Special Issues

Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advanced Research in Thyroid and Parathyroid Diseases
edited by Anping Su
submission deadline 30 Sep 2025 | 2 articles | Viewed by 1078 | Submission Open
Keywords: thyroid cancer treatment; tumor microenvironment; immunotherapy; targeted therapy; precision medicine
(This special issue belongs to the Section Cancer Biology and Oncology)
Impacts of Exercise, Nutrition, Obesity, Metabolism and Ageing on Regenerative Medicine and Their Applications in Tissue Engineering and Therapeutics
edited by
submission deadline 30 Sep 2025 | 2 articles | Viewed by 908 | Submission Open
Keywords: obesity; exercise; nutrition (diet); obesity; metabolism; ageing; regenerative medicine; tissue engineering; therapeutics
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Advances in Therapeutic Strategies and Precision Medicine in Solid Tumors and Metastasis—2nd Edition submission deadline 30 Sep 2025 | 1 articles | Viewed by 849 | Submission Open
Keywords: kinase inhibitor; immunotherapy; chemotherapy; precision molecular therapy; biomarkers; synthetic lethality; theranostics; drug repurposing; radiomics
(This special issue belongs to the Section Cancer Biology and Oncology)
Inherited Retinal Diseases: From Pathomolecular Mechanisms to Therapeutic Strategies, 2nd Edition submission deadline 30 Sep 2025 | 1 articles | Viewed by 846 | Submission Open
Keywords: blindness; gene and protein function; pathogenesis; personalized diagnosis; precision therapy; retina; retinal degeneration
(This special issue belongs to the Section Molecular and Translational Medicine)
Recent Research on Dry Eye
edited by Liat Gantz
submission deadline 30 Sep 2025 | 1 articles | Viewed by 836 | Submission Open
Keywords: dry eye; meibomian gland dysfunction; ocular surface disease
(This special issue belongs to the Section Molecular and Translational Medicine)
Stem Cell Therapy: Traps and Tricks
edited by and Željka Večerić-Haler
submission deadline 30 Sep 2025 | 1 articles | Viewed by 685 | Submission Open
Keywords: mesenchymal stem cells; MSC therapy; preclinical research; regenerative medicine
(This special issue belongs to the Section Biomedical Engineering and Materials)
Molecular and Cellular Research in Diabetes and Metabolic Diseases
edited by Miwon Ahn
submission deadline 30 Sep 2025 | 1 articles | Viewed by 626 | Submission Open
Keywords: insulin exocytosis; pre-diabetes; type 2 diabetes; organ cross-talk; diabetes drugs; diabetes clinical study; glucose homeostasis
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Biomedical Devices—Applications for Disease Treatment and Tissue Regeneration
edited by Eleni Papachristou
submission deadline 30 Sep 2025 | 1 articles | Viewed by 604 | Submission Open
Keywords: biomedical devices; mesenchymal stem cell; biomedical applications; Tissue engineering
(This special issue belongs to the Section Biomedical Engineering and Materials)
Integrative and Preventive Biomarkers for Cardiometabolic Diseases
edited by Tandi E. Matsha and
submission deadline 30 Sep 2025 | Viewed by 595 | Submission Open
Keywords: metabolic health; diabetes; cardiovascular disease; obesity; biomarkers; inflammation; endocrine; integrative medicine; epigenetics
(This special issue belongs to the Section Molecular and Translational Medicine)
Innovative Approaches in Drug Discovery
edited by Jitendra Gour
submission deadline 30 Sep 2025 | Viewed by 555 | Submission Open
Keywords: PROTACs; molecular glue; personalized medicine; high-throughput screening (HTS); targeted therapy; drug repurposing; safety profiles
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Advanced Molecular Mechanisms and Treatment of Neurological Diseases
edited by and Yanbo Yang
submission deadline 30 Sep 2025 | 1 articles | Viewed by 547 | Submission Open
Keywords: neurological disease; molecular mechanisms; neuroinflammation; metabolism; biomarkers; neuroprotection; gene therapy; omics; drug discovery; personalized medicine
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Advances in Stroke Neuroprotection and Repair submission deadline 30 Sep 2025 | 1 articles | Viewed by 526 | Submission Open
Keywords: stroke; cerebral infarction; neuronal damage; neural regeneration; neuroprotection
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Drug-Resistant Bacterial Infections and Alternative Therapies—2nd Edition
edited by
submission deadline 30 Sep 2025 | 1 articles | Viewed by 519 | Submission Open
Keywords: alternative agents; antibiotics; phages; endolysins; phytochemicals; drug discovery; nanoparticles; biofilms
(This special issue belongs to the Section Microbiology in Human Health and Disease)
Medical Imaging in Brain Tumor: Charting the Future submission deadline 30 Sep 2025 | Viewed by 498 | Submission Open
Keywords: brain tumor diagnosis; artificial intelligence (AI) in medical imaging; imaging biomarkers for brain tumor; detection; segmentation and classification; radiomics and radiogenomics; precision oncology; deep learning and machine learning; neuro oncology; digital pathology; treatment response monitoring
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Oral Cancer: From Pathophysiology to Novel Therapeutic Approach
edited by
submission deadline 30 Sep 2025 | 1 articles | Viewed by 490 | Submission Open
Keywords: oral cancer and pathophysiology; molecular mechanisms; biomarkers; immunological and targeted therapy; precision medicine and personalized therapies
(This special issue belongs to the Section Molecular and Translational Medicine)
Epigenetic Regulation of Kidney Development
edited by Hongbing Liu
submission deadline 30 Sep 2025 | 1 articles | Viewed by 427 | Submission Open
Keywords: epigenetic regulation; kidney development; gene expression patterns; targeted therapeutic strategies; epigenetic regulation of kidney development
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
New Advances in Ovarian Cancer
edited by
submission deadline 30 Sep 2025 | Viewed by 417 | Submission Open
Keywords: ovarian cancer; biomarkers; cell biology; gene regulation; target therapy; therapeutic resistance; precision medicine
(This special issue belongs to the Section Cancer Biology and Oncology)
Advanced Research on the Role of Biogenic Amines in Physiological and Pathological Conditions submission deadline 30 Sep 2025 | Viewed by 379 | Submission Open
Keywords: biogenic amines; memory; synapse; depression; anxiety; schizophrenia; glioma and neurodegenerative diseases
(This special issue belongs to the Section Molecular and Translational Medicine)
Eosinophil: Current Status and Future Perspectives
edited by
submission deadline 30 Sep 2025 | Viewed by 364 | Submission Open
Keywords: eosinophils; predictive biomarker; severe asthma; blood cell count; anti-eosinophils; mortality
(This special issue belongs to the Section Cell Biology and Pathology)
Hearing Loss: Mechanisms and Targeted Interventions
edited by Pavlidis Pavlos
submission deadline 30 Sep 2025 | Viewed by 357 | Submission Open
Keywords: hearing loss; syndromes; anatomy and physiology of the ear; implants; cochlear implantation; diseases of the middle ear; rehabilitation
(This special issue belongs to the Section Cell Biology and Pathology)
Innovations and Prospects in Single Cell RNA-seq for Biomedical Research
edited by
submission deadline 30 Sep 2025 | Viewed by 346 | Submission Open
Keywords: bioinformatics; cellular heterogeneity; methodology; molecular biology; single-cell RNA sequencing; single-nucleus RNA sequencing; tissue heterogeneity; transcriptomics
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
Diagnostic and Therapeutic Challenges of CAR-T Cell Therapy
edited by Vincenzo Maria Perriello
submission deadline 30 Sep 2025 | Viewed by 324 | Submission Open
Keywords: CAR-T therapy; immunotherapy; relapsed/refractory diffuse large B cell lymphoma (r/r DLBCL); relapsed/refractory mantle cell lymphoma (r/r MCL); B-acute lymphoblastic leukemia (r/r B-ALL); bridging therapy; cytokine release syndrome (CRS); immune effector cell associated neurotoxicity (ICANS); biomarkers; PET/CT assessment after CAR-T cell therapy
(This special issue belongs to the Section Gene and Cell Therapy)
The Role of the Myofibroblast in Fibrosis and Cancer
edited by Bingrui Li, Xuebin Fu, Xiaodong Zou and Xue Wan
submission deadline 30 Sep 2025 | Viewed by 323 | Submission Open
Keywords: fibroblasts and myofibroblasts; fibrosis (organ and tissue fibrosis); cancer; tissue injury; extracellular matrix
(This special issue belongs to the Section Molecular and Translational Medicine)
New Advances in Neuropharmacology
edited by and
submission deadline 30 Sep 2025 | Viewed by 304 | Submission Open
Keywords: behavioral neuropharmacology; molecular neuropharmacology; neuropharmacology; neurological disorders; neurodegenerative diseases
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Selected Papers in the 3rd International Electronic Conference on Biomedicines (ECB 2025) submission deadline 30 Sep 2025 | Viewed by 302 | Submission Open
Keywords: insulin resistance or hyperinsulinemia; immunotherapy and adverse effects; tumor microenvironment; immune system; tumor immunology; autoimmune disease; cardiovascular diseases; diabetes; obesity; metabolic diseases; gene therapy; gene editing; cell therapy; rare diseases; neurodegeneration
(This special issue belongs to the Section Molecular and Translational Medicine)
Applications of Mass Spectrometry-Based Methods to Explore the Impact of Circadian Rhythms on Disease
edited by Robin Joshi
submission deadline 30 Sep 2025 | Viewed by 291 | Submission Open
Keywords: circadian biology; metabolomics; multiomics; method development; circadian biology; mass spectrometry; proteomics and post-translational modifications in disease; translational medicines; chronopharmacology
(This special issue belongs to the Section Biomedical Engineering and Materials)
DNA Methylation Profiling for the Classification and Diagnosis of Tumors
edited by
submission deadline 30 Sep 2025 | Viewed by 288 | Submission Open
Keywords: DNA methylation; tumors; central nervous system; soft tissues; haematolymphoid tumors; diagnostic tool
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
Advances in Drug Discovery and Development Using Mass Spectrometry
edited by Emily G. Werth, and Lin-Zhi Chen
submission deadline 30 Sep 2025 | Viewed by 284 | Submission Open
Keywords: LC/MS; proteomics; protein therapeutics; PTMs; immunocapture; CQAs
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Immunogenetic Regulations for Disease Prognosis
edited by Anshuman Mishra and
submission deadline 30 Sep 2025 | Viewed by 255 | Submission Open
Keywords: immunity; host susceptibility; gene expression; biotechnology; disease resistance; immunogenicity; drug monitoring; vaccines; adaptive immunity
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
Medicinal Cannabis: Advances in Therapeutics and Clinical Applications
edited by
submission deadline 30 Sep 2025 | Viewed by 215 | Submission Open
Keywords: medicinal cannabis; cannabidiol (CBD); cannabigerol (CBG); cannabinoid; cannabinol (CBN)
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Roles of Extracellular Vesicles in the Complex Interaction Between Metabolic Disorder and Cancer
edited by
submission deadline 30 Sep 2025 | Viewed by 215 | Submission Open
Keywords: extracellular vesicles; metabolic disorders; obesity; diabetes; cardiovascular diseases; cancer; mechanism; diagnosis; treatment
(This special issue belongs to the Section Molecular and Translational Medicine)
Skin Fibrosis and Cutaneous Wound Healing—2nd Edition submission deadline 30 Sep 2025 | Viewed by 207 | Submission Open
Keywords: fibroblasts; inflammation; fibrosis; cutaneous wound healing
(This special issue belongs to the Section Molecular and Translational Medicine)
Urticaria: New Insights into Pathogenesis, Diagnosis and Therapy
edited by
submission deadline 30 Sep 2025 | Viewed by 206 | Submission Open
Keywords: acute urticaria; chronic urticaria; pathogenesis; mast cells; biomarkers; diagnosis; biologicals
(This special issue belongs to the Section Molecular and Translational Medicine)
Prostate Cancer Pathology: Recent Advances and Future Perspectives
edited by
submission deadline 30 Sep 2025 | 1 articles | Viewed by 202 | Submission Open
Keywords: prostate cancer; pathology; digital pathology; Gleason grading; molecular biomarkers; precision medicine; molecular pathology; molecular profiling; therapy resistance
(This special issue belongs to the Section Cancer Biology and Oncology)
Neuroscience Through Electrophysiology: Current Trends and Future Directions
edited by
submission deadline 30 Sep 2025 | Viewed by 188 | Submission Open
Keywords: electrophysiology; neural circuit; synaptic plasticity; neuronal membrane; patch-clamp; action potential; ion channels; neurodevelopmental disorders; neurodegenerative disorders
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Mycobacterial Infections: Insights into Pathogenesis, Diagnosis, and Treatment
edited by
submission deadline 30 Sep 2025 | Viewed by 169 | Submission Open
Keywords: mycobacterium; pathogenesis; host– pathogen interactions; virulence factors; antimicrobial resistance; diagnosis; therapeutics; host-directed therapy; vaccine development; drug resistance
(This special issue belongs to the Section Microbiology in Human Health and Disease)
Advances in Oral Squamous Cell Carcinoma Research
edited by Sangang Wu
submission deadline 30 Sep 2025 | Viewed by 158 | Submission Open
Keywords: oral squamous cell carcinoma; diagnostic biomarkers; therapeutic strategies; tumor microenvironment; radiotherapy; single-cell sequencing; artificial intelligence in oncology; personalized medicine; molecular mechanism; recurrence and metastasis
(This special issue belongs to the Section Cancer Biology and Oncology)
Bone Diseases: Pathophysiology and Molecular Biology
edited by , and Nicola De Gasperis
submission deadline 30 Sep 2025 | Viewed by 151 | Submission Open
Keywords: bone diseases; osteoporosis; osteoarthritis; Paget’ s disease; bone tumors
(This special issue belongs to the Section Molecular and Translational Medicine)
Immune Checkpoint Molecules and Cancer Immunotherapy
edited by Zhiyuan Qin and Shujing Liu
submission deadline 30 Sep 2025 | Viewed by 149 | Submission Open
Keywords: immune checkpoint molecules; cancer immunity; tumor immune microenvironment; cancer immunotherapy; biomarkers
(This special issue belongs to the Section Immunology and Immunotherapy)
Advances in Immunotherapy and Radiation Therapy for Cancer (2nd Edition)
edited by and Benjamin Spieler
submission deadline 30 Sep 2025 | Viewed by 148 | Submission Open
Keywords: radiotherapy; immunotherapy; outcome; toxicity; normal tissue; abscopal; tumor; systemic; local; response
(This special issue belongs to the Section Cancer Biology and Oncology)
State-of-the-Art Dermatology in Spain submission deadline 30 Sep 2025 | Viewed by 147 | Submission Open
Keywords: dermatological research; dermatology; skin disease; psoriasis; atopic dermatitis; urticaria; alopecia areata
(This special issue belongs to the Section Molecular and Translational Medicine)
Emerging Trends in Cardioimmunology: Pathomechanisms and Therapeutic Strategies
edited by
submission deadline 30 Sep 2025 | Viewed by 146 | Submission Open
Keywords: cardiovascular diseases; inflammation; auto-immunity; pathological remodeling; immunomodulation; treatment strategies
(This special issue belongs to the Section Immunology and Immunotherapy)
Advanced Research in Metabolic Syndrome (2nd Edition)
edited by
submission deadline 30 Sep 2025 | Viewed by 145 | Submission Open
Keywords: obesity; diabetes; dyslipidemia; hypertension; microcirculatory damage; ischemia– reperfusion; necro-apopto-autophagy; laboratory animals; bioactive agents
(This special issue belongs to the Section Cell Biology and Pathology)
Lymphomas: From Mechanisms to Therapeutic Approaches
edited by Delfa Radić-Krišto and
submission deadline 30 Sep 2025 | Viewed by 141 | Submission Open
Keywords: aggressive lymphomas; cellular therapy; cellular immunotherapy; translational medicine; lymphomagenesis; indolent lymphomas; phase I/II clinical trials; targeted therapy; biomarkers; in vitro and in vivo models of lymphomas
(This special issue belongs to the Section Cancer Biology and Oncology)
New Advances in Gastroenterology and Hepatology: Special Focus on Microvesicles
edited by Fabrizio Pizzolante
submission deadline 30 Sep 2025 | Viewed by 141 | Submission Open
Keywords: cirrhosis; hepatocellular carcinoma; metabolic-associated fatty liver disease; inflammatory bowel disease; liquid biopsy; microvescicals
(This special issue belongs to the Section Cell Biology and Pathology)
Epilepsy: Pathomechanism, Diagnostics, and Novel Treatment Options submission deadline 30 Sep 2025 | Viewed by 138 | Submission Open
Keywords: epilepsy; pathophysiology; neurobiology; molecular pathways; experimental models of epilepsy; neuroinflammation; seizure prediction; biomarker discovery; electrophysiological studies; precision neurology
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Advances Research on Nanomedicine
edited by
submission deadline 30 Sep 2025 | Viewed by 136 | Submission Open
Keywords: multifunctional nanomaterials; nanomedicine; tumor; theranostics; artificial intelligence (AI); immunotherapy
(This special issue belongs to the Section Biomedical Engineering and Materials)
Advanced Cancer Diagnosis and Treatment: Third Edition
edited by and Hideshi Ishii
submission deadline 30 Sep 2025 | Viewed by 134 | Submission Open
Keywords: cancer biology; epigenetics; early detection; diagnosis; biodiagnosis; novel therapeutics; new paradigms
(This special issue belongs to the Section Cancer Biology and Oncology)
Immunotherapy and Targeted Treatment in Solid Tumors: Biomarkers and Novel Therapeutic Strategies submission deadline 30 Sep 2025 | Viewed by 131 | Submission Open
Keywords: immunotherapy; targeted therapy; biomarkers; tumor microenvironment; molecular profiling; precision oncology; treatment resistance; solid tumors; translational oncology
(This special issue belongs to the Section Cancer Biology and Oncology)
Unveiling the Genetic Architecture of Complex and Common Diseases submission deadline 30 Sep 2025 | Viewed by 120 | Submission Open
Keywords: polygenetic score; cardiovascular disorders; metabolic disorders; neurodegenerative disorders
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
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