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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Chronic Vascular Impairment in Heart, Brain, and Kidney Disorders: Molecular Mechanisms and Therapeutic Strategies

edited by

Mahdi O. Garelnabi

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2429 | Submission Open

Keywords: atherosclerosis; lipoprotein; inflammation; antioxidants; oxidative stress; cardiovascular diseases; neurodegenerative disorders; blood–brain barrier; stroke; Alzheimer's disease; kidney

(This special issue belongs to the Section Cell Biology and Pathology)

Advances in Skin Tumors: From Pathogenesis to Treatment Strategies

edited by Zhongxin Yu and Sepideh Nikki Asadbeigi

submission deadline 31 Dec 2026 | 1 articles | Viewed by 2422 | Submission Open

Keywords: melanoma skin; tumor epigenetic alterations; genetic mutations; tumor microenvironment immunotherapy; targeted therapy; nanomedicine

(This special issue belongs to the Section Cancer Biology and Oncology)

Digestive Disorders: Translation and Bridging the Gap Between Research, Diagnosis, and Treatment (2nd Edition)

edited by Goran Poropat and Goran Hauser

submission deadline 31 Dec 2026 | 1 articles | Viewed by 2399 | Submission Open

Keywords: acute pancreatitis; clinical nutrition; metabolic disorders; NAFLD; obesity; DGBA; gut microbiota

(This special issue belongs to the Section Molecular and Translational Medicine)

Chronic Obstructive Pulmonary Disease: From Mechanisms to Personalized Therapeutic Strategies

edited by

Alberto Ricci

Michela D'Ascanio

and

Pier-Valerio Mari

submission deadline 31 Dec 2026 | 1 articles | Viewed by 2221 | Submission Open

Keywords: COPD; personalized therapy; treatable traits; biologic therapy; dupilumab; mepolizumab; type 2 inflammation; phenotyping; small airway disease; precision medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Laser Applications in Medicine: Current Status and Emerging Challenges

edited by Irit Juwiler

submission deadline 31 Dec 2026 | 1 articles | Viewed by 2163 | Submission Open

Keywords: lasers; medicine; surgery; dermatology; ophthalmology; dentistry; otolaryngology; gastroenterology; urology; gynecology; cardiology; neurosurgery; orthopedics; tissue types; biological interactions; technological advancements; clinical applications; health outcomes

(This special issue belongs to the Section Biomedical Engineering and Materials)

Tumor Immune Microenvironment, Metabolic Remodeling and Mechanism of Cancer Metastasis

edited by

Yuhui Tang

and

Shaoquan Zheng

submission deadline 31 Dec 2026 | 1 articles | Viewed by 2082 | Submission Open

Keywords: tumor immune microenvironment; metabolic remodeling; cancer metastasis; immune–metabolic crosstalk; novel therapeutic targets for metastasis

(This special issue belongs to the Section Cancer Biology and Oncology)

Emerging Challenges in Pediatric Disease Management: Current Trends and Future Perspectives

edited by

Lorenzo Di Sarno

and Antonio Chiaretti

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2048 | Submission Open

Keywords: pediatric diseases; pediatric infection; pediatric trauma management; acute respiratory failure; neurological emergencies; toxidromes and poisoning; point-of-care ultrasound (POCUS); novel biomarkers; therapeutic strategies

(This special issue belongs to the Section Molecular and Translational Medicine)

New Diagnostic and Therapeutic Approaches in Diabetic Microvascular Complications, 3rd Edition

edited by

Ana Maria Dascalu

and

Dragos Serban

submission deadline 31 Dec 2026 | 3 articles | Viewed by 1985 | Submission Open

Keywords: diabetic retinopathy; diabetic foot ulcer; inflammatory biomarkers; microbiota; novel therapies

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Pancreatitis: Aetiology, Pathology, and Treatment

edited by

Wenhao Cai

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1926 | Submission Open

Keywords: acute pancreatitis; chronic pancreatitis; inflammation; fibrosis; pathophysiology; therapeutics

(This special issue belongs to the Section Immunology and Immunotherapy)

Neurological Complications in Oncology: From Pathogenesis to Therapy

edited by Pierfranco Conte

submission deadline 31 Dec 2026 | 2 articles | Viewed by 1864 | Submission Open

Keywords: neurological complications; neuro-oncology; neurotoxicity; chemotherapy-induced cognitive impairment; cancer-related neuropathy; neuroprotection; neuroimaging

(This special issue belongs to the Section Cancer Biology and Oncology)

Cardiovascular Disease: From Bioengineering Tools to Pharmacological Therapies

edited by

Talal Almas

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1850 | Submission Open

Keywords: cardiogenic shock; heart failure; device therapeutics; mechanical circulatory support; cardiovascular prevention; hypertension; dyslipidemia

(This special issue belongs to the Section Biomedical Engineering and Materials)

Diabetic Nephropathy and Diabetic Atherosclerosis (2nd Edition)

edited by

Satyesh K. Sinha

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1846 | Submission Open

Keywords: diabetic nephropathy; diabetic atherosclerosis; diabetes; inflammation; oxidative stress; renal and vascular cell dysfunction; basic science; clinical practice; patient outcomes

(This special issue belongs to the Section Molecular and Translational Medicine)

Personalized Diagnosis and Therapy in Endocrinology and Gynecology

edited by

Sarah Allegra

submission deadline 31 Dec 2026 | 2 articles | Viewed by 1816 | Submission Open

Keywords: personalized medicine; endocrine disorders; gynecological diseases; reproductive endocrinology; pharmacogenomics; hormonal therapy; polycystic ovary syndrome (PCOS); precision medicine; biomarkers; women’s health

(This special issue belongs to the Section Molecular and Translational Medicine)

Roles of Extracellular Vesicles in Health and Diseases

edited by David R. Brigstock and Xinlei Li

submission deadline 31 Dec 2026 | 2 articles | Viewed by 1563 | Submission Open

Keywords: extracellular vesicle; exosome; pathogenesis; therapy; cancer; neurodegenerative diseases; pulmonary diseases; cardiovascular diseases; inflammatory diseases; infectious diseases; kidney diseases; gastrointestinal diseases; aging; diabetes; autoimmune disorders

(This special issue belongs to the Section Molecular and Translational Medicine)

Aging and Decoding Aging

edited by Bingrui Li, Xuanye Cao and Wen Jiang

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1548 | Submission Open

Keywords: aging; computational modeling; AI; healthspan and lifespan prediction; systems biology

(This special issue belongs to the Section Cell Biology and Pathology)

Urological Oncology: Advances in Precision Diagnosis and Targeted Therapies

edited by

Zhiyong Xiong

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1535 | Submission Open

Keywords: urological oncology; precision diagnosis; targeted therapy; tumor metabolism; biomarkers; multi-omics; personalized medicine; drug resistance; liquid biopsy; genomic profiling

(This special issue belongs to the Section Cancer Biology and Oncology)

Pathogenesis and Treatment of Amyotrophic Lateral Sclerosis (ALS)

edited by

Dongsheng Fan

submission deadline 31 Dec 2026 | 2 articles | Viewed by 1511 | Submission Open

Keywords: amyotrophic lateral sclerosis (ALS); multi-target therapy; drug repurposing; translational research; biomarkers; induced pluripotent stem cells (iPSCs); clinical trial design; AI-based prediction models; precise treatment

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Endocrine and Metabolic Insights in Chronic Kidney Disease: Mechanisms, Diagnosis, and Treatment

edited by Shu Rong

submission deadline 31 Dec 2026 | 2 articles | Viewed by 1468 | Submission Open

Keywords: chronic kidney disease; endocrine and metabolic disorders; kidney injury mechanism; diagnostic biomarker; precision diagnosis and treatment; clinical intervention; renal fibrosis; gut microbiota

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Neuro-Orthopaedics: Neural Injury, Pain, and Functional Recovery in Musculoskeletal Disorders

edited by

Wencai Liu

submission deadline 31 Dec 2026 | 2 articles | Viewed by 1450 | Submission Open

Keywords: neuro-orthopaedics ; spinal cord injury ; peripheral nerve injury ; musculoskeletal pain ; neuroinflammation ; neuroregeneration ; functional recovery ; spine surgery ; sports medicine

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Genome Engineering Technologies for Diseases

edited by Kosuke Ishikawa

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1432 | Submission Open

Keywords: genome engineering; gene editing; gene delivery; transposable elements; insertinal mutagenesis; functional genomics; in silico analysis; cell-based assays; disease modeling; cell therapy

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Advancements in Understanding and Treating Oral Pathologies: From Dry Mouth to Oral Cancer—2nd Edition

edited by Eleni Georgakopoulou and George Laskaris

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1396 | Submission Open

Keywords: oral pathologies; oral diseases; pathogenesis; therapeutic interventions; interdisciplinary nature of oral healthcare; xerostomia; dysgeusia; oral cancer; precancerous lesions; oral inflammatory conditions

(This special issue belongs to the Section Cell Biology and Pathology)

Emerging Trends and Applications in Nanomedicine and Targeted Therapies

edited by

Marzieh Ramezani Farani

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1377 | Submission Open

Keywords: nanomedicine; drug delivery systems; targeted therapy; biomaterials; cancer therapy; smart nanocarriers; biodegradable nanoparticles; photothermal therapy; nano-diagnostics; translational nanotechnology

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Emerging Insights into HIV: Second Edition

edited by

Konstantinos Protopapas

, Antonios Papadopoulos and

Charalampos D. Moschopoulos

submission deadline 31 Dec 2026 | 2 articles | Viewed by 1371 | Submission Open

Keywords: HIV/AIDS; antiretroviral treatment; comorbidities; co-infection; neuroHIV

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Arrhythmia: Mechanisms, Biomarkers, and Emerging Therapies

edited by

Larisa Anghel

, Radu Andy Sascau and

Cristian Stătescu

submission deadline 31 Dec 2026 | 2 articles | Viewed by 1360 | Submission Open

Keywords: arrhythmias; atrial fibrillation; ventricular arrhythmias; electrophysiology; biomarkers; cardiac imaging; myocardial strain; inflammation

(This special issue belongs to the Section Molecular and Translational Medicine)

Molecular Biomarkers in Inflammatory Bowel Disease: Pathophysiology and New Therapeutic Strategies—3rd Edition

edited by

Marino Vilović

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1217 | Submission Open

Keywords: inflammatory bowel disease (IBD); Crohn’s disease; ulcerative colitis; biomarkers; molecular biomarkers in IBD; pathophysiology; therapeutic approaches in IBD; precision medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Triple Negative Breast Cancer: From Mechanisms to Therapeutic Approaches (2nd Edition)

edited by Padmashree Rida and Emad Rakha

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1135 | Submission Open

Keywords: triple-negative breast cancer; neoadjuvant; adjuvant; chemotherapy; immunotherapy; antibody–drug conjugates; immune checkpoint inhibitors; DNA damage; EGFR; FGFR; microtubule dynamics; centrosome amplification

(This special issue belongs to the Section Molecular and Translational Medicine)

Artificial Intelligence and Multi-Omics Integration in Precision Therapy

edited by Run Shi, Yongjie Wang and Jingjiang Chou

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1129 | Submission Open

Keywords: artificial intelligence; multi-omics integration; precision therapy; machine learning; biomarker discovery; drug response prediction; translational bioinformatics; personalized medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Cancer Cell Metabolism and Tumor Microenvironment

edited by

Bo Li

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1090 | Submission Open

Keywords: metabolism; cancer; immune cells; tumor microenvironment; cancer-associated organ failure; cancer therapeutics

(This special issue belongs to the Section Endocrinology and Metabolism Research)

New Horizons in Enzyme Inhibitor Discovery: Targets, Design and Evaluation—2nd Edition

edited by Chenzhou Hao and Yin Sun

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1031 | Submission Open

Keywords: enzyme inhibitors; drug design; inhibitor screening; medicinal chemistry; targets validation; structure–activity relationship; structure–property relationship

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Glioblastoma: Novel Multitargeted Approaches

edited by

Wenjing Zeng

submission deadline 31 Dec 2026 | Viewed by 990 | Submission Open

Keywords: glioblastoma; multitargeted therapy; tumor heterogeneity; immunotherapy; targeted agents; nanomedicine; RNA therapeutics; combination therapy; translational oncology

Skin Cancer: From Molecular Mechanisms to Clinical Translation

edited by Banu Farabi and

Rahim Hirani

submission deadline 31 Dec 2026 | 1 articles | Viewed by 939 | Submission Open

Keywords: skin cancer; melanoma; keratinocyte carcinoma; cancer biology; translational dermatology; skin imaging; artificial intelligence; precision medicine

(This special issue belongs to the Section Cancer Biology and Oncology)

Antioxidants in Treating Obesity and Metabolic Diseases

edited by Bee Ling Tan

submission deadline 31 Dec 2026 | 2 articles | Viewed by 896 | Submission Open

Keywords: antioxidant; dyslipidemia; flavonoid; heart disease; hypertension; insulin resistance; obesity; polyphenol; stroke; type 2 diabetes

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Advances in Hepatology (2nd Edition)

edited by Yuanwen Chen

submission deadline 31 Dec 2026 | 1 articles | Viewed by 893 | Submission Open

Keywords: metabolic dysfunction-associated steatotic liver disease (MASLD); metabolic dysfunction-associated steatohepatitis (MASH); alcohol-associated liver disease (ALD); alcohol-associated hepatitis; viral hepatitis; liver cancer; autoimmune liver diseases; liver fibrosis; gut microbiota; neuroimmune; inflammatory mechanisms; oxidative stress; reversibly oxidized human non-mercaptalbumin-1; irreversibly oxidized human non-mercaptalbumin-2 (HNA2)

(This special issue belongs to the Section Molecular and Translational Medicine)

Rheumatic Diseases: From Pathophysiology to Current and Emerging Therapeutic Approaches

edited by Harriet Morf

submission deadline 31 Dec 2026 | 1 articles | Viewed by 813 | Submission Open

Keywords: rheumatic diseases; molecular mechanisms; treatment; artificial intelligence; cytokine; anti-rheumatic drugs

(This special issue belongs to the Section Immunology and Immunotherapy)

Biomarkers in Solid Tumors: Recent Advances and Challenges

edited by

Raghu Sinha

submission deadline 31 Dec 2026 | 1 articles | Viewed by 776 | Submission Open

Keywords: biomarkers; liquid biopsy; diagnosis; prognosis; cancer; multi-omics; next-generation sequencing

(This special issue belongs to the Section Cancer Biology and Oncology)

Gene- and Peptide-Based Therapeutics for Neurodegenerative Disorders

edited by

Ramona Meanti

and Chiara Lucchi

submission deadline 31 Dec 2026 | Viewed by 729 | Submission Open

Keywords: neurodegenerative diseases; gene therapy; peptide-based therapeutics; targeted drug delivery; neuroprotection

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Molecular Insights and Advances in Metabolic Disorders

edited by Zhelong Liu and Ling Gao

submission deadline 31 Dec 2026 | 1 articles | Viewed by 698 | Submission Open

Keywords: metabolic disorders; type 2 diabetes; obesity; molecular mechanism; gut microbiota; biomarkers; mitochondrial dysfunction; therapeutic targets

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Role of MicroRNA in Tumor

edited by

Dariusz Jarych

and

Izabela Zawlik

submission deadline 31 Dec 2026 | 1 articles | Viewed by 685 | Submission Open

Keywords: microRNA (miRNA); oncomiRs; cancer biomarkers; liquid biopsy; extracellular vesicles; tumor microenvironment; cancer stem cells; miRNA therapeutics; chemoresistance; non-coding RNA; gene regulation; RNA-based therapeutics; multi-omics

(This special issue belongs to the Section Cancer Biology and Oncology)

Lung Cancer: Advances in Diagnosis and Treatment

edited by Hatim E. Sabaawy

submission deadline 31 Dec 2026 | 1 articles | Viewed by 636 | Submission Open

Keywords: lung cancer; precision diagnostics; multiomics; organoids; humanized models; combination therapy; precision medicine; personalized therapy

(This special issue belongs to the Section Cancer Biology and Oncology)

Hepatic Carcinoma: New Advances in Pathogenesis, Diagnosis and Therapy

edited by

Jincheng Wang

and

Wenchao Gu

submission deadline 31 Dec 2026 | 1 articles | Viewed by 613 | Submission Open

Keywords: epigenetic regulation; metabolic reprogramming; liquid biopsy; drug resistance mechanisms; locoregional therapy; gut-liver axis; artificial intelligence in oncology; non-invasive diagnosis

(This special issue belongs to the Section Cancer Biology and Oncology)

Targeting Mast Cells in Human Disease: Bridging Pathology and Therapy

edited by Marianna Criscuolo

submission deadline 31 Dec 2026 | Viewed by 553 | Submission Open

Keywords: mast cell; mast cell activation syndrome; anaphylaxis; mastocytosis; anti-mediator therapy

(This special issue belongs to the Section Immunology and Immunotherapy)

Optogenetic Tools for Probing Biology

edited by

Qunxiang Ong

submission deadline 31 Dec 2026 | Viewed by 548 | Submission Open

Keywords: optogenetics; signaling transduction; neuroscience; immunology; cancer signaling; synthetic biology; spatiotemporal resolution

(This special issue belongs to the Section Molecular and Translational Medicine)

Neuroinflammation and Brain Clearance Systems: Therapeutic Frontiers in Neurodegenerative Diseases

edited by

Che Mohd Nassir

and

Angelo Antonini

submission deadline 31 Dec 2026 | 1 articles | Viewed by 514 | Submission Open

Keywords: neuroinflammation; glymphatic system; neurodegeneration; blood–brain barrier; neurovascular unit; microglia; astrocytes; protein aggregation; neuroprotection; phytochemicals; medicinal plants

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Anticancer Agents: Synthesis and Evaluation of Pharmacological Activities

edited by

Quanjun Yang

submission deadline 31 Dec 2026 | 1 articles | Viewed by 469 | Submission Open

Keywords: anticancer agents; drug synthesis; pharmacological evaluation; medicinal chemistry; targeted therapy; drug delivery; chemoresistance; natural products

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Extracellular Vesicles in Biomedicines

edited by Chen Zhao and You-Ren Ji

submission deadline 31 Dec 2026 | Viewed by 449 | Submission Open

Keywords: extracellular vesicles (EVs); liquid biopsy; circulating biomarkers; exosome; nanomedicine; translational oncology; precision medicine

(This special issue belongs to the Section Cell Biology and Pathology)

Gastrointestinal Diseases: From Pathophysiology to Therapeutics

edited by Ali H. Zaidi and Neda Dadgar

submission deadline 31 Dec 2026 | Viewed by 399 | Submission Open

Keywords: gastrointestinal diseases; pathophysiology; gastrointestinal cancer; esophageal cancer; gastric cancer; colorectal cancer; pancreatic cancer; hepatocellular cancer; appendiceal cancer; cancer biomarker

(This special issue belongs to the Section Molecular and Translational Medicine)

New Advances in the Treatment of Brain Tumors

edited by

Harim Koo

submission deadline 31 Dec 2026 | Viewed by 392 | Submission Open

Keywords: neuro-oncology; brain tumor; cancer therapy; precision medicine; biomarkers; drug delivery; multi-omics; neurosurgery; clinical trials; bioinformatics

(This special issue belongs to the Section Cancer Biology and Oncology)

Advances in Atherosclerosis and Associated Diseases: From Molecular Mechanisms to Personalized Therapeutic Approaches

edited by

Patricia Pia Wadowski

and

Henriette Löffler-Stastka

submission deadline 31 Dec 2026 | Viewed by 391 | Submission Open

Keywords: atherosclerosis; coronary artery disease; stroke; neuroinflammation; vascular inflammation; cardiovascular disease; cardiovascular biomarkers; novel therapeutic strategies; precision medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Innovative Drug Target Discovery in Cancer: From Molecular Mechanisms to Therapeutic Targets

edited by Rakesh Nair

submission deadline 31 Dec 2026 | Viewed by 356 | Submission Open

Keywords: cancer therapy; drug target; drug resistance; oncology drug development; cancer metastasis mechanisms; signaling pathways; biomarker

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

New Insights into the Tumor Microenvironment: Mechanisms and Therapeutic Strategies

edited by

Denggang Fu

submission deadline 31 Dec 2026 | Viewed by 350 | Submission Open

Keywords: tumor microenvironment (TME); immune evasion; tumor–immune interaction; stromal remodeling; cancer immunotherapy; metabolic reprogramming; epigenetic regulation; multi-omics and spatial analysis; anticancer drug development

(This special issue belongs to the Section Immunology and Immunotherapy)

Displaying special issue 201-250 on page 5 of 14.

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