doi.org/10.3390/biom12060824
Full text available online: https://www.mdpi.com/2218-273X/12/6/824

2. “Nano-Based Approved Pharmaceuticals for Cancer Treatment: Present and Future Challenges”
by Francisco Rodríguez, Pablo Caruana, Noa De la Fuente, Pía Español, María Gámez, Josep Balart, Elisa Llurba, Ramón Rovira, Raúl Ruiz, Cristina Martín-Lorente et al.
Biomolecules2022, 12(6), 784; https://doi.org/10.3390/biom12060784
Full text available online: https://www.mdpi.com/2218-273X/12/6/784

3. “Biological Effects of Human Exposure to Environmental Cadmium”
by Massimiliano Peana, Alessio Pelucelli, Christos T. Chasapis, Spyros P. Perlepes, Vlasoula Bekiari, Serenella Medici and Maria Antonietta Zoroddu 
Biomolecules2023,13(1), 36; https://doi.org/10.3390/biom13010036
Full text available online: https://www.mdpi.com/2218-273X/13/1/36

4. “Oxidative Stress and NRF2/KEAP1/ARE Pathway in Diabetic Kidney Disease (DKD): New Perspectives”
by Daniela Maria Tanase, Evelina Maria Gosav, Madalina Ioana Anton, Mariana Floria, Petronela Nicoleta Seritean Isac, Loredana Liliana Hurjui, Claudia Cristina Tarniceriu, Claudia Florida Costea, Manuela Ciocoiu and Ciprian Rezus 
Biomolecules2022, 12(9), 1227; https://doi.org/10.3390/biom12091227
Full text available online: https://www.mdpi.com/2218-273X/12/9/1227

5. “The Role of Tryptophan Dysmetabolism and Quinolinic Acid in Depressive and Neurodegenerative Diseases”
by Knut Hestad, Jan Alexander, Helge Rootwelt and Jan O. Aaseth 
Biomolecules2022, 12(7), 998; https://doi.org/10.3390/biom12070998
Full text available online: https://www.mdpi.com/2218-273X/12/7/998

6. “Recent Advances of Tubulin Inhibitors Targeting the Colchicine Binding Site for Cancer Therapy”
by Mohammed Hawash 
Biomolecules2022, 12(12), 1843; https://doi.org/10.3390/biom12121843
Full text available online: https://www.mdpi.com/2218-273X/12/12/1843

7. “Cerebral Iron Deposition in Neurodegeneration”
by Petr Dusek, Tim Hofer, Jan Alexander, Per M. Roos and Jan O. Aaseth 
Biomolecules2022, 12(5), 714; https://doi.org/10.3390/biom12050714
Full text available online: https://www.mdpi.com/2218-273X/12/5/714

8. “Progesterone as an Anti-Inflammatory Drug and Immunomodulator: New Aspects in Hormonal Regulation of the Inflammation”
by Tatiana A. Fedotcheva, Nadezhda I. Fedotcheva and Nikolai L. Shimanovsky
Biomolecules2022, 12(9), 1299; https://doi.org/10.3390/biom12091299
Full text available online: https://www.mdpi.com/2218-273X/12/9/1299

9. “The Impact of Zinc and Zinc Homeostasis on the Intestinal Mucosal Barrier and Intestinal Diseases”
by Yan Wan and Bingkun Zhang 
Biomolecules2022, 12(7), 900; https://doi.org/10.3390/biom12070900
Full text available online: https://www.mdpi.com/2218-273X/12/7/900

10. “The Role of JAK/STAT Pathway in Fibrotic Diseases: Molecular and Cellular Mechanisms”
by Jia Liu, Faping Wang and Fengming Luo 
Biomolecules2023, 13(1), 119; https://doi.org/10.3390/biom13010119
Full text available online: https://www.mdpi.com/2218-273X/13/1/119

The 2024 International Conference of the Korean Society for Molecular and Cellular Biology will be held from 8 to 11 October 2024, in Jeju, Republic of Korea. The conference is organized by the Korean Society for Molecular and Cellular Biology, and promises a rich tapestry of scholarly exchange across various disciplines within biological and biomedical sciences.

The conference will feature four top keynote speakers in the field of life sciences, including two Nobel Prize winners, and scientists from more than thirty countries around the world participating in more than twenty scientific sessions on a variety of topics. The agenda includes symposiums showcasing pioneering research in life sciences, dedicated sessions for young academics, such as graduate students, postdoctoral researchers, and research professors, and a Bio Job Fair.

The following MDPI journals will be represented at the conference:

• International Journal of Molecular Sciences;
• Antioxidants;
• Biophysica;
• Current Issues in Molecular Biology;
• Kinases and Phosphatases;
• Metabolites;
• Microorganisms;
• Proteomes;
• Bioengineering;
• Biomedicines;
• BioMed;
• Biomolecules;
• Cancers;
• Genes;
• Journal of Molecular Pathology;
• Organoids;
• Plants;
• Non-Coding RNA;
• Sci;
• Journal of Fungi.

If you are attending this conference, please feel free to start an online conversation with us. Our delegates look forward to meeting you in person at booth #99 and answering any questions that you may have. For more information about the conference, please visit the following link: https://www.ksmcb.or.kr/icksmcb2024/main.html.

MDPI’s Young Investigator Awards recognize promising early career scientists, acknowledge their contributions, and foster collaboration within the scientific community. We are proud to announce the recipients for 2023, who were carefully selected by the journals’ esteemed Award Evaluation Committee.

We extend our heartfelt congratulations to the 79 winners of MDPI’s 2023 Young Investigator Awards for their excellent contributions in their research field. We look forward to seeing these rising stars continue to contribute to the advancement of science.

MDPI will continue to support and recognize the academic community. To explore details about the awardees by field, please visit the individual pages listed below:

Congratulations to all the winners for their exceptional contributions and dedication to advancing scientific research.

About MDPI Awards:
To support the academic community, particularly young researchers, and to enhance communication among scientists, MDPI journals regularly offer various awards to researchers in specific fields. These awards, serving as a source of inspiration and recognition, help to elevate the profiles of talented individuals who have made outstanding achievements and are making significant contributions to advancements in their respective fields.

To find out more about MDPI awards, please click here.

As all of the articles published in our journal Biomolecules (ISSN: 2218-273X) are open access, you have free and unlimited access to the full texts. We welcome you to read our most highly cited papers published in 2022 and 2023, which are listed below:

1. “Development of Biodegradable Polymeric Stents for the Treatment of Cardiovascular Diseases”
by Yihong Shen, Xiao Yu, Jie Cui, Fan Yu, Mingyue Liu, Yujie Chen, Jinglei Wu, Binbin Sun and Xiumei Mo
Biomolecules 2022, 12(9), 1245; https://doi.org/10.3390/biom12091245
Full text available online: https://www.mdpi.com/2218-273X/12/9/1245

2. “Advances in the Application of Electrospun Drug-Loaded Nanofibers in the Treatment of Oral Ulcers”
by Yangqi Zhou, Menglong Wang, Chao Yan, Hui Liu and Deng-Guang Yu
Biomolecules 2022, 12(9), 1254; https://doi.org/10.3390/biom12091254
Full text available online: https://www.mdpi.com/2218-273X/12/9/1254

3. ”Design of Biocompatible Chitosan/Polyaniline/Laponite Hydrogel with Photothermal Conversion Capability”
by Liying Zhang, Gao He, Yang Yu, Yu Zhang, Xiang Li and Shige Wang
Biomolecules 2022, 12(8), 1089; https://doi.org/10.3390/biom12081089
Full text available online: https://www.mdpi.com/2218-273X/12/8/1089

4. ”A Review on Electrospun Poly(amino acid) Nanofibers and Their Applications of Hemostasis and Wound Healing”
by Yuexin Ji, Wenliang Song, Lin Xu, Deng-Guang Yu and Sim Wan Annie Bligh
Biomolecules 2022, 12(6), 794; https://doi.org/10.3390/biom12060794
Full text available online: https://www.mdpi.com/2218-273X/12/6/794

5. ”Silk Fibroin Biomaterials and Their Beneficial Role in Skin Wound Healing”
by Łukasz Mazurek, Mateusz Szudzik, Mateusz Rybka and Marek Konop
Biomolecules 2022, 12(12), 1852; https://doi.org/10.3390/biom12121852
Full text available online: https://www.mdpi.com/2218-273X/12/12/1852

6. ”Recent Developments in Biopolymer-Based Hydrogels for Tissue Engineering Applications”
by Rikako Hama, Anudari Ulziibayar, James W. Reinhardt, Tatsuya Watanabe, John Kelly and Toshiharu Shinoka
Biomolecules 2023, 13(2), 280; https://doi.org/10.3390/biom13020280
Full text available online: https://www.mdpi.com/2218-273X/13/2/280

7. ”Electrospun Zein/Polyoxyethylene Core-Sheath Ultrathin Fibers and Their Antibacterial Food Packaging Applications”
by Wenlai Jiang, Ping Zhao, Wenliang Song, Menglong Wang and Deng-Guang Yu
Biomolecules 2022, 12(8), 1110; https://doi.org/10.3390/biom12081110
Full text available online: https://www.mdpi.com/2218-273X/12/8/1110

8. ”Advances in the Preparation of Nanofiber Dressings by Electrospinning for Promoting Diabetic Wound Healing”
by Yukang Liu, Chaofei Li, Zhangbin Feng, Biao Han, Deng-Guang Yu and Ke Wang
Biomolecules 2022, 12(12), 1727; https://doi.org/10.3390/biom12121727
Full text available online: https://www.mdpi.com/2218-273X/12/12/1727

9. ”Recent Progress of Electrospun Herbal Medicine Nanofibers”
by Hang Liu, Yubin Bai, Chang Huang, Ying Wang, Yuexin Ji, Yutong Du, Lin Xu, Deng-Guang Yu and Sim Wan Annie Bligh
Biomolecules 2023, 13(1), 184; https://doi.org/10.3390/biom13010184
Full text available online: https://www.mdpi.com/2218-273X/13/1/184

As all of the articles published in our journal Biomolecules (ISSN: 2218-273X) are open access, you have free and unlimited access to the full texts. We welcome you to read our most highly cited papers published in 2022 and 2023, which are listed below:

1. “The Degradation of Hyaluronan in the Skin”
by Petra Žádníková, Romana Šínová, Vojtěch Pavlík, Matěj Šimek, Barbora Šafránková, Martina Hermannová, Kristina Nešporová and Vladimír Velebný
Biomolecules 2022, 12(2), 251; https://doi.org/10.3390/biom12020251
Full text available online: https://www.mdpi.com/2218-273X/12/2/251

2. “Role of EPA in Inflammation: Mechanisms, Effects, and Clinical Relevance”
by Rosalia Crupi and Salvatore Cuzzocrea
Biomolecules 2022, 12(2), 242; https://doi.org/10.3390/biom12020242
Full text available online: https://www.mdpi.com/2218-273X/12/2/242

3. “The Effect of Electrical Stimulation on Nerve Regeneration Following Peripheral Nerve Injury”
by Luke Juckett, Tiam Mana Saffari, Benjamin Ormseth, Jenna-Lynn Senger and Amy M. Moore
Biomolecules 2022, 12(12), 1856; https://doi.org/10.3390/biom12121856
Full text available online: https://www.mdpi.com/2218-273X/12/12/1856

4. “Homocysteine, Vitamins B6 and Folic Acid in Experimental Models of Myocardial Infarction and Heart Failure—How Strong Is That Link?”
by Zorislava Bajic, Tanja Sobot, Ranko Skrbic, Milos P. Stojiljkovic, Nenad Ponorac, Amela Matavulj  and Dragan M. Djuric
Biomolecules 2022, 12(4), 536; https://doi.org/10.3390/biom12040536
Full text available online: https://www.mdpi.com/2218-273X/12/4/536

5. “Advanced Strategies for Therapeutic Targeting of Wild-Type and Mutant p53 in Cancer”
by Shengliang Zhang, Lindsey Carlsen, Liz Hernandez Borrero, Attila A. Seyhan, Xiaobing Tian and Wafik S. El-Deiry
Biomolecules 2022, 12(4), 548; https://doi.org/10.3390/biom12040548
Full text available online: https://www.mdpi.com/2218-273X/12/4/548

6. “Louis Pasteur: Between Myth and Reality”
by Jean-Marc Cavaillon and Sandra Legout
Biomolecules 2022, 12(4), 596; https://doi.org/10.3390/biom12040596
Full text available online: https://www.mdpi.com/2218-273X/12/4/596

7. “Delayed Onset Muscle Soreness and Critical Neural Microdamage-Derived Neuroinflammation”
by Balázs Sonkodi
Biomolecules 2022, 12(9), 1207; https://doi.org/10.3390/biom12091207
Full text available online: https://www.mdpi.com/2218-273X/12/9/1207

8. “The Challenges and Prospects of p53-Based Therapies in Ovarian Cancer”
by Bryce Wallis, Katherine Redd Bowman, Phong Lu and Carol S. Lim
Biomolecules 2023, 13(1), 159; https://doi.org/10.3390/biom13010159
Full text available online: https://www.mdpi.com/2218-273X/13/1/159

9. “Cross-Talk between p53 and Wnt Signaling in Cancer”
by Qiyun Xiao, Johannes Werner, Nachiyappan Venkatachalam, Kim E. Boonekamp, Matthias P. Ebert and Tianzuo Zhan
Biomolecules 2022, 12(3), 453; https://doi.org/10.3390/biom12030453
Full text available online: https://www.mdpi.com/2218-273X/12/3/453

As all of the articles published in our journal Biomolecules (ISSN: 2218-273X) are open access, you have free and unlimited access to the full texts. We welcome you to read our most highly cited papers published in 2022 and 2023, which are listed below:

1. “Advanced Glycation End Products and Diabetes Mellitus: Mechanisms and Perspectives”
by Mariyam Khalid, Georg Petroianu and Abdu Adem
Biomolecules 2022, 12(4), 542; https://doi.org/10.3390/biom12040542
Full text available online: https://www.mdpi.com/2218-273X/12/4/542

2. “Metallothionein and Cadmium Toxicology—Historical Review and Commentary”
by Monica Nordberg and Gunnar F. Nordberg
Biomolecules 2022, 12(3), 360; https://doi.org/10.3390/biom12030360
Full text available online: https://www.mdpi.com/2218-273X/12/3/360

3. “Adenosine-Metabolizing Enzymes, Adenosine Kinase and Adenosine Deaminase, in Cancer”
by Galina Zhulai, Eugenia Oleinik, Mikhail Shibaev and Kirill Ignatev
Biomolecules 2022, 12(3), 418; https://doi.org/10.3390/biom12030418
Full text available online: https://www.mdpi.com/2218-273X/12/3/418

4. “Current and Novel Therapeutic Approaches for Treatment of Neovascular Age-Related Macular Degeneration”
by Reem H. ElSheikh, Muhammad Z. Chauhan and Ahmed B. Sallam
Biomolecules 2022, 12(11), 1629; https://doi.org/10.3390/biom12111629
Full text available online: https://www.mdpi.com/2218-273X/12/11/1629

5. “Bcl-2 Family Members and the Mitochondrial Import Machineries: The Roads to Death”
by Lisenn Lalier, François Vallette François Vallette and Stéphen Manon
Biomolecules 2022, 12(2), 162; https://doi.org/10.3390/biom12020162
Full text available online: https://www.mdpi.com/2218-273X/12/2/162

6. “The Disordered Dehydrin and Its Role in Plant Protection: A Biochemical Perspective”
by Margaret A. Smith and Steffen P. Graether
Biomolecules 2022, 12(2), 294; https://doi.org/10.3390/biom12020294
Full text available online: https://www.mdpi.com/2218-273X/12/2/294

7. “Co-Stimulatory Receptor Signaling in CAR-T Cells”
by Mackenzie M. Honikel and Scott H. Olejniczak
Biomolecules 2022, 12(9), 1303; https://doi.org/10.3390/biom12091303
Full text available online: https://www.mdpi.com/2218-273X/12/9/1303

8. “Galactosemia: Biochemistry, Molecular Genetics, Newborn Screening, and Treatment”
by Mariangela Succoio, Rosa Sacchettini, Alessandro Rossi, Giancarlo Parenti and Margherita Ruoppolo
Biomolecules 2022, 12(7), 968; https://doi.org/10.3390/biom12070968
Full text available online: https://www.mdpi.com/2218-273X/12/7/968

9. “Molecular Recognition of Proteins through Quantitative Force Maps at Single Molecule Level”
by Carlos Marcuello, Rocío de Miguel and Anabel Lostao
Biomolecules 2022, 12(4), 594; https://doi.org/10.3390/biom12040594
Full text available online: https://www.mdpi.com/2218-273X/12/4/594

10. “Cellular Senescence in Intervertebral Disc Aging and Degeneration: Molecular Mechanisms and Potential Therapeutic Opportunities”
by Prashanta Silwal, Allison M. Nguyen-Thai, Haneef Ahamed Mohammad, Yanshan Wang, Paul D. Robbins, Joon Y. Lee and Nam V. Vo
Biomolecules 2023, 13(4), 686; https://doi.org/10.3390/biom13040686
Full text available online: https://www.mdpi.com/2218-273X/13/4/686

As all of the articles published in our journal Biomolecules (ISSN: 2218-273X) are open access, you have free and unlimited access to the full text. We welcome you to read our most highly cited papers published in 2022 and 2023, which are listed below:

1. “Boosting the Full Potential of PyMOL with Structural Biology Plugins”
by Serena Rosignoli and Alessandro Paiardini
Biomolecules 2022, 12(12), 1764; https://doi.org/10.3390/biom12121764
Full text available online: https://www.mdpi.com/2218-273X/12/12/1764

2. “Calcium Overload and Mitochondrial Metabolism”
by Lauren L. Walkon, Jasiel O. Strubbe-Rivera and Jason N. Bazil
Biomolecules 2022, 12(12), 1891; https://doi.org/10.3390/biom12121891
Full text available online: https://www.mdpi.com/2218-273X/12/12/1891

3. “Benchmarking the Accuracy of AlphaFold 2 in Loop Structure Prediction”
by Amy O. Stevens and Yi He
Biomolecules 2022, 12(7), 985; https://doi.org/10.3390/biom12070985
Full text available online: https://www.mdpi.com/2218-273X/12/7/985

4. “Protein Data Bank: A Comprehensive Review of 3D Structure Holdings and Worldwide Utilization by Researchers, Educators, and Students”
by Stephen K. Burley, Helen M. Berman, Jose M. Duarte, Zukang Feng, Justin W. Flatt, Brian P. Hudson, Robert Lowe, Ezra Peisach, Dennis W. Piehl, Yana Rose et al.
Biomolecules 2022, 12(10), 1425; https://doi.org/10.3390/biom12101425
Full text available online: https://www.mdpi.com/2218-273X/12/10/1425

5. “Predicting miRNA-Disease Association Based on Neural Inductive Matrix Completion with Graph Autoencoders and Self-Attention Mechanism”
by Chen Jin, Zhuangwei Shi, Ken Lin and Han Zhang
Biomolecules 2022, 12(1), 64; https://doi.org/10.3390/biom12010064
Full text available online: https://www.mdpi.com/2218-273X/12/1/64

6. “ECMpy, a Simplified Workflow for Constructing Enzymatic Constrained Metabolic Network Model”
by Zhitao Mao, Xin Zhao, Xue Yang, Peiji Zhang, Jiawei Du, Qianqian Yuan and Hongwu Ma
Biomolecules 2022, 12(1), 65; https://doi.org/10.3390/biom12010065
Full text available online: https://www.mdpi.com/2218-273X/12/1/65

7. “The Epigenetic Dimension of Protein Structure Is an Intrinsic Weakness of the AlphaFold Program”
by Fodil Azzaz, Nouara Yahi, Henri Chahinianand Jacques Fantini
Biomolecules 2022, 12(10), 1527; https://doi.org/10.3390/biom12101527
Full text available online: https://www.mdpi.com/2218-273X/12/10/1527

8. “The Metabolomic Approach for the Screening of Endometrial Cancer: Validation from a Large Cohort of Women Scheduled for Gynecological Surgery”
by Jacopo Troisi, Antonio Mollo, Martina Lombardi, Giovanni Scala, Sean M. Richards, Steven J. K. Symes, Antonio Travaglino, Daniele Neola, Umberto de Laurentiis, Luigi Insabato et al.
Biomolecules 2022, 12(9), 1229; https://doi.org/10.3390/biom12091229
Full text available online: https://www.mdpi.com/2218-273X/12/9/1229

9. “Saquinavir: From HIV to COVID-19 and Cancer Treatment”
by Mariana Pereira and Nuno Vale
Biomolecules 2022, 12(7), 944; https://doi.org/10.3390/biom12070944
Full text available online: https://www.mdpi.com/2218-273X/12/7/944

10. “Bioinformatics Prediction and Experimental Validation Identify a Novel Cuproptosis-Related Gene Signature in Human Synovial Inflammation during Osteoarthritis Progression”
by Wenjuan Wang, Ziyi Chen and Yinghui Hua
Biomolecules 2023, 13(1), 127; https://doi.org/10.3390/biom13010127
Full text available online: https://www.mdpi.com/2218-273X/13/1/127

Prof. Dr. Benoit Coulombe is a full research professor in the Department of Biochemistry and Molecular Medicine, Université de Montréal, Canada. His lab, located at the Institut de Recherches Cliniques de Montréal (IRCM), is developing state-of-the-art methods for high-sensitivity profiling of the human proteome at single-cell resolutions. More specifically, they aim to understand the folding and assembly of protein complexes by the HSP90/PAQosome chaperone machinery, as well as its dysregulation in various diseases.

The following is a short Q&A with Prof. Dr. Benoit Coulombe, who shared his vision for the journal with us, as well as his views on the research area and open access publishing:

1. What appealed to you about the journal that made you want to become its Section Editor-in-Chief?
Two things: (1) the highly rigorous and rapid review process, and (2) the open access approach.

2. What is your vision for this Section?
Proteins are the main functional actors of the cell, and their dysfunctions cause diseases. This makes this Section particularly important.

3. What does the future of this field of research look like?
This field is constantly expanding. Most significant are the new technology developments dealing with proteomics and structural modeling (AlphaFold).

4. Do you have any suggestions for young researchers in this field?
The pursuit of innovation is key for humanity.

5. What do you think of the development of open access publishing in the publishing field?
The development of OA is going in the right direction and journals like Biomolecules are important to push in this direction

We warmly welcome Prof. Dr. Benoit Coulombe as Section Editor-in-Chief for “Biomacromolecules: Proteins”, and we look forward to him leading Biomolecules to achieve many more milestones.

MDPI will attend the Biomolecular Horizons 2024 Congress, held from 22 to 26 September 2024 in Melbourne, Australia. This important forum will bring together three prestigious congresses, each with a strong history of attracting the bioscience and biotechnology communities to discuss and examine the latest developments and research:

• 26th Congress of the International Union of Biochemistry and Molecular Biology (IUBMB);
• 17th Congress of the Federation of Asian & Oceanian Biochemists & Molecular Biologists (FAOBMB);
• 22nd ComBio Conference (ComBio).

The overarching theme of the Biomolecular Horizons 2024 (BMH2024) Congress is “Discover, Create, Innovate”, which will be examined across the following key themes:

• Cell, Developmental and Stem Cell Biology;
• Biotechnology and Synthetic Biology;
• Microbial World;
• Cell Signalling and Metabolism;
• Genomics, Gene Regulation and Epigenetics;
• Bioinformatics, Computational Biology and Omics;
• Structural Biology and Biophysics;
• Molecular Basis of Disease;
• Molecular Physiology;
• Education.

The following MDPI journals will be represented:

• International Journal of Molecular Sciences;
• Biomolecules;
• Applied Biosciences;
• BioMedInformatics;
• Biomedicines;
• Cells;
• Applied Microbiology;
• BioTech;
• Biologics;
• Current Issues in Molecular Biology;
• Epigenomes;
• Genes;
• Journal of Developmental Biology;
• Journal of Molecular Pathology;
• Methods and Protocols;
• Muscles;
• Organoids;
• Signals;
• SynBio;
• Cardiogenetics.

If you are planning to attend the above conference, please feel free to stop by our booth. Our delegates look forward to meeting you in person to answer any questions that you may have. For more information about the conference, please visit the following link: https://www.bmh2024.com/.