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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Skin Diseases: From Molecular Mechanisms to Novel Therapeutic Approaches

edited by

Guangtong Deng

submission deadline 30 Nov 2025 | 4 articles | Viewed by 3360 | Submission Open

Keywords: skin diseases; cell death; ferroptosis; cuproptosis; melanoma; cancer immunotherapy; psoriasis

(This special issue belongs to the Section Molecular and Translational Medicine)

Advanced Research in Pulmonary Pathophysiology

edited by Ourania S. Kotsiou and Erasmia Rouka

submission deadline 30 Nov 2025 | 1 articles | Viewed by 3187 | Submission Open

Keywords: pathophysiology; aging; disease; injury; microbiome; small airways; pleura; lung cancer; infections; critical care

(This special issue belongs to the Section Cell Biology and Pathology)

Exploring Human Diseases Through Genomic and Genetic Analyses

edited by Fernando Regateiro and

Henriqueta Silva

submission deadline 30 Nov 2025 | 3 articles | Viewed by 2964 | Submission Open

Keywords: genomic and genetic analyses; genomic medicine; personalized medicine; technologies and testing methods; complex diseases; monogenic diseases; pharmacogenomics

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Advances in Reproductive Endocrinology and Fertility: From Bench to Bedside

edited by

Myung Joo Kim

submission deadline 30 Nov 2025 | 1 articles | Viewed by 2916 | Submission Open

Keywords: reproductive health; reproductive system diseases; hormonal regulation; infertility; reproductive dysfunction; reproductive genetics; reproductive physiology; assisted reproductive technologies

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Genomics and Bioinformatics of Human Disease

edited by Sankarasubramanian Jagadesan

submission deadline 30 Nov 2025 | 2 articles | Viewed by 2713 | Submission Open

Keywords: genomics; bioinformatics; precision medicine; single-cell RNA sequencing; genetic variations; cellular heterogeneity; AI/ML; pathogenicity prediction

(This special issue belongs to the Section Molecular and Translational Medicine)

The Role of Iron in Human Diseases

edited by Margherita Correnti

submission deadline 30 Nov 2025 | 3 articles | Viewed by 2646 | Submission Open

Keywords: iron metabolism; iron dysregulation; diseases; iron deficiency; iron overload

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Neurodegeneration No More: Cutting-Edge Technologies and Therapies in the Evolution of Neurodegenerative Disease Management—2nd Edition

edited by

Masaru Tanaka

Simone Battaglia

and

Donato Liloia

submission deadline 30 Nov 2025 | 2 articles | Viewed by 2496 | Submission Open

Keywords: Alzheimer’ s disease; frontotemporal lobar degeneration; Parkinson’ s disease; aging decline; mild cognitive impairment; multiple sclerosis; stroke; acquired brain damage; altered cognitive processes; brain functional impairment; neurocognitive disorders; cognitive; behavioral; and functional disorders; acquired trauma; brain plasticity and connectivity; non-invasive brain stimulation; diagnosis and treatment; functional evidence of altered cognition and connectivity; blood-based biomarkers; disease heterogeneity; prognosis; protein aggregation; inflammation; oxidative stress; medicinal plants; phytocompounds

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Role of Natural Product in Cardiovascular Disease—2nd Edition

edited by

Jian Li

submission deadline 30 Nov 2025 | 2 articles | Viewed by 2451 | Submission Open

Keywords: nature products; phytochemicals; biological and pharmacological activity; cardiovascular disease (CVD) pathogenesis of CVD; risk factors of CVD; metabolic symptom; clinical or preclinical studies

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Connections Between Diabetes Mellitus, Other Metabolic and Endocrine Dysfunctions and Cardiovascular Pathologies—Second Edition

edited by

Cristina Tudoran

and Dragos Cozma

submission deadline 30 Nov 2025 | 4 articles | Viewed by 2279 | Submission Open

Keywords: diabetes mellitus; insulin resistance; metabolic syndrome; obesity; thyroid dysfunction; hormonal alterations; endothelial dysfunction; coronary artery disease; hypertension; peripheric arterial disease

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Animal Models for Neurological Disease Research

edited by

Sreeja Sarasamma

submission deadline 30 Nov 2025 | 2 articles | Viewed by 2167 | Submission Open

Keywords: animal models; neurological diseases; genetic models; CRISPR/Cas9; transgenic organisms; behavioral analysis; neurodegeneration; single-cell approaches; zebrafish; lamprey; biocomputational approaches; gene therapy; pharmacological interventions; translational neurobiology; disease pathways

(This special issue belongs to the Section Molecular and Translational Medicine)

Periodontal Disease and Periodontal Tissue Regeneration—Second Edition

edited by

Irina-Georgeta Sufaru

and

Sorina Mihaela Solomon

submission deadline 30 Nov 2025 | 1 articles | Viewed by 2152 | Submission Open

Keywords: periodontal diagnosis; periodontal immunology; periodontal microbiology; periodontal tissue regeneration; tissue engineering

(This special issue belongs to the Section Biomedical Engineering and Materials)

Thoracic Malignancies: From Pathophysiology to Novel Therapeutic Approaches

edited by Yanyun Gao

submission deadline 30 Nov 2025 | 3 articles | Viewed by 1977 | Submission Open

Keywords: thoracic malignancies; lung cancer; esophageal cancer; pleural mesothelioma (PM); molecular subtypes; drug resistance; target therapy; biomarkers; immunotherapy; preclinical models

(This special issue belongs to the Section Cancer Biology and Oncology)

Advances in the Pathogenesis and Treatment of Heart Failure and Cardiomyopathy

edited by

Andrey Jorge Serra

, Ednei Luiz Antonio, Gianna Móes de Albuquerque-Pontes and Luis Felipe Neves dos Santos

submission deadline 30 Nov 2025 | 3 articles | Viewed by 1923 | Submission Open

Keywords: cardiomyopathy; cardiac remodeling; heart disease; heart failure; mechanisms; new therapies; targeted therapies

(This special issue belongs to the Section Molecular and Translational Medicine)

Coronary Artery Disease: From Pathophysiology to Therapeutic Strategies

edited by

Pawel Nadziakiewicz

submission deadline 30 Nov 2025 | 2 articles | Viewed by 1834 | Submission Open

Keywords: pathophysiological concept of coronary artery disease; coronary microvascular dysfunction; chronic coronary syndrome; acute coronary syndrome; post-acute coronary syndrome with heart failure; diagnostics in coronary artery disease; therapeutic strategies in CAD; revascularization

(This special issue belongs to the Section Cell Biology and Pathology)

Advances in Brain Tumor Diagnosis: Innovations and Emerging Technologies

edited by

Mubarak Taiwo Mustapha

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1773 | Submission Open

Keywords: brain tumor diagnosis; artificial intelligence in oncology; deep learning in medical imaging; machine learning models; predictive analytics in healthcare; digital pathology; glioma detection; multi-modal data integration; neuro-oncology; precision medicine

(This special issue belongs to the Section Cancer Biology and Oncology)

Molecular Research of Neurological and Psychiatric Disorders

edited by

Yuen Gao

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1686 | Submission Open

Keywords: molecular biology; neurodegenerative disorders; psychiatry; biomarkers; therapeutic targets

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Biomarkers for Neurodegenerative Disorders: From Bench to Bedside

edited by George P. Paraskevas

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1673 | Submission Open

Keywords: dementia; Alzheimer’ s disease; frontotemporal dementia; dementia with Lewy bodies; parkinsonism; tau protein; TDP-43; α -synuclein; Tau-PET; amyloid-PET

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Inflammatory Bowel Diseases: New Diagnostic and Therapeutic Approaches—Second Edition

edited by

Maria Manuela Estevinho

and

Fernando Magro

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1491 | Submission Open

Keywords: bowel inflammation; Crohn’ s disease; endoscopy; inflammatory bowel disease; targeted therapy; ulcerative colitis

(This special issue belongs to the Section Immunology and Immunotherapy)

New Insights in Radiotherapy: Bridging Radiobiology and Oncology

edited by

Yuan-Hao Lee

and I-Tsang Chiang

submission deadline 30 Nov 2025 | 2 articles | Viewed by 1383 | Submission Open

Keywords: tissue-sparing effect; bystander effect; factors that affect radiation-induced lethality; radiation-induced abscopal effect; mechanisms that enhance tissue radiosensitivity; synergistic effect from radiotherapy and immunotherapy; regulatory perspectives on medical radiation safety

(This special issue belongs to the Section Cancer Biology and Oncology)

Pediatric Tumors: Diagnosis, Pathogenesis, Treatment, and Outcome

edited by Hermann L. Müller

submission deadline 30 Nov 2025 | 3 articles | Viewed by 1316 | Submission Open

Keywords: pediatric oncology; leukemia; sarcoma; brain tumor; chemotherapy; irradiation; targeted therapy; sequelae

(This special issue belongs to the Section Cancer Biology and Oncology)

Neurodevelopmental and Neuropsychiatric Disorders in Animal Models

edited by Yael Abreu-Villaça

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1213 | Submission Open

Keywords: mood disorder; mental disorder; substance use disorder; autism spectrum disorder (ASD); attention-deficit/hyperactive disorder (ADHD); depression and anxiety disorders; schizophrenia; bipolar disorder; epilepsy; eating disorders

(This special issue belongs to the Section Molecular and Translational Medicine)

Two Decades of Advances in Colorectal Cancer Prevention and Treatment: From Aspirin to Precision Oncology

edited by

Manish Tripathi

and

Puneet Vij

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1204 | Submission Open

Keywords: immunotherapy; biomarkers; colorectal cancer; targeted therapies; molecular pathways

(This special issue belongs to the Section Cancer Biology and Oncology)

State-of-the-Art Endocrine Cancer Biology and Oncology

edited by

Piotr Glinicki

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1036 | Submission Open

Keywords: thyroid and parathyroid tumors; adrenal tumors (hormonally active and inactive; ACC); neuroendocrine tumors (NEN); pituitary neuroendocrine tumors (PiNETs)

(This special issue belongs to the Section Cancer Biology and Oncology)

Non-Invasive Brain Stimulation Techniques and Their Application in the Study of Cognitive Function Physiology and Neuro-Psychiatric Rehabilitation

edited by

Mattia Ferro

Jacopo Lamanna

and Andrea Stefano Moro

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1018 | Submission Open

Keywords: non-invasive brain stimulation; neurophysiology; cognitive function; depression; schizophrenia

(This special issue belongs to the Section Molecular and Translational Medicine)

Innovative Biomaterials and Advanced Techniques for Bone Regeneration Applications

edited by

Antonio Apicella

submission deadline 30 Nov 2025 | 1 articles | Viewed by 904 | Submission Open

Keywords: biomaterials; bone regeneration; osteointegration; 3D printing; biomimetic design

(This special issue belongs to the Section Biomedical Engineering and Materials)

Phenotypes and Endotypes in Interstitial Lung Diseases—Second Edition

edited by

Francesco Amati

submission deadline 30 Nov 2025 | 1 articles | Viewed by 588 | Submission Open

Keywords: interstitial lung diseases (ILDs); heterogeneity; pathogenesis; progressive pulmonary fibrosis (PPF); molecular biomarkers

(This special issue belongs to the Section Immunology and Immunotherapy)

Cardiomyopathies and Heart Failure: Charting the Future—2nd Edition

edited by Ali Amr

submission deadline 30 Nov 2025 | 1 articles | Viewed by 408 | Submission Open

Keywords: cardiomyopathies; heart failure; risk stratification; management of cardiomyopathies; cardiac imaging; telemedicine

(This special issue belongs to the Section Cell Biology and Pathology)

The Interplay Between miRNA and Mitochondrial Dysfunction in Neurodegenerative Diseases

edited by

Mariano Catanesi

submission deadline 30 Nov 2025 | Viewed by 356 | Submission Open

Keywords: miRNA; neurodegenerative diseases; mitochondrial dysfunction; aging; gene expression

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Molecular Mechanisms of Normal and Malignant Hematopoiesis: 2nd Edition

edited by

Myunggon Ko

submission deadline 30 Nov 2025 | Viewed by 340 | Submission Open

Keywords: hematopoietic stem cells; self-renewal; differentiation; hematological malignancies; molecular mechanisms; genetic factors; epigenetic factors; transcriptional regulation; HSC niche; targeted therapy

(This special issue belongs to the Section Molecular and Translational Medicine)

Feature Reviews in Cancer Genetics and Epigenetics

edited by

Zheng-Yuan Su

submission deadline 30 Nov 2025 | Viewed by 265 | Submission Open

Keywords: cancer genetics; epigenetics; DNA methylation; histone modifications; non-coding RNAs; tumor heterogeneity; drug resistance; biomarkers; precision oncology; personalized therapy

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Diagnosis, Management and Treatment of Rheumatoid Arthritis

edited by Yong Feng

submission deadline 30 Nov 2025 | Viewed by 227 | Submission Open

Keywords: rheumatoid arthritis; autoimmune disorder; synovial inflammation; genetic factors; signaling pathway; targeted therapies

(This special issue belongs to the Section Molecular and Translational Medicine)

Molecular and Histopathological Background of Diabetic Neuropathy

edited by

Mária Bagyánszki

submission deadline 30 Nov 2025 | Viewed by 213 | Submission Open

Keywords: diabetic neuropathy; insulin; hyperglycaemia; peripheral neuropathy; autonomic neuropathy; proximal neuropathy; enteric neuropathy; mononeuropathy

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

The Role of HOX Genes in Particular Cancers

edited by

Renata Freitas

submission deadline 30 Nov 2025 | Viewed by 213 | Submission Open

Keywords: HOX genes; anti-cancer drugs; cell memory program; epigenetic regulation

(This special issue belongs to the Section Cancer Biology and Oncology)

Advances in Molecular Research on Physical Activity, Sleep and Cognitive Function

edited by

Yanwei You

submission deadline 30 Nov 2025 | Viewed by 209 | Submission Open

Keywords: physical activity; sleep; cognitive function; molecular mechanisms; neuroplasticity; oxidative stress; inflammation; biomarkers

(This special issue belongs to the Section Molecular and Translational Medicine)

Hepatocellular Carcinoma: From Pathophysiology to Therapeutic Approaches Treatment

edited by

Wasim A. Dar

submission deadline 30 Nov 2025 | Viewed by 209 | Submission Open

Keywords: hepatocellular carcinoma; pathophysiology; therapeutic interventions

(This special issue belongs to the Section Cancer Biology and Oncology)

Exercise-Induced Physiological Responses: From Oxidative Stress to DNA Alterations

edited by

Robert Stawski

submission deadline 30 Nov 2025 | Viewed by 194 | Submission Open

Keywords: exercise-induced oxidative stress; reactive oxygen species (ROS); molecular adaptations to exercise; epigenetic modifications in exercise; DNA damage and repair; cell-free DNA; extracellular DNA; inflammation and exercise; DNA alterations

(This special issue belongs to the Section Cell Biology and Pathology)

Animal Models of Human Pathology: Revision, Relevance and Refinements (4th Edition)

edited by

Martina Perše

submission deadline 30 Nov 2025 | Viewed by 193 | Submission Open

Keywords: animal models; biomarkers; human disease; pathology; translation; mechanisms; nephrology; gastroenterology; urology; neuroscience; cancer; experimental design; reproducibility; refinements

(This special issue belongs to the Section Molecular and Translational Medicine)

Therapeutic Resistance in Oral Cancer: Mechanisms, Biomarkers, and Novel Strategies to Restore Treatment Responses

edited by

Vui King Vincent-Chong

submission deadline 30 Nov 2025 | Viewed by 193 | Submission Open

Keywords: oral cancer; OSCC; chemotherapy; radiotherapy; immunotherapy; therapeutic resistance; HNSCC; biomarker; tumor microenvironment

(This special issue belongs to the Section Cancer Biology and Oncology)

Recent Advances in Lymphoma: Second Edition

edited by

Socorro María Rodríguez-Pinilla

and

Marta Rodríguez Moreno

submission deadline 30 Nov 2025 | Viewed by 188 | Submission Open

Keywords: lymphoma; cancer; gene expression; mutational analysis; target; therapy; tumor microenvironment

(This special issue belongs to the Section Cancer Biology and Oncology)

Application of New Technologies in Drug Delivery

edited by Venkata Raman Kallakunta

submission deadline 30 Nov 2025 | Viewed by 174 | Submission Open

Keywords: drug delivery; new technologies; nanoparticles; self-emulsifying drug delivery systems (SEDDSs); hot melt extrusion (HME); gene editing; 3D printing

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Urogenital Cancers: New Molecular and Translational Aspects on Carcinogenesis and Treatments (2nd Edition)

edited by

Silvia Di Agostino

Vittoria Rago

and

Anna Perri

submission deadline 30 Nov 2025 | Viewed by 171 | Submission Open

Keywords: prostate cancer; bladder cancer; renal cell carcinoma; testicular cancer; ovarian cancer; endometrial cancer; carcinogenesis; biomarkers; early diagnosis; upper urinary tract tumors; diagnosis; treatment; environmental factors; diet

(This special issue belongs to the Section Cancer Biology and Oncology)

Mitochondrion-Targeting Agents for Tumor Therapy

edited by

Menghuan Tang

submission deadline 30 Nov 2025 | Viewed by 169 | Submission Open

Keywords: mitochondria; cell signaling; apoptosis; cancer therapy

(This special issue belongs to the Section Cancer Biology and Oncology)

Advances of Microbiome in Human Cancers

edited by

Weg M. Ongkeko

submission deadline 30 Nov 2025 | Viewed by 165 | Submission Open

Keywords: human microbiome; gut microbiota; tumor-resident microbes; translational research; biomarkers; computational biology

(This special issue belongs to the Section Cancer Biology and Oncology)

Pathogenesis, Diagnosis, and Treatment of Prostate Cancer

edited by

Sara Harsini

submission deadline 30 Nov 2025 | Viewed by 142 | Submission Open

Keywords: prostate cancer ; molecular imaging; PET/CT; PSMA (prostate-specific membrane antigen); theranostics; radiopharmaceutical therapy; diagnosis and staging; radiology; targeted therapy; tumor microenvironment

(This special issue belongs to the Section Molecular and Translational Medicine)

Decoding Colorectal Cancer: Innovations in Biomarkers, Microbiota, and Therapeutic Resistance

edited by

Yinghao Cao

submission deadline 30 Nov 2025 | Viewed by 141 | Submission Open

Keywords: colorectal cancer; tumor biomarkers; nanomaterials; drug delivery; microbiome– tumor interaction; therapeutic resistance; exosomes; tumor microenvironment; prognostic model; neoadjuvant therapy; conversion therapy

(This special issue belongs to the Section Cancer Biology and Oncology)

Advances in the Pathogenesis and Treatment of Acute Myeloid Leukemia—2nd Edition

edited by

Alessandra Sperotto

submission deadline 30 Nov 2025 | Viewed by 139 | Submission Open

Keywords: acute myeloid leukemia; target therapies; molecular pathogenesis; biological therapy; precision medicine

(This special issue belongs to the Section Cancer Biology and Oncology)

Novel Biomaterials and Tissue Engineering Approaches in Periodontal Regeneration

edited by

Federico Mussano

submission deadline 30 Nov 2025 | Viewed by 139 | Submission Open

Keywords: periodontium; tissue engineering; regenerative medicine; biomaterials; bioprinting; mesenchymal stem/stromal cells; senescence; aging; advanced therapeutics

(This special issue belongs to the Section Biomedical Engineering and Materials)

Coronary Artery Disease: Current Evidence and Future Perspectives

edited by Tadateru Takayama

submission deadline 30 Nov 2025 | Viewed by 136 | Submission Open

Keywords: coronary artery disease; lipid-lowering therapy; residual risk; small dense LDL; lipoprotein(a); endothelial dysfunction; oxidative stress; inflammation; biomarkers; cardiovascular prevention

(This special issue belongs to the Section Molecular and Translational Medicine)

Clinical Advances in Hepatocellular Carcinoma

edited by Mohamed A. Abd El Aziz

submission deadline 30 Nov 2025 | Viewed by 128 | Submission Open

Keywords: hepatocellular cancer; liver cirrhosis; chemotherapy; immunotherapy; radiofrequency ablation; microwave ablation

(This special issue belongs to the Section Cancer Biology and Oncology)

Advances in Neurophysiology and the Treatment of Parkinson’s Disease

edited by

Giorgia Sciacca

submission deadline 30 Nov 2025 | Viewed by 121 | Submission Open

Keywords: movement disorders; hypokinetic movement disorders; Parkinson’ s disease; levodopa; treatment; neurophysiology; neuroplasticity; motor learning

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Displaying special issue 201-250 on page 5 of 16.

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