Recent Advances in Wearable Bioelectronics in Healthcare/Medical Devices

A special issue of Biomimetics (ISSN 2313-7673). This special issue belongs to the section "Biomimetic Design, Constructions and Devices".

Deadline for manuscript submissions: 10 September 2025 | Viewed by 599

Special Issue Editor


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Guest Editor
Department of Bioengineering, Lehigh University, Bethlehem, PA 18015, USA
Interests: wearable tech; digital health; bioelectronics

Special Issue Information

Dear Colleagues,

Recent advances in bioelectronics and wearable devices have significantly transformed healthcare, offering innovative solutions for monitoring, diagnosing, and treating various health conditions. Bioelectronic technologies, which integrate biology with electronics, enable precise interactions with biological systems at the molecular and cellular levels. One notable development is flexible, skin-like sensors that monitor vital signs such as heart rate, blood pressure, glucose levels, and even biomarkers for diseases like Parkinson's or Alzheimer’s. These devices leverage advanced materials, such as stretchable polymers and conductive hydrogels, to ensure comfort and durability for long-term wear. Wearable devices, powered by artificial intelligence (AI) and machine learning, now analyze real-time data to detect anomalies and predict health risks, enabling early intervention. The integration of wireless communication technologies, including Bluetooth and 5G, facilitates seamless data sharing between patients and healthcare providers, improving telemedicine capabilities. Implantable bioelectronic devices, such as neural interfaces, are also advancing, offering hope for restoring motor function in paralyzed individuals or managing chronic pain through electrical stimulation. Furthermore, energy harvesting innovations, like sweat-powered or body-heat-based systems, enhance the sustainability of these devices. As bioelectronics and wearable healthcare technologies continue to evolve, they promise a future of personalized, non-invasive, and connected healthcare solutions, fundamentally reshaping patient care.

Dr. Dhruv R. Seshadri
Guest Editor

Manuscript Submission Information

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Keywords

  • wearable sensors
  • bioelectronics
  • digital therapeutics
  • digital biomarkers
  • remote monitoring
  • human performance
  • epidermal electronics

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Published Papers (1 paper)

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Research

18 pages, 5498 KiB  
Article
Development and Evaluation of a Novel Upper-Limb Rehabilitation Device Integrating Piano Playing for Enhanced Motor Recovery
by Xin Zhao, Ying Zhang, Yi Zhang, Peng Zhang, Jinxu Yu and Shuai Yuan
Biomimetics 2025, 10(4), 200; https://doi.org/10.3390/biomimetics10040200 - 25 Mar 2025
Viewed by 406
Abstract
This study developed and evaluated a novel upper-limb rehabilitation device that integrates piano playing into task-oriented occupational therapy, addressing the limitations of traditional continuous passive motion (CPM) training in patient engagement and functional recovery. The system features a bi-axial sliding platform for precise [...] Read more.
This study developed and evaluated a novel upper-limb rehabilitation device that integrates piano playing into task-oriented occupational therapy, addressing the limitations of traditional continuous passive motion (CPM) training in patient engagement and functional recovery. The system features a bi-axial sliding platform for precise 61-key positioning and a ten-link, four-loop robotic hand for key striking. A hierarchical control framework incorporates MIDI-based task mapping, finger optimization using an improved Hungarian algorithm, and impedance–admittance hybrid control for adaptive force–position modulation. An 8-week randomized controlled trial demonstrated that the experimental group significantly outperformed the control group, with a 74.7% increase in Fugl–Meyer scores (50.5 ± 2.5), a 14.6-point improvement in the box and block test (BBT), a 20.2-s reduction in nine-hole peg test (NHPT) time, and a 72.6% increase in rehabilitation motivation scale (RMS) scores (55.4 ± 3.8). The results indicate that combining piano playing with robotic rehabilitation enhances neuroplasticity and engagement, significantly improving motor function, daily activity performance, and rehabilitation adherence. This mechanical-control synergy introduces a new paradigm for music-interactive rehabilitation, with potential applications in home-based remote therapy and multimodal treatment integration. Full article
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