Extracellular Vesicles: A New Frontier in Liquid Biopsy

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cell Biology and Pathology".

Deadline for manuscript submissions: 30 April 2026 | Viewed by 52

Special Issue Editors


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Guest Editor
Department of Oncology, Renmin Hospital of Wuhan University, Wuhan, China
Interests: tumor biomarker; liquid biopsy; extracellular vesicle; cancer immunotherapy

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Guest Editor
Graduate Institute of Biomedical Optomechatronics, Taipei Medical University, Taipei, Taiwan
Interests: extracellular vesicles therapy; biomaterial; cancer diagnostics; neurodegeneration disease

Special Issue Information

Dear Colleagues,

Extracellular vesicles (EVs) have emerged as a transformative component of liquid biopsy, offering unprecedented opportunities for noninvasive cancer diagnosis, prognosis, and therapeutic monitoring, as well as the noncancerous disease like Alzheimer’s disease. EVs encapsulate a diverse array of biomolecules—including proteins, nucleic acids, and metabolites—that reflect the physiological and pathological state of their cell of origin. Recent advances in high-throughput profiling, nanotechnology, and bioinformatics have greatly enhanced our ability to characterize EVs with high sensitivity and specificity, establishing their value as dynamic biomarkers across a wide spectrum of cancers and other diseases. This Special Issue, “Extracellular Vesicles: A New Frontier in Liquid Biopsy”, aims to highlight cutting-edge research on the biology, methodology, and clinical applications of EVs. We welcome submissions that focus on novel EV detection platforms, multi-omics approaches, EV-based biomarkers for early detection and minimal residual disease monitoring, as well as their integration into precision oncology and therapeutic decision making. Both original research and comprehensive reviews are encouraged, with the goal of accelerating translational efforts and fostering collaboration between basic scientists, clinicians, and industry leaders to realize the full potential of EVs in clinical practice.

Dr. Chen Zhao
Dr. You-Ren Ji
Guest Editors

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Keywords

  • extracellular vesicles (EVs)
  • liquid biopsy
  • circulating biomarkers
  • exosome
  • nanomedicine
  • translational oncology
  • precision medicine

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Published Papers

This special issue is now open for submission.
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