Advances in Atherosclerosis and Associated Diseases: From Molecular Mechanisms to Personalized Therapeutic Approaches
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".
Deadline for manuscript submissions: 31 December 2026 | Viewed by 132
Special Issue Editors
Interests: platelets; pharmacology; microcirculation; glycocalyx; thrombosis and hemostasis
Special Issues, Collections and Topics in MDPI journals
Interests: psychotherapy; psychotic disorders; brain; neuropsychoanalysis; affective neurosciences
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Atherosclerosis is a chronic, progressive vascular disease characterized by lipid accumulation, endothelial dysfunction, and persistent inflammation within the arterial wall, and remains the leading underlying cause of major cardiovascular conditions, including coronary artery disease, stroke, and peripheral artery disease. In particular, insulin resistance and neuroinflammation have emerged as critical yet underexplored contributors to vascular pathology. Insulin resistance precedes the development of type 2 diabetes by many years, causing, in the meantime, significant damage to our organism, particularly at the cardiovascular level. Microglial activation, blood–brain barrier dysfunction, and systemic inflammatory signaling may all contribute to both atherosclerotic progression and its neurological complications.
This Special Issue aims to bring together cutting-edge research and reviews that explore the complex interplay between vascular biology, insulin resistance, inflammation, and systemic regulation in atherosclerosis and related disorders. Research areas may include, but are not limited to, the following topics:
- Molecular and cellular mechanisms of atherosclerosis development and progression;
- Neuroinflammation and the neurovascular interface in atherosclerosis;
- Crosstalk between the central nervous system and the cardiovascular system;
- Microglia, astrocytes, and blood–brain barrier dysfunction in vascular disease;
- Biomarkers for early detection and prognosis;
- Advanced imaging techniques for vascular and neurovascular inflammation;
- Multi-omics approaches (genomics, transcriptomics, proteomics, and metabolomics) in atherosclerosis research;
- Epigenetic and epitranscriptomic regulation of vascular inflammation;
- Novel therapeutic targets and drug development;
- Brain networks and biomarker research.
We look forward to receiving your contributions.
Dr. Patricia Pia Wadowski
Dr. Henriette Löffler-Stastka
Guest Editors
Manuscript Submission Information
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Keywords
- atherosclerosis
- coronary artery disease
- stroke
- neuroinflammation
- vascular inflammation
- cardiovascular disease
- cardiovascular biomarkers
- novel therapeutic strategies
- precision medicine
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